2018 FDA Approval Metabolic Stability Treatment 
Metabolite Tales Blog
MAY 12, 2023
In 2021, almost one third of FDA approved drugs contained at least one fluorine. This was surprising given that replacement of a phenyl with a pyrimidine and fluorination of aryl or heteroaryl rings are techniques often used to increase metabolic stability. Bourgeois, James A. Perkins, Arsany A. Abouda, Kahari J.
Metabolite Tales Blog
APRIL 4, 2023
Metabolism of 2022 FDA approved small molecule drugs part 2 Mixing it Up By Julia Shanu-Wilson In Part 1 of this topic we looked at metabolism of the small molecule drugs approved by the FDA in 2022 that were mediated by CYP3A4. Dermavant’s tapinarof is one such friend. We hope it was a useful two-parter!
Expert insights. Personalized for you.
52 
Let's personalize your content