Broad Institute

JANUARY 14, 2025

In 2018, Liu, who works on the same floor as Minikel and Vallabh at Broad, approached them and proposed a collaboration. His lab had just developed base editing, a gene-editing approach that makes single-letter changes in DNA and can shut down protein production using strategies including installing a stop signal in the genetic code.

Disease 144

Disease DNA Protein Production Treatment 144

The Pharma Data

JANUARY 16, 2021

Etta Biotech”), to set up a high titer transient protein expression platform for high quality protein production using JS Bio’s transient transfection media. JS Bio becomes the exclusive cell culture supplier for Etta Biotech’s transient transfection high titer protein expression platform.

Protein Expression 52

Protein Expression Protein Production Production Drug Development 52

Drug Target Review

JULY 5, 2023

5 And for the latter, the development of a technique to temporally track gene expression in CHO cells, which therefore has the potential to lead to the identification of targets to improve recombinant protein production. 2018) 34(6): 1460-1471. PDA J Pharm Sci Technol (2018), 72(4): 438-450. Wang B, Albanetti T, et al.

Engineering 105

Engineering DNA Laboratories Production 105

Broad Institute

MAY 14, 2024

When proteins are the desired end result, the E. coli molecular machinery for translating mRNA into proteins is used after the T7 system makes the RNA. Studier continued studying the T7 polymerase and promoter, fine-tuning the system for years, and publishing new improved versions as recently as 2018.

RNA 84

RNA Production Molecular Biology Laboratories 84

The Pharma Data

MARCH 23, 2022

Back in 2018, researchers tested a broad-spectrum antiviral candidate called remdesivir/VEKLURY, which acts as a nucleotide decoy to get incorporated into the viral RNA genome and stop viral polymerase. . “The virus hijacks this protein and makes it do something different than its normal job in cells.

Virus 52

Virus Small Molecule Protein Production Research 52

Drug Target Review

DECEMBER 10, 2024

Alex earned her MS in Technology Management from Wentworth Institute of Technology in 2018. Prior to Sunflower Therapeutics, Alex was a Laboratory Technical Assistant at the Massachusetts Institute of Technology.

Protein Production 98

Protein Production Production Engineering Vaccine 98

BMG Labtech

FEBRUARY 24, 2025

8 A second sandwich ELISA with absorbance detection allowed measurement of the concentrations of the S100 calcium-binding protein (S100B). Advanced oxidation protein products were also determined (Fig. 2018 Aug 29;9(1):3505. Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer.

Small Molecule 52

Small Molecule Disease Licensing Licensing 52