BioPharma Drive: Drug Pricing

OCTOBER 22, 2024

A medicine the pharma acquired in a $430 million buyout of Visterra in 2018 succeeded in a Phase 3 trial in IgA nephropathy, a crowded corner of drug research.

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Science Daily: Pharmacology News

OCTOBER 23, 2024

A recovery program increased their population by 2010, but from 2014 to 2018, it fell to 30% of its peak due to a new acanthocephalan parasite, exacerbated by a prolonged drought. A research effort employed morphological and molecular methods, alongside necropsy records, to identify the parasite and assess its health impacts on the foxes.

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Drugs.com

JUNE 9, 2023

Researchers found that between 2018 and 2021, U.S. FRIDAY, June 9, 2023 -- Young American adults have doubled their use of non-LSD hallucinogens in just a few years, a new report warns. adults aged 19 to 30 increased their use of mescaline, peyote,

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Drug Target Review

NOVEMBER 3, 2023

Organoid group (Hubrecht Institute) researchers, collaborating with researchers at the Princess Máxima Center and Maastricht University, used gut organoids to perform a systematic CRISPR screening of 1800 human transcription factors. 2018 February 8 [2023 November 1];172(4):650-65. The study was published in Science.

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Covalent Modifiers

FEBRUARY 6, 2024

3c04710 Covalent drug discovery has been a challenging research area given the struggle of finding a sweet balance between selectivity and reactivity for these drugs, the lack of which often leads to off-target activities and hence undesirable side effects.

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The Pharma Data

NOVEMBER 30, 2020

TDR, in partnership with the WHO Global Tuberculosis Programme, has developed an interactive web-based toolkit that supports national TB programmes and other partners to conduct implementation research designed to evaluate digital technologies for TB care. Research methods. Developing IR objectives and questions. Knowledge translation.

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Crown Bioscience

JUNE 6, 2024

In a significant development, the US Food and Drug Administration’s (FDA) Center for Drug Evaluation and Research (CDER) approved 55 new drugs in 2023. This marks the second-highest count in the past 30 years, with the highest being 59 new drug approvals in 2018 and represents an impressive 50% increase in drugs approved in 2022.

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Codon

NOVEMBER 3, 2024

Even after microbiologists discovered the bacterium that causes the illness in 1882, it wasn’t until the 1920s that researchers were able to develop a vaccine for TB. Chilean research participants aged 15 to 35 who received the vaccine during a case-control study , for example, only showed a 10 percent reduced risk of pulmonary TB.

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Broad Institute

NOVEMBER 4, 2024

Related news Novo Nordisk Foundation and Broad Institute of MIT and Harvard launch new research center for genomic mechanisms of disease Like many research endeavors, the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease at the Broad Institute of MIT and Harvard (NNFC) grew out of a conversation between scientists.

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Antidote

JULY 29, 2022

Between 2009 and 2018, U.S. In 2019 alone, research and development spending totaled $186 billion for the global pharmaceutical industry. The process of getting a new drug to market is an expensive one. billion to bring a new therapy to market.

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Drug Target Review

SEPTEMBER 4, 2023

Infectious agents’ resistance was described at the European Union Research Parliament “as a widespread, multifaceted phenomenon that affects both living things and the environment, as well as their capacity to survive in the presence of drugs intended to either kill or inactivate them.” References: Antunes Luisa (2023). Suruchi, A.,

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SCIENMAG: Medicine & Health

JUNE 13, 2023

People who adhere to global Cancer Prevention Recommendations are putting themselves at lower risk of developing the disease, new research confirms. Experts at Newcastle University have reviewed evidence of following the 2018 World Cancer Research Fund (WCRF) and American Institute for Cancer Research (AICR) lifestyle-based recommendations.

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Drug Target Review

NOVEMBER 1, 2023

2 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. 1-5 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. He is a researcher at University of Oldenburg, Germany. 2018 Jun 13;5.

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Conversations in Drug Development Trends

FEBRUARY 28, 2023

Rob found out that in 1980, a researcher in Birmingham, England first synthesized a very niche cancer drug in a small lab. This treatment only exists because a small charity in the ’70s donated the funds needed for the researcher to discover it. But what was truly remarkable? It really has to start from square one,” says Rob.

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On Medicine

MAY 11, 2023

I undertook a service evaluation exploring this in 2018 ( Poster 134 ), which showed potential for reduced length of stay and hypoglycemia rates, however, the cost was a 30% increase in workload. Integrating research into clinical care is increasing, especially among specialist services.

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KIF1A

MAY 4, 2024

Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. In this week’s article, researchers in Brazil identified a KIF1A mutation in a cohort of patients with congenital ataxia.

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Drug Target Review

JULY 9, 2024

The researchers hypothesised that these mutations in DNA repair genes might control cancer mutation rates, which was validated in organoids grown from patient tumour samples. She continued: “The really interesting finding from our research is what happens afterwards. Cancer Research UK. Cancer Research UK. Open Biology.

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The Pharma Data

MARCH 21, 2022

For research and development, an extra US$ 1.1 Building on lessons learnt from COVID-19 research, there is a need to catalyse investment and action to accelerate the development of new tools, especially new TB vaccines. Between 2018–2020, 20 million people were reached with TB treatment. billion per year is needed.

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National Drug & Alcohol Research Centre Blog

JULY 13, 2021

NCCRED was funded through the Strategy, and commenced in 2018, to build clinical research capacity and work towards establishing evidence-based treatment approaches for both methamphetamines and other emerging drugs of concern. Why do a clinical research priority setting study?

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FDA Law Blog: Drug Discovery

JULY 17, 2024

An Opportunity to Leverage the Newly Created Rare Disease Advisory Committee across CDER and CBER In Frank and James’ 2018 proposal there was also a recommendation for the formation of a Rare Disease Advisory Committee, which would allow FDA access to experts in the science of small trials and other aspects of rare disease research.

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Drug Target Review

JANUARY 25, 2024

Researchers from the Cleveland Clinic, led by Dr Ofer Reizes and Dr Justin Lathia, have developed a therapeutic peptide that disrupts the molecular processes behind aggressive cancer cell growth. 3 Therefore, the researchers aimed to disrupt this complex to limit the cancerous properties of the cells. Available from: [link]

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Drug Target Review

MARCH 3, 2025

His research focuses on creating advanced cell culture models, such as brain organoids and assembloids, derived from patient-specific stem cells. In this interview, Professor Schwamborn discusses his research, the promise of brain organoids, and his vision for the future of stem cell-based therapies.

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SCIENMAG: Medicine & Health

JULY 19, 2023

Using an innovative method for measuring doctor turnover, Weill Cornell Medicine researchers determined that between 2010 and 2018, the annual rate at which physicians left their practices increased by 43 percent, from 5.3 percent to 7.6 percent a year.

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The Pharma Data

JUNE 29, 2021

AstraZeneca today appointed Dr. Susan Galbraith to lead Oncology Research & Development from initial discovery through late-stage development. In 2017, she was awarded an honorary Doctorate of Medical Science from the Institute of Cancer Research (ICR), and in 2018 was admitted to the Fellowship of the Academy of Medical Sciences.

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Molecule Blog

AUGUST 19, 2021

TL;DR: This week, the first university biomedical intellectual property (IP) and research project was funded as an NFT (non-fungible token), enabled by a pioneering innovation at Molecule. The IP-NFT enables new fundraising and collaboration strategies for researchers by combining legal and technical frameworks with NFT technology.

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Broad Institute

JULY 10, 2023

Thanks in part to her research, more geneticists are now studying a wider diversity of people and accounting for genetic ancestry in their analyses. Through this work, Martin is showing how a methodical, data-driven kind of social justice can help improve equity in scientific research and lead to better science.

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Drug Target Review

FEBRUARY 28, 2024

Preclinical research on γδ T cells has made great strides since the cells were first identified in the 1980s, with γδ T-cell therapies from several companies, including IN8bio, now in or nearing clinical trials for various cancers. from 2003 to 2006, covering the biotechnology and life-science tools sectors.

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Drug Hunter

JUNE 5, 2023

A Proprietary Catalyst in Roche’s Synthesis of Danoprevir Some pharmaceutical research teams have elected to develop and patent their own catalysts, with impressive results. Organic Process Research & Development 2018 , 22 (8), 918–946. Gonzalez-Bobes, F. Poongavanam, V.; Kihlberg, J.

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Broad Institute

JULY 6, 2023

A new approach from a team led by researchers in the Cardiovascular Disease Initiative at the Broad Institute of MIT and Harvard and at Massachusetts General Hospital (MGH) significantly improves the accuracy of genetic risk prediction of heart disease across all ancestries.

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SCIENMAG: Medicine & Health

JULY 25, 2023

Researchers from Mathematica studied high-performing Comprehensive Primary Care Plus (CPC+) sites to identify key strategies that contributed to significant reductions in acute hospitalization rates.

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Hospitals Research 59

SCIENMAG: Medicine & Health

AUGUST 4, 2023

The research, which included all women in Wales who gave birth between 2018 and 2021, found that breastfeeding rates at six months were higher during Covid compared to the pre-pandemic period – with rates increasing from 16.6 A Swansea University-led study revealed breastfeeding rates in Wales increased during the pandemic.

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The Pharma Data

MARCH 22, 2022

Boehringer Ingelheim supports young scientists and veterinarians dedicated to ruminant health research Submissions for Ruminant Well-Being Awards and Gustav Rosenberger Memorial Fund grant open now. That is why we foster research and support young scientists and veterinarians dedicated to ruminant health research.

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Broad Institute

JANUARY 22, 2024

Since 2018, the Cancer Dependency Map (DepMap) Consortium , an academic-industrial partnership launched by the Broad, has uncovered several potential drug targets by systematically screening cancer models in search of genetic dependencies. How have researchers looked for cancer dependencies in the past?

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Drug Target Review

SEPTEMBER 26, 2023

Human derived induced pluripotent stem cells (hiPSCs) have revolutionised research and are increasingly used for toxicology screening and disease modelling. 27,28 Since the advent of hiPSC technology almost two decades ago enormous progress has been made in many areas of research. 2018 Mar;17(3):167–81. Cell Stem Cell.

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SCIENMAG: Medicine & Health

SEPTEMBER 12, 2023

In the summer of 2018, graduate student Hunter Dean from the Medical Scientist Training Program came to Yuhua Song, Ph.D., with a research idea. He wanted to pursue his doctoral research at the University of Alabama at Birmingham in Alzheimer’s disease — under the joint mentorship of Song, who had never worked […]

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Drug Target Review

NOVEMBER 6, 2023

Advances in research and development and the utilisation of combination treatment strategies are revolutionising the haematology care landscape, but more must be done to address patients’ individual needs. Published 2018 Nov 13. Available at: [link] Accessed October 2023. Falzone L, Salomone S, Libra M. Front Pharmacol.

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Drug Target Review

MARCH 26, 2024

In my role as Chief Business Development Officer at Osivax, my main challenge is taking the deep scientific work of our research & development team and simplifying it for various audiences Could you share an example of a specific project or research that you have worked on and the impact it has had in your field?

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