Drug Discovery World

APRIL 30, 2024

Reece Armstrong explores the potential and future opportunities for mRNA-based therapies. Messenger RNA (mRNA) has come into focus within the drug discovery and development as an exciting tool to deliver genetic information. For instance, consider how at the end of 2018, the mRNA therapies market was valued at $3.43

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Therapies RNA Vaccine Small Molecule 130

Drug Discovery World

AUGUST 1, 2023

1 August was first chosen as World RNA Day in 2018 as a play on AUG (adenine, uracil and guanine), a triple sequence of RNA (called a codon) that initiates protein synthesis by the cell. Since then, it has been observed to publicise the importance of this molecule in the generation of proteins in the body.

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RNA Vaccine Drugs Disease 130

The Pharma Data

MARCH 23, 2022

In fact, antiviral therapies designed to treat viruses such as hepatitis C (Sofosbuvir/SOVALDI) work by blocking viral polymerase. Back in 2018, researchers tested a broad-spectrum antiviral candidate called remdesivir/VEKLURY, which acts as a nucleotide decoy to get incorporated into the viral RNA genome and stop viral polymerase. .

Virus 52

Virus Small Molecule Protein Production Research 52

Codon

AUGUST 10, 2023

Artificial Life (2018). Nature Biotechnology (2018). Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Science (2018). Link An integrated cell-free metabolic platform for protein production and synthetic biology , by Jewett M.C. eLife (2018).

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DNA Cell Biology Molecular Biology Engineering 91

Codon

AUGUST 10, 2023

Artificial Life (2018). Nature Biotechnology (2018). Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Science (2018). Link The PURE system for the cell-free synthesis of membrane proteins , by Kuruma Y. & & Shamir R. Nucleic Acids Research (2010).

DNA 52

DNA Cell Biology Engineering Molecular Biology 52