The Pharma Data

DECEMBER 11, 2020

11, 2020 — From 1990 to 2019, there was an increase in the burden of cardiovascular disease (CVD) globally, according to a study published online Dec. The researchers found that prevalent cases of total CVD increased from 271 million in 1990 to 523 million in 2019, and the number of CVD deaths increased from 12.1

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The Pharma Data

DECEMBER 22, 2020

population increased in 2019, while the rate of drug overdose deaths increased from 2018 to 2019, according to two December data briefs published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics. population in 2019, an increase of 0.1 TUESDAY, Dec. years for the U.S.

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The Pharma Data

NOVEMBER 25, 2020

2016 to 2019 Saw Increase in Prepregnancy Obesity in U.S. 25, 2020 — From 2016 to 2019, there was an increase in prepregnancy obesity in the United States, according to a November data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics. percent in 2019).

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Elrig

APRIL 11, 2024

One of the great highlights of a:head’s work has been the ability to observe disease-specific phenotypes and profile clinically used therapeutics for their ability to alter neuronal network activity. The post How to develop drugs for neurological diseases | Insights from Josh Bagley first appeared on ELRIG.

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The Pharma Data

MAY 27, 2022

billion in Medicare funds in 2019 on drugs whose clinical benefits have yet to be confirmed by the Food and Drug Administration, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health suggests. billion on 36 of these drugs across 55 indications in 2019. federal government spent an estimated $1.8

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The Pharma Data

DECEMBER 22, 2020

22, 2020 — Before the COVID-19 pandemic hit, life expectancy in the United States rose in 2019 for the second year in a row, according to two new federal government reports. That would be a new record and represent 400,000 more deaths than were recorded for 2019. Centers for Disease Control and Prevention. TUESDAY, Dec.

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The Pharma Data

JANUARY 21, 2021

Percent of Kindergarteners Not Up to Date With MMR in 2019-2020. percent of kindergarteners were not up to date with measles, mumps, and rubella (MMR) vaccination and did not have an exemption in the 2019 to 2020 school year, according to research published in the Jan. Professional. THURSDAY, Jan. 21, 2021 — Overall, 2.3

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Drug Discovery World

JULY 2, 2024

The National Institutes of Health (NIH) is sponsoring a clinical trial to evaluate the safety of an investigational monoclonal antibody to treat enterovirus D68 (EV-D68), which can cause severe respiratory and neurological diseases such as acute flaccid myelitis (AFM).

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The Pharma Data

NOVEMBER 4, 2020

Adults Had Chronic Pain in 2019. 4, 2020 — In 2019, more than 20 percent of U.S. Centers for Disease Control and Prevention National Center for Health Statistics. percent of adults had chronic pain in 2019, and 7.4 Professional. Percent of U.S. WEDNESDAY, Nov. Zelaya, Ph.D., Zelaya, Ph.D.,

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SCIENMAG: Medicine & Health

AUGUST 15, 2023

. — Exposure to environmental chemicals, including those in common plastic products, has been linked with an increased risk of cardiovascular disease, or CVD, the leading cause of death worldwide. million people died from CVDs in 2019. According to the World Health Organization, 17.9

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Creative Biolabs

JANUARY 15, 2020

By understanding the mechanism of new product development, product screening and production processes, as well as the diseases and symptoms that drugs need to treat, CDER provides scientific and regulatory advices for products that are about to be brought to market.

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SCIENMAG: Medicine & Health

JUNE 8, 2023

Statement Highlights: A new American Heart Association scientific statement focuses on treatment strategies for pediatric cardiomyopathy (diseases of the heart muscle’s structure and function that may lead to heart failure and death) and is a companion to a 2019 scientific statement focused on diagnosis of the condition.

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Drug Discovery World

MAY 20, 2024

BenevolentAI’s strategic collaboration with AstraZeneca began in 2019, and originally focused on discovering potential new treatments for idiopathic pulmonary fibrosis (IPF) and chronic kidney disease (CKD). The collaboration was expanded in January 2022 to two new disease areas, heart failure and systemic lupus erythematosus (SLE).

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Drug Discovery World

JULY 19, 2024

She then moved into rare diseases and has been working on rare hepatic diseases for the last two decades, with a focus on the development of advanced therapies. Since 2014, Dr Gonzalez-Aseguinolaza has been head of the Gene Therapy Program at the Centro Investigación Médica Aplicada (CIMA), Universidad de Navarra, in Spain.

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Drug Discovery Today

MARCH 18, 2020

Drug Discovery Today has today published a pre print of an editorial by Yongtao Duan, Hai-Liang Zhu and Chongchen Zhou of Henan Provincial Key Laboratory of Children’s Genetics and Metabolic Diseases, Children’s Hospital Affiliated to Zhengzhou University, Zhengzhou, 450018, China

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The Pharma Data

DECEMBER 9, 2020

10, 2020 — Heart disease is the leading cause of death worldwide — accounting for one-third of deaths in 2019 — and the death toll continues to rise, a new paper says. China had the highest number of heart disease deaths last year, followed by India, Russia, the United States and Indonesia. WEDNESDAY, Dec.

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Drug Discovery World

FEBRUARY 8, 2023

A diversity study has shown that clinical trials should use real world diseases epidemiology data, rather than US Census Bureau race and ethnicity data, to ensure enrolment reflects the populations affected by different diseases. For example, US Census Bureau data indicates 13.4%

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Drug Discovery World

FEBRUARY 20, 2024

With capacity for up to 60 research scientists and employees, the company says the site will play a role in helping to drive innovation in the UK life sciences sector, with the ambition of bringing forward new medicines for patients living with inflammatory diseases. Gilead acquired MiroBio, an Oxford-backed research company, in 2022.

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The Pharma Data

JANUARY 27, 2021

27, 2021 — Heart disease remains the leading cause of death worldwide, with 18.6 million deaths attributed to cardiovascular disease (CVD) globally in 2019, according to a report from the American Heart Association published online Jan. According to the report, in 2019, about 18.6 WEDNESDAY, Jan. 27 in Circulation.

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Drug Discovery World

OCTOBER 16, 2023

University College London (UCL) spinout AstronauTx has closed a £48m ($61m) Series A financing to develop novel treatments for Alzheimer’s disease and other neurodegenerative disorders. The company was launched in 2019, initially to build on research from the Alzheimer’s Research UK UCL Drug Discovery Institute (UCL DDI).

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Broad Institute

JULY 10, 2024

A three-drug cocktail known as Trikafta has greatly improved patient quality of life since its development in 2019, but can cause cataracts and liver damage and must be taken daily at a cost of about $300,000 per year. There are more than 2,000 known variants of the CFTR gene, 700 of which cause disease.

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Advarra

AUGUST 16, 2022

A rare, or orphan, disease by definition affects a small percentage of the population — fewer than 200,000 people in the U.S. But the numbers add up, and taken together, rare diseases impact an estimated 30 million Americans. Since then, the FDA has significantly changed its approach to rare and orphan diseases.

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Drug Discovery World

NOVEMBER 13, 2023

Genome sequencing has been used to study typhoid fever in a study in Zimbabwe and understand how the disease has evolved to be resistant to treatment. In response, an emergency reactive vaccination campaign using Typhoid Conjugate Vaccine (TCV) was initiated in suburbs of Harare in 2019, providing moderate protection. Typhi strains.

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BioPharma Drive: Drug Pricing

AUGUST 28, 2023

The treatment, developed by a biotech Bayer acquired in 2019, appeared safe in a small trial and showed signs of an effect on disease progression.

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Drug Discovery World

JANUARY 2, 2024

A promising treatment option, JAK inhibitors act by blocking the JAK family kinases and inhibiting the inflammatory pathways involved in AD and other inflammatory diseases. They reviewed the available safety data and analysed the risk of 11 adverse events from 14 RCTs published between 2019 and 2022.

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Drug Discovery World

JULY 15, 2022

Pharmaceutical company Transpire Bio will work alongside drug delivery provider Recipharm to develop two inhaled medicines for the treatment of asthma and Chronic Obstructive Pulmonary Disease (COPD).? . Asthma is thought to affect over 300 million people and in 2019 caused 455,000 deaths 1. million people dying from the condition.

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Drug Discovery World

JULY 8, 2022

Immutep is looking to use IMP761 to address the root cause of autoimmune disease through its function to silence autoimmune memory T cells that accumulate at the disease site and which express LAG-3 as an “exhaustion marker. . 1 More so, follow up studies in 2021 show that IMP761 decreased effector T cell cytokine secretion.

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Drug Discovery World

SEPTEMBER 22, 2022

Pfizer will make a $20 million equity investment, have options to license CytoReason’s platform and disease models, and fund supplementary project support. CytoReason’s platform has reportedly provided Pfizer with insights in research and development programs across over 20 diseases. .

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Drug Discovery World

NOVEMBER 1, 2022

Its snapshot report aimed to provide both an overview of the sector in Australia to determine how the sector has changed since this data was collected in 2017 and 2019 2. . The number of employees behind our biotech companies has also expanded, increasing 21% compared with 2019 from approximately 87,397 people in 2019 to 105,569 in 2022.

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Drug Discovery World

FEBRUARY 12, 2024

Set against the backdrop of the awe-inspiring technological advances that we hear about on an almost daily basis, I can’t help feeling shocked that we have so little to offer people with strokes, dementia, most cancers, brain injuries, multiple sclerosis, motor neurone disease, osteoarthritis, Crohn’s disease, Parkinson’s disease … the list goes on.

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Drug Discovery World

SEPTEMBER 14, 2023

N Engl J Med 2019; 381(4):338-348. Europe has one of the highest rates of bladder cancer in the world 1 , with more than 203,000 patients diagnosed in 2020 alone 2. Patients with mUC, including FGFR-driven tumours, face a particularly poor prognosis and the need for innovative therapies remains high. Fernandez E, et al. J Clin Med.

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Conversations in Drug Development Trends

FEBRUARY 22, 2023

Rare Disease Day on February 28th is a chance for rare disease communities to come together as one and join in conversation with stakeholders searching for treatments, raising money to support research, and changing the way healthcare and governments interact with patients. In my case, my daughter Iris has GM1 gangliosidosis.

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The Pharma Data

OCTOBER 26, 2020

Food and Drug Administration (FDA) has approved EYSUVIS for the short-term treatment of dry eye disease. . adults have been diagnosed with dry eye disease, a chronic, episodic, multifactorial disease. It also increases your risk for inflamed cornea, cornea eye disease, corneal ulcers and injuries, and eye infections. .

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The Pharma Data

MAY 31, 2022

the completion of enrollment of its Phase 1 (Ph1), open-label trial of pluripotent stem cell-derived dopaminergic neurons in patients with Parkinson’s disease (PD). of BRT-DA01 in patients with Parkinson’s disease.?. The company was fully acquired by Bayer in 2019. The purpose of the?Ph1 preliminary?efficacy?of

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The Pharma Data

NOVEMBER 12, 2020

Committee A, which focuses on programme and budget matters, decided to recommend the adoption of the first-ever resolution on meningitis, which would approve a global roadmap to defeat meningitis by 2030 – a disease that kills 300,000 people annually and leaves one in five of those affected with devastating long-term consequences.

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Chemical Biology and Drug Design

NOVEMBER 13, 2023

SARS-CoV-2 is responsible for the coronavirus disease of 2019 (COVID-19) which is one of the most widespread and powerful infections affecting human lungs. WHO proclaimed the outbreak of the Ebola virus disease (EVD), in 2014 that killed hundreds of people in West Africa.

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Drug Discovery World

NOVEMBER 9, 2022

SZC is already used within NHS Scotland for hyperkalaemia as outpatient care for adults with chronic kidney disease (CKD) stage 3b to 5 and/or heart failure. . Patients can now access SZC in the emergency care setting for the treatment of acute, life-threatening hyperkalaemia alongside standard care. .

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