The Pharma Data

JANUARY 12, 2021

Overall Cancer Death Rates Decreased From 1991 to 2018. 12, 2021 — Overall cancer death rates have decreased continuously from 1991 to 2018, according to a study published online Jan. percent from 2014 to 2018 for men, from 1.8 percent from 2014 to 2018 for men, from 1.8 Professional. TUESDAY, Jan. Siegel, M.P.H.,

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Drug Target Review

OCTOBER 11, 2023

Most of these conditions are genetic in origin and the majority have no effective treatment. That includes countless rare peripheral diseases, including many for which there are currently no treatments. Boosting autophagy won’t be the only road to new treatments for rare genetic diseases but it is a vital one to take.

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The Pharma Data

NOVEMBER 19, 2020

2010 to 2018 Saw Decrease in Rate of Death for People With HIV. 19, 2020 — From 2010 to 2018, there was a 36.6 from the CDC in Atlanta, and colleagues examined age-adjusted death rates per 1,000 PWDH during 2010 to 2018 using data from the National HIV Surveillance System for persons aged 13 years and older. Professional.

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Common Sense for Drug Policy Blog

NOVEMBER 29, 2023

Receipt of Opioid Use Disorder Treatments Prior to Fatal Overdoses and Comparison to No Treatment "The findings revealed that exposures to MOUD, even if not continued throughout the six-month exposure period was associated with reduced risk of a fatal poisoning compared to non-MOUD forms of treatment and no treatment exposure.

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Drug Discovery World

APRIL 22, 2024

The treatment becomes only the second CAR-T cell therapy to secure routine funding for use in the NHS, and the only one for treating ALL in children and young adults under 26 years old. It is approved in cancers that are refractory, in relapse post-transplant or in second or later relapse.

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Drugs.com

FEBRUARY 15, 2024

He didn’t think much of it until 2018, when he began to feel ill and dropped more than 40 pounds. THURSDAY, Feb. 15, 2024 -- Mick worked in a factory boiler room in the 1970s, where he was exposed to asbestos. The diagnosis: malignant.

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Common Sense for Drug Policy Blog

JUNE 4, 2023

Opioid Substitution Treatment in the UK "Opioid substitution therapy (OST) is an evidence-based treatment for opioid dependency, with treatment engagement shown to be protective against drug related deaths ( Santo et al., 2019 ; Public Health England, 2018 ). dwf_admin Sun, 06/04/2023 - 20:03 Source Poulter, H.

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Drug Discovery World

MARCH 12, 2024

Three of these are key to the advancement of gene therapies, cancer research and Parkinson’s treatments.

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Drug Discovery World

DECEMBER 18, 2023

Casgevy The committee recommended granting a conditional marketing authorisation for Casgevy (exagamglogene autotemcel), an advanced therapy medicinal product (ATMP) for the treatment of transfusion dependent beta-thalassemia and severe sickle cell disease.

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The Pharma Data

DECEMBER 17, 2020

18, 2020 /PRNewswire/ — Camurus AB (NASDAQ STO: CAMX) announced today that the Swiss agency for therapeutic products, Swissmedic, has approved weekly and monthly Buvidal ® prolonged release buprenorphine for the treatment of opioid dependence in adults and adolescents from 16 years of age. LUND, Sweden , Dec. About Buvidal.

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Drug Discovery World

JANUARY 31, 2023

Hundreds of people with an aggressive form of lymphoma are set to benefit from the first personalised immunotherapy treatment to be recommended for routine use in the NHS. Best supportive care usually includes salvage chemotherapy, which is given after the cancer has not responded to other treatments.

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Drug Discovery World

JUNE 14, 2023

The recent clinical trial for metastatic breast cancer patients (DESTINY-Breast04) found that a treatment traditionally used for HER2 positive patients was also effective in patients considered HER2 negative. It used the current CAP/ASCO testing algorithm for HER2 protein expression levels.

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Drug Discovery World

DECEMBER 5, 2022

A recent study revealed that traditional research sources are missing evidence for up to 70% of clinically encountered variants, information that is essential to developing treatments for genetic disorders. Mike Graglia founded the SynGAP Research Fund when his son was diagnosed with SYNGAP1 in 2018.

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Drug Discovery World

MARCH 17, 2023

Since 2018, GARDP and the University of Liverpool have been working together to advance new treatment options for new-borns with sepsis. New treatment options are needed to respond to growing drug resistance to the current WHO-recommended regimen, especially in many low- and middle-income countries.

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Drug Discovery World

JULY 25, 2023

Complex lung diseases, such as idiopathic pulmonary fibrosis (IPF) and pulmonary hypertension, currently have limited treatment options and poor survival rates. To address this, and to improve outcomes for patients, Qureight was founded by clinicians and researchers in Cambridge in 2018.

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The Pharma Data

NOVEMBER 26, 2020

26, 2020 — In isolated areas of the United States, nurse practitioners are filling an important role in helping people access treatment for opioid addiction, according to a Washington State University (WSU) study. By late 2018, nurse practitioners were writing nearly 20% of buprenorphine prescriptions in rural Oregon, the study found.

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Drug Discovery World

JANUARY 17, 2024

With oncology accounting for a third of pharma’s product pipeline, significant challenges include fierce competition, high research and development costs over, 10-15 years for clinical development, and pressures to rapidly meet the demand for new treatments 2-4.

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Drug Discovery World

SEPTEMBER 1, 2023

The new therapeutics companies BII has accepted into the Venture Lab acceleration programme are: Loma Therapeutics, which is developing targeted immunotherapy for efficient and safe treatment of patients with HPV infection, dysplasia, and cancer. Since its inception in 2018, BII has supported 87 start-ups and projects.

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The Pharma Data

NOVEMBER 2, 2020

The World Health Organization’s (WHO) Global TB Programme welcomes the results from an important study on shortened treatment for drug-susceptible tuberculosis (TB) in children, presented at the 51 st virtual Union World Conference on Lung Health. Side-effects related to treatment were few, and similar across both groups.

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The Pharma Data

FEBRUARY 8, 2021

Janssen Announces Treatment with ERLEADA ® (apalutamide) Significantly Improved Overall Survival in Patients with Metastatic Castration-Sensitive Prostate Cancer. ERLEADA ® is an androgen receptor (AR) inhibitor indicated for the treatment of patients with nmCRPC and for the treatment of patients with mCSPC. 10 months. [5]

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Drug Target Review

JANUARY 25, 2024

These findings offer a novel strategy for developing targeted treatments for triple-negative breast cancer, which currently has no approved options. The peptide in development is based on a 2018 Cleveland Clinic discovery and serves as a proof-of-concept for this type of drug for triple-negative breast cancer. Available from: [link]

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The Pharma Data

JANUARY 11, 2021

-based subsidiary of Terumo and a global neurovascular company, announced today the FDA Approval of the PMA Supplement for the WEB 17 System, a new addition to the WEB Aneurysm Embolization System for the treatment of intracranial wide neck bifurcation aneurysms. The WEB System received its first PMA approval in late 2018.

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The Pharma Data

OCTOBER 26, 2020

Food and Drug Administration (FDA) has approved EYSUVIS for the short-term treatment of dry eye disease. . EYSUVIS is the first FDA-approved corticosteroid specifically for dry eye disease treatment. Over-the-counter treatments fail due to the body’s natural protective system. 25% for dry eye disease treatment.

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The Pharma Data

JANUARY 25, 2021

26, 2021 /PRNewswire/ — Dynacure , a clinical-stage company focused on developing and commercializing novel therapies to transform the lives of patients with rare diseases who have limited or no treatment options, announced today that the U.S. STRASBOURG, France and PHILADELPHIA , Jan. ” The U.S.

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The Pharma Data

APRIL 17, 2021

Biogen’s expansion in China now includes treatment options approved for relapsing MS and spinal muscular atrophy. today announced that China’s National Medical Products Administration (NMPA) has approved TECFIDERA ® (dimethyl fumarate) for the treatment of relapsing multiple sclerosis (MS). About TECFIDERA ® (dimethyl fumarate) .

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Drug Discovery World

JANUARY 23, 2023

Following the release of Clarivate’s report ‘RNA Technology Companies to Watch’, DDW’s Diana Spencer speaks to Strand Therapeutics’ Jacob Becraft and HAYA Therapeutics’ Samir Ounzain to find out how this technology could revolutionise disease treatment. DS: How will your work ultimately impact disease treatment?

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The Pharma Data

OCTOBER 14, 2020

This is the first time the FDA has approved a treatment specifically for Ebola, which has caused a number of deadly outbreaks. Since 2015, BARDA has partnered with Regeneron to develop a life-saving treatment for Ebola Zaire,” said Gary Disbrow, acting director of BARDA. Yancopoulos, president and chief scientific officer of Regeneron.

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Drug Discovery World

OCTOBER 9, 2023

Despite the size of the market and the global impact, there are currently no effective treatments. DS: As new variants begin circulating, what impact could this finding have on our understanding and the potential treatment of long Covid? DS: Why do you think we are no closer to treatments for long Covid?

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The Pharma Data

DECEMBER 7, 2020

based clinical trials investigating interventions for high blood pressure between 2009-2018, just 52 were exclusively in Black people. While the numbers grew over that decade – from 3.9% (3 of 77 trials) in 2009 to 6.2% (9 of 146) in 2018 – the increase was not enough to be statistically significant.

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The Pharma Data

MARCH 3, 2021

s (NYSE: PFE) supplemental New Drug Application (sNDA) for LORBRENA ® (lorlatinib), expanding the indication to include first-line treatment of people with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC). The FDA action also converts the 2018 accelerated approval to full approval. PRESCRIBING INFORMATION.

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Common Sense for Drug Policy Blog

JANUARY 5, 2024

of the US adult population, injected drugs in 2018. Much of this increase is likely attributable to increases in IDU, but it is important to consider methodological differences in the creation of this 2018 estimate vs the 2011 estimate. million PWID in 2011, which suggest the 2018 estimate is closer to 3 times higher than in 2011.

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Agency IQ

OCTOBER 6, 2023

In a first, FDA tackles treatments for stimulant use disorder A new draft guidance from the FDA gives developers a roadmap to advance the development of novel therapies to address stimulant use disorders. SAMSHA published an “ evidence-based resource guide ” on substance use disorder treatment in June 2020.

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Drug Discovery World

OCTOBER 2, 2023

Independent central reads: AI-assisted image assessment Image assessment is critically important as it provides data for evaluating the safety and efficacy of new treatments. This can lead to generation of more objective endpoints that might lead to a better assessment of treatment efficacy. Br J Radiol. Frontiers in Oncology.

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The Pharma Data

JULY 8, 2021

AstraZeneca’s Biologics License Application (BLA) for tezepelumab has been accepted and granted Priority Review for the treatment of asthma from the US Food and Drug Administration (FDA). Tezepelumab received Breakthrough Therapy Designation for patients with severe asthma, without an eosinophilic phenotype in September 2018.

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The Pharma Data

NOVEMBER 18, 2021

Eli Lilly and Company blazoned that registration is now open for the CHALLENGE-MIG clinical trial, the first and only head-to- head trial comparing twoanti-calcitonin gene- related peptide (CGRP) drugs for the preventative treatment of episodic migraine in grown-ups.1 gepants) may help people achieve the pretensions that count most to them.

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Drug Target Review

JANUARY 17, 2024

This insight could lead to potential therapies to prevent treatment resistance. Furthermore, the stem cell-like characteristics promote resistance to treatment through upregulation of efflux transporters, promotion of glioblastoma stem cell proliferation in neurogenic zones, and immune suppression.

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Drug Discovery World

OCTOBER 4, 2022

Oligomerix’s portfolio of compounds is expected to provide a potentially lower-cost treatment alternative and/or complement to the newly emerging high-cost therapeutic options such as the monoclonal antibody products. Global dementia prevalence is expected to increase to 152 million in 2050, a 204% increase compared to 2018.

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