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Who are the AACR Scientific Achievement Award winners?

Drug Discovery World

He is being recognised for his revolutionary contributions to developing the first gene-edited cell-based therapy for cancer that involves the genetic re-engineering of a patient’s own T cells to combat their disease, and for demonstrating that adoptive T-cell therapy can induce remission and in some cases cure patients with advanced cancer.

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Women in Stem with Ashley Hall

Drug Target Review

When I was studying cell biology, looking at how cells divide, I couldn’t fathom how math could possibly fit into that. My undergraduate studies focused on biochemistry and cell biology, so very much STEM-based, but my professors and mentors noticed my penchant for critical thinking which led me to consider law.

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Cancer immunotherapy: GDF-15’s role in Anti-PD-1 resistance

Drug Target Review

Neutralising GDF-15 with CatalYm’s anti-GDF-15 antibody visugromab was shown to reverse its inhibitory effects and to re-sensitise tumours to anti-PD-1 treatment, achieving commensurate survival benefit of anti-GDF-15-anti-PD-1 combination therapy in vivo. Current Opinion in Cell Biology. Biophysical Journal.

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Precision Medicine in the Genomic Era

DrugBank

Their use, as well as their integration into other types of data, has enabled the development of more precise therapies. 14 As an unbiased method for genetic variant detection, GWAS holds the promise of identifying new genes and gene regulation mechanisms underlying a variety of conditions, including complex diseases. Waeber, G. &

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Making Eggs Without Ovaries

Codon

Activated follicles will mature into antral follicles, consisting of a fully grown oocyte surrounded by several layers of different types of ovarian somatic cells. In 2018, Saitou’s team reported the first method to coax human PGC-like cells into the oogonia stage.

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The Codon Guide to Synthetic Biology

Codon

Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). Artificial Life (2018).

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The Codon Guide to Synthetic Biology

Codon

Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). Artificial Life (2018).

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