2019 Clinical Development Process Chemistry 
Metabolite Tales Blog
JULY 5, 2023
With metabolic stability in mind, we take a look at the metabolism of some FDA approved synthetic macrocyclic drugs, and a few of those that were/are in clinical development where metabolism data was available. Journal of Medicinal Chemistry 62 (21), 9418-9437. Balazs et al., Drug Hunter article, June 2023. 20 (March 20, 2014).
Metabolite Tales Blog
JULY 5, 2023
With metabolic stability in mind, we take a look at the metabolism of some FDA approved synthetic macrocyclic drugs, and a few of those that were/are in clinical development where metabolism data was available. Journal of Medicinal Chemistry 62 (21), 9418-9437. Balazs et al., Drug Hunter article, June 2023. 20 (March 20, 2014).
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