SCIENMAG: Medicine & Health

AUGUST 2, 2023

Researchers have found that robots can have a ‘U-shaped’ effect on profits: causing profit margins to fall at first, before eventually rising again.

Research 88

Research 88

Broad Institute

OCTOBER 4, 2023

Researchers from the Tumor Immunotherapy Discovery Engine ( TIDE ) at the Broad Institute of MIT and Harvard, AbbVie, and Calico Life Sciences report that the molecule simultaneously makes tumors more sensitive to immune attack and boosts the activity of immune cells to fight tumors in mice.

Small Molecule 128

Small Molecule Clinical Trials Trials Engineering 128

keypoint

APRIL 16, 2024

These Next-Generation Grants aim to encourage and support early-career researchers who are applying disruptive concepts and inventive processes to advance human immunology, vaccine discovery, and immunotherapy research.

Vaccine 81

Vaccine International Research 81

PPD

JUNE 20, 2024

Acceleration in every step of clinical research is critical to pharmaceutical developers. Yet, today’s clinical research sponsors face significant challenges. Rather than accepting the persistent delays in clinical research as disruptive, yet unavoidable, we believe they underscore the need for greater efficiency.

Clinical Research 52

Clinical Research Research Clinical Trials Pharmaceuticals 52

Drug Target Review

NOVEMBER 25, 2024

As the CEO of iOnctura, an innovative oncology biopharmaceutical company she co-founded in 2017, Catherine has played a key role in advancing the development of highly targeted small molecules aimed at revolutionising cancer treatment. I went on to complete my MBA and PhD at The Institute of Cancer Research (ICR) in drug development.

Treatment 52

Treatment Small Molecule Clinical Trials Trials 52

Drug Target Review

JULY 10, 2023

Despite decades of research and development, there are currently no drugs that can prevent or cure these diseases and only limited options for symptomatic relief. In summary, CNS research is a rapidly evolving field with a multitude of exciting developments and breakthroughs. 2017 Dec 11;9(1). 2017 Sep 1;49(9):1373–84.

Research 52

Research Disease Treatment Drug Development 52

FDA Law Blog: Biosimilars

MARCH 29, 2024

According to GAO, FDA is facing challenges with clinical research inspections to ensure that the sites that oversee the research that lead to drug approvals meet the necessary standards. These are BIMO inspections of hospitals, clinical research organizations (CROs), and other similar facilities where clinical trial work is performed.

Clinical Research 59

Clinical Research FDA Research Clinical Trials 59

Advarra

JUNE 12, 2023

Gene therapy research is exciting and full of promise, but because of the risks involved, it’s also highly regulated, requiring an institutional biosafety committee (IBC) to provide additional oversight and risk assessment. IRBs are tasked with protecting research subject’s rights and welfare. How are IBCs Different from IRBs?

Engineering 98

Engineering Therapies Regulations Research 98

Conversations in Drug Development Trends

AUGUST 10, 2023

With so many exciting developments in the last few years, it’s critical for the psychedelic community to come together to reflect on our progress, share the latest discoveries, and discuss the future of psychedelic research. Reflecting back on my conference experience, there are three key takeaways that stand out: 1.

Science 98

Science Clinical Trials Trials Clinical Research 98

Drug Target Review

JANUARY 25, 2024

Researchers from the Cleveland Clinic, led by Dr Ofer Reizes and Dr Justin Lathia, have developed a therapeutic peptide that disrupts the molecular processes behind aggressive cancer cell growth. 3 Therefore, the researchers aimed to disrupt this complex to limit the cancerous properties of the cells. Journal of Biomedical Science.

Treatment 106

Treatment Clinical Trials Science Research 106

NIOSH Science Blog: Drugs

AUGUST 2, 2023

A recently published research article explored patterns and characteristics of workers’ compensation injury claims over a 17-year period among firefighters in Ohio. Based on data from the OHBWC claims database, the researchers analyzed a comprehensive set of injury claims filed by firefighters from 2001-2017.

Research 68

Research 68

Broad Institute

OCTOBER 15, 2024

After completing his PhD in 2017, Brown joined Xavier’s lab as a postdoctoral researcher and has been at the Broad ever since, now as a staff scientist. We spoke with Brown about his experience as both a researcher and a patient in this #WhyIScience Q&A. What keeps you motivated to keep doing research?

Disease 125

Disease Immune Response Research Science 125

Drug Target Review

APRIL 19, 2024

After ten years of exciting postdoctoral research around Europe in the astroparticle physics sector, hunting for dark matter at yet another offer from a foreign institution, I chose to create space for my life instead. Pure theoretical research is not in my chords, and I felt uncomfortable not being challenged by data. To participate.

Molecular Biology 111

Molecular Biology Research Pharmaceuticals Small Molecule 111

Drug Hunter

JUNE 5, 2023

Glecaprevir, or ABT-493, was approved in combination with pibrentasvir (Mavyret) for the treatment of Hepatitis C (HCV) in 2017. A Proprietary Catalyst in Roche’s Synthesis of Danoprevir Some pharmaceutical research teams have elected to develop and patent their own catalysts, with impressive results. Gonzalez-Bobes, F. Poongavanam, V.;

Process Chemistry 206

Process Chemistry Drugs Production Clinical Development 206

Broad Institute

APRIL 22, 2024

She is also a member of the steering committee for the Berkeley AI Research (BAIR) Lab. From 2007 to 2017 she was at Microsoft Research, through Cambridge, MA (2014-2017), Los Angeles (2008-2014), and Redmond, WA (2007-2008). She completed her Ph.D. Previous Jenn Nava Next Jesse Boehm

Molecular Biology 52

Molecular Biology Engineering Science Research 52

Alta Sciences

MARCH 4, 2025

Addressing New Challenges in Human Abuse Potential Research The CCALC has held face-to-face meetings in collaboration with industry, academia, and the FDA once every two to three years since inception, and has provided much of the industry perspective on the practical challenges and solutions to assessing abuse and dependence potential.

Clinical Trials 52

Clinical Trials FDA Drug Development Trials 52

SCIENMAG: Medicine & Health

JULY 5, 2023

In 2017, the Nobel Prize in Medicine was bestowed upon researchers who made significant breakthroughs in […] This internal clock regulates vital physiological processes including sleep, metabolism, hormonal fluctuations, body temperature, and blood pressure.

International 59

International Regulations Research 59

The Pharma Data

JANUARY 13, 2021

13, 2021 — From 2010 to 2017, there were significant increases in the estimated rates of neonatal abstinence syndrome (NAS) and maternal opioid-related diagnoses (MOD), according to a study published in the Jan. In the national sample, there were 751,037 birth hospitalizations and 748,239 delivery hospitalizations in 2017.

Hospitals 52

Hospitals Research 52

Drug Target Review

AUGUST 16, 2023

Utilising just 15ul of patient serum samples, the researchers tested it with silver nanowires for various cancer types, capturing molecular vibrational changes indicative of altered physiology and pathology in cancer samples. References 1. Jillian Phallen. Direct detection of early-stage cancers using circulating tumor DNA.

DNA 98

DNA Disease Therapies Treatment 98

Drug Target Review

NOVEMBER 17, 2023

CAR-NK cell trials only commenced in 2017 and most are still recruiting patients. She obtained her PhD from the University of Wollongong in 2015 and gained extensive research experience as a postdoctoral fellow at Swinburne University of Technology, CSIRO, and Monash University, in the fields of immunology and tissue engineering.

Therapies 118

Therapies Clinical Trials Cell Biology Trials 118

Drug Target Review

SEPTEMBER 26, 2023

Human derived induced pluripotent stem cells (hiPSCs) have revolutionised research and are increasingly used for toxicology screening and disease modelling. 27,28 Since the advent of hiPSC technology almost two decades ago enormous progress has been made in many areas of research. 2017 Jan;155(1):234–47. 2017 Jul 6;21(1):14–7.

Drugs 112

Drugs FDA Disease Animal Testing 112

KIF1A

JUNE 17, 2023

Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. The researchers assessed KIF1A’s speed, distribution, and ability to transport both small and large cargo across these 16 mutations. What’s a pre-print? .

Laboratories 98

Laboratories Therapies Disease Research 98

keypoint

JANUARY 23, 2023

On March 24, 2023, Keystone Symposia will hosted a live ePanel event featuring the recipients of the Michelson Prizes: Next Generation Grants , an international prize that supports early-career researchers who are applying disruptive concepts and inventive processes to advance human immunology, vaccine discovery, and immunotherapy research.

Vaccine 52

Vaccine International Research 52

Broad Institute

MARCH 8, 2024

On average, biomedical researchers do not receive their first major grant until the age of 43. Support The Next Generation Awards have strengthened Boston’s biomedical ecosystem by bolstering the careers of emerging scientists, helping them launch their own labs and develop as leaders in the research community.

Research 52

Research 52

Drug Target Review

DECEMBER 19, 2023

I don’t think it is a question of neuroscientists having to shoulder the responsibility of responding to and addressing questions of eco-anxiety, climate change, and environmental change, but rather a matter of upping the interest in this space and delivering more evidence through great research. I talked about methylmercury.

Science 116

Science Bioethics International Research 116

The Pharma Data

JANUARY 7, 2021

The pharmaceutical product landscape is rapidly and fundamentally changing with profound impact on research and development strategy and technology needs. The number of biopharmaceutical products show a considerable growth accounting for nearly a quarter of the new molecular entities approved in 2017.

Production 52

Production FDA Pharmaceuticals Marketing 52

New Drug Approvals

NOVEMBER 13, 2023

Vodobatinib can be used for chronic myeloid leukemia (CML) research. Vodobatinib can be used for chronic myeloid leukemia (CML) research [1] [2]. VODOBATINIB 1388803-90-4 Molecular Weight 453.92 Vodobatinib exhibits activity against most BCR-ABL1 point mutants, and has no activity against BCR-ABL1T315I.

Treatment 62

Treatment Disease Therapies Production 62

The Pharma Data

JANUARY 26, 2021

Department of Agriculture (USDA) recommendations for fruit and vegetable intake, respectively, in 2017, according to research published in the Jan. Data from the 2017 national and state Youth Risk Behavior Surveys were analyzed to calculate the percentage of students meeting intake recommendations. TUESDAY, Jan. Samantha J.

Disease 52

Disease Research 52

Drug Target Review

OCTOBER 17, 2023

This research was published in Cell. 2017 July [cited 2023 October 9]; 3(2):45-51. Metabolic changes such as increased arginine levels could serve as biomarkers for detecting cancer at an early stage, which is essential for successful cancer treatment and patient survival. References 1 Krafts K, Ray SD, Yang N. Cell Proliferation.

Regulations 98

Regulations Therapies Treatment Disease 98

Drug Target Review

JUNE 19, 2024

Because this programme is still in early research, we are not at a point we can say we definitely know what it is going to work best in setting X or setting Y. Prior to joining Lineage, Mr Culley served from August 2017 to September 2018 as interim Chief Executive Officer at Artemis Therapeutics, Inc. SVRA) in April 2017.

Therapies 84

Therapies Small Molecule Pharmaceutical Companies Molecular Biology 84

Drug Target Review

FEBRUARY 2, 2024

What specific limitations in mirroring diseases in humans are commonly observed when using animal models for preclinical research? We foresee that the use of animal models to assess efficacy and eventually toxicity will decrease, reducing the number of animals sacrificed for research. Prior to Organovo, Mr.

Drugs 116

Drugs Clinical Trials Disease Science 116

Broad Institute

JUNE 14, 2023

Glimcher is a distinguished immunologist, widely renowned for her work in one of the most promising areas of cancer research. Beering Award for outstanding research contributions to advancement of biomedical or clinical science; and the L'Oréal-UNESCO Award for Women in Science. She has also received the 2017 George M.

Medical Schools 52

Medical Schools Immune Response Science Hospitals 52

Broad Institute

MAY 23, 2024

We conclude with an outlook for the future with “AI scientists” as generative agents capable of skeptical learning and reasoning to empower biomedical research.

Medical Schools 45

Medical Schools Research Drugs 45

Broad Institute

SEPTEMBER 15, 2023

TBD By lcopelan@broadinstitute.org September 15, 2023 Alex Lu Microsoft Research New England MIA About Current Schedule Video Playlist Resources All talks Contact us MIA Talks Search - Any - Fall 2023 Spring 2023 Spring 2024 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring (..)

Research 40

Research 40

Broad Institute

AUGUST 8, 2024

Group Leader, Research Scientist Kan Xiong is a group leader in the Gerstner Center for Cancer Diagnostics at the Broad Institute of MIT and Harvard. Xiong joined the center at the end of 2017. Nucleic Acids Res. 2022;50(1):e1. doi:10.1093/nar/gkab855 Kan Xiong, Ph.D.

DNA 52

DNA Science Research 52

New Drug Approvals

SEPTEMBER 13, 2024

21] In August 2017, it was announced that Cerecor had sold its rights to aticaprant to Janssen Pharmaceuticals. [22] 22] [21] Janssen was also experimenting with esketamine for the treatment of depression as of 2017. [21] 21] In August 2017, it was announced that Cerecor had sold its rights to aticaprant to Janssen Pharmaceuticals. [22]

Treatment 62

Treatment Clinical Trials Pharmacokinetics Pharmaceuticals 62

The Pharma Data

DECEMBER 15, 2020

teens plateaued this year, but still they remain high, researchers report. Data from the most recent annual Monitoring the Future survey, conducted by the University of Michigan’s Institute for Social Research, show that from 2017 to 2019, the percentage of teens who said they vaped nicotine in the past 12 months doubled: 7.5%

Research 52

Research Drugs 52