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Condensate biology: advancing drug discovery for complex diseases

Drug Target Review

In recent years, a novel approach known as condensate biology has emerged, revolutionising the way researchers think about drug discovery and development. Dewpoint Therapeutics, a platform drug discovery company founded in 2018, has been at the forefront of this exciting field.

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Innate Pharma 2021 Financial Calendar

The Pharma Data

Innate Pharma’s commercial-stage product, Lumoxiti, in-licensed from AstraZeneca in the US, EU and Switzerland, was approved by the FDA in September 2018. Lumoxiti is a first-in class specialty oncology product for hairy cell leukemia.

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First Patient Dosed in Monalizumab Phase 3 Clinical Trial Triggers $50M Payment From AstraZeneca

The Pharma Data

Monalizumab may re-establish a broad anti-tumor response mediated by NK and T cells, and may enhance the cytotoxic potential of other therapeutic antibodies (André et al, Cell 2018). Lumoxiti is a first-in class specialty oncology product for hairy cell leukemia.

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Making Eggs Without Ovaries

Codon

Activated follicles will mature into antral follicles, consisting of a fully grown oocyte surrounded by several layers of different types of ovarian somatic cells. In 2018, Saitou’s team reported the first method to coax human PGC-like cells into the oogonia stage. Then, I induce the signaling pathways involved in meiosis.

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The Codon Guide to Synthetic Biology

Codon

Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Progress in biology is arguably moving faster today than at any point in the course of human history. Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. Nature Reviews Molecular Cell Biology (2009).

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The Codon Guide to Synthetic Biology

Codon

Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Last edit: 13 September 2023 Progress in biology is arguably moving faster today than at any point in the course of human history. Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. Artificial Life (2018).

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New advances in hormone replacement therapy set to transform care

Drug Target Review

Lisa is a fellow in the American Institute of Medical and Biological Engineering. She has a background in cell biology, biophysics and pharmacology and was a professor and Chair at the University of Kansas for over 20 years.