Breaking C-F bonds in drugs
Metabolite Tales Blog
MAY 12, 2023
In 2022, fewer of the 19 newly FDA approved small molecule drugs contained F atoms (adagrasib, lenacapavir, oteseconazole, vonoprazan), but this was followed by 3 more approvals of F-containing drugs in the first quarter of 2023 alone (pirtobrutinib, omaveloxolone, leniolisib). Bourgeois, James A. Perkins, Arsany A. Abouda, Kahari J.
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