2017 Cell Biology Therapies 
Drug Target Review
OCTOBER 2, 2024
Cell and gene therapies (CGTs) have made significant advancements in treating oncological diseases, with therapies like CAR-T cell treatments transforming cancer care. However, cell-based therapies are intended to leverage those healthy cells via transplant to regenerate damaged tissue.
Drug Target Review
AUGUST 24, 2023
Neutralising GDF-15 with CatalYm’s anti-GDF-15 antibody visugromab was shown to reverse its inhibitory effects and to re-sensitise tumours to anti-PD-1 treatment, achieving commensurate survival benefit of anti-GDF-15-anti-PD-1 combination therapy in vivo. in North America) in late 2017. Current Opinion in Cell Biology.
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The Pharma Data
MARCH 16, 2022
The research scientist at the Max Planck Institute for Medical Research received the award in recognition of his ground-breaking work in establishing various approaches to protein labeling in living cells that have enabled far-reaching advances in chemical and cell biology. Protein labeling (e.g.
Drug Target Review
NOVEMBER 17, 2023
They recognise ‘cell stress molecules’ on the surface of infected, old, injured and cancerous cells without the need for complex pre-stimulation signals of the adaptive immune system (eg, T cells). NK cells can be readily extracted from umbilical cord blood or peripheral blood of adult donors.
Broad Institute
OCTOBER 11, 2023
By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. The team found that deleting the gene Ptpn2 made tumors sensitive to PD-1 therapy, and they published their findings in Nature in 2017.
DrugBank
JUNE 27, 2023
Their use, as well as their integration into other types of data, has enabled the development of more precise therapies. 50 , 1700391 (2017). Genetics 205 , 1003–1035 (2017). 16 , 70–70 (2017). 44 , 195–211 (2017). References 1. König, König, I. Von Mutius, E. &
Codon
APRIL 9, 2024
With help from the Global Fund to Fight AIDS, Tuberculosis, and Malaria (GFATM), artemisinin-based combination therapy became much more economically accessible worldwide. When Louis Miller, now Chief of Malaria Cell Biology at the NIH, attended a malaria conference in Shanghai in 2008, he asked: Who discovered artemisinin?
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