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Lineage Cell Therapeutics Provides End of Year Shareholder Letter

The Pharma Data

NYSE American and TASE: LCTX), a clinical-stage biotechnology company developing allogeneic cell therapies for unmet medical needs, today provided a year-end review and an outline of its plans for 2021. CARLSBAD, Calif.–( –( BUSINESS WIRE )– Lineage Cell Therapeutics, Inc.

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Tezepelumab NAVIGATOR Phase 3 Trial Met Primary Endpoint Of A Statistically Significant And Clinically Meaningful Reduction In Exacerbations In A Broad Population Of Patients With Severe Asthma

The Pharma Data

Food and Drug Administration Breakthrough Therapy Designation granted to tezepelumab in Sept. 2018 for patients with severe asthma, without an eosinophilic phenotype. TSLP is released in response to multiple triggers associated with asthma exacerbations, including allergens, viruses and other airborne particles.

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Update On SOURCE Phase 3 Trial For Tezepelumab In Patients With Severe, Oral Corticosteroid-Dependent Asthma

The Pharma Data

In September 2018 , the US Food and Drug Administration granted Breakthrough Therapy Designation for tezepelumab in patients with severe asthma, without an eosinophilic phenotype. TSLP is released in response to multiple triggers associated with asthma exacerbations, including allergens, viruses and other airborne particles.

Trials 40
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Sanofi delivered close to double-digit Q4 2020

The Pharma Data

At the end of 2020, Dupixent ® was launched in 47 countries with approximately 230 000 patients on therapy. The ISTH guidelines suggest treatment with Cablivi ® in combination with plasma exchange and immunosuppressive therapy for first episode or relapse in all adult aTTP patients. Net sales (€ million). Libtayo ® sales in the U.S.

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Sanofi delivered close to double-digit Q4 2020 business EPS(1) growth at CER

The Pharma Data

At the end of 2020, Dupixent ® was launched in 47 countries with approximately 230 000 patients on therapy. The ISTH guidelines suggest treatment with Cablivi ® in combination with plasma exchange and immunosuppressive therapy for first episode or relapse in all adult aTTP patients. Net sales (€ million). Libtayo ® sales in the U.S.

Vaccine 52
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Sanofi continued its growth trajectory. Strong increase in Q1 2021 business EPS(1) at CER

The Pharma Data

At the end of the first quarter, Dupixent ® was launched in 49 countries with approximately 260 000 patients on therapy. . to €24 million, primarily due to the COVID-19 pandemic, which has led to a decrease in infused immune reconstitution therapies such as Lemtrada ®. Neurology and Immunology. Net sales (€ million). Lemtrada ®.

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