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In recent years, a novel approach known as condensate biology has emerged, revolutionising the way researchers think about drug discovery and development. Dewpoint Therapeutics, a platform drug discovery company founded in 2018, has been at the forefront of this exciting field.
2018 Jun 13;5. Role of autotaxin in cancer stem cells. 2018 Sep;37(2–3):509–18. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. The Journal of CellBiology. References: Ninou I, Magkrioti C, Aidinis V. Frontiers in Medicine.
Turning this tide, Professor Jens Christian Schwamborn, a cellbiology expert at the University of Luxembourg and co-founder of OrganoTherapeutics , is leading a groundbreaking effort to transform our understanding and treatment of these debilitating diseases.
When I was studying cellbiology, looking at how cells divide, I couldn’t fathom how math could possibly fit into that. My undergraduate studies focused on biochemistry and cellbiology, so very much STEM-based, but my professors and mentors noticed my penchant for critical thinking which led me to consider law.
She joined the company in November 2018 with more than 10 years of experience in drug discovery and non-clinical development of immunomodulatory drugs in the immuno-oncology space. Shear forces induce ICAM-1 nanoclustering on endothelial cells that impact on T-cell migration. Current Opinion in CellBiology.
Innate Pharma’s commercial-stage product, Lumoxiti, in-licensed from AstraZeneca in the US, EU and Switzerland, was approved by the FDA in September 2018. Lumoxiti is a first-in class specialty oncology product for hairy cell leukemia.
2018 Jun;558(7711):553-558. [2] 2018 Apr;93(4):251-258. [3] Kang Y, Kuybeda O, de Waal PW, Mukherjee S, Van Eps N, Dutka P, Zhou XE, Bartesaghi A, Erramilli S, Morizumi T, Gu X, Yin Y, Liu P, Jiang Y, Meng X, Zhao G, Melcher K, Ernst OP, Kossiakoff AA, Subramaniam S, Xu HE. Many Targe Sriram K, Insel PA. Mol Pharmacol.
Monalizumab may re-establish a broad anti-tumor response mediated by NK and T cells, and may enhance the cytotoxic potential of other therapeutic antibodies (André et al, Cell2018). Lumoxiti is a first-in class specialty oncology product for hairy cell leukemia.
Public Health 39 , 153–168 (2018). 33 , 11–12 (2018). Network expansion of genetic associations defines a pleiotropy map of human cellbiology. Obama White House Archive. Remarks by the President on Precision Medicine. whitehouse.gov [link] (2015). Jaccard, E., Waeber, G. &
This paves the way for exploring ways to stimulate this machinery in aging cells, potentially offering new avenues for therapeutics. An ambitious research journey The interdisciplinary nature of this research, combining computational biology, immunology, cellbiology, and biophysics, was instrumental in its success.
Activated follicles will mature into antral follicles, consisting of a fully grown oocyte surrounded by several layers of different types of ovarian somatic cells. In 2018, Saitou’s team reported the first method to coax human PGC-like cells into the oogonia stage.
Protein nitration assays are widely used in many research areas including but not limited to biochemistry , biotechnology , cellbiology , microbiology , and molecular biology. 2018 Aug 29;9(1):3505. Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer. Nat Commun.
Nature Reviews Molecular CellBiology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular CellBiology (2014). Artificial Life (2018).
Nature Reviews Molecular CellBiology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular CellBiology (2014). Artificial Life (2018).
She has a background in cellbiology, biophysics and pharmacology and was a professor and Chair at the University of Kansas for over 20 years. She has numerous awards including Ingram Magazines 50 Kansans You Should Know, the 2018 Kansas Entrepreneur of the Year Award and the Marjorie S.
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