article thumbnail

Drug Discovery Today publishes editorial on new approaches to the discovery of novel agents against 2019-nCoV (COVID - 19)

Drug Discovery Today

Drug Discovery Today has today published a pre print of an editorial by Yongtao Duan, Hai-Liang Zhu and Chongchen Zhou of Henan Provincial Key Laboratory of Children’s Genetics and Metabolic Diseases, Children’s Hospital Affiliated to Zhengzhou University, Zhengzhou, 450018, China

article thumbnail

Changes to CDSCO’s Rules for Clinical Trials in India: New Drugs & Clinical Trial Rules 2019

ProRelix Research

Being the second most populous country in the world with skilled labor and good infrastructure, India is a favorable destination for clinical trials for a wide variety of diseases.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

U.S. Heart Disease Death Rates Have Fallen Sharply in Past 30 Years

Drugs.com

8, 2023 -- Fatal heart disease in the United States dropped about 4% a year between 1990 and 2019, but Americans need to quit smoking, drinking and overeating or those gains could be wiped out, according to new research. TUESDAY, Aug. The declining.

Disease 96
article thumbnail

RNA: The most attractive target in recent viral diseases

Chemical Biology and Drug Design

These strategies act by taking advantage of the weakness points of this attractive bioweapon to disable or attack it (itself), accordingly stop the entire viral reproduction, and effectively end the severe microbial infections such as the coronavirus disease 2019 (COVID-19).

RNA 100
article thumbnail

The genetic modifier approach: identifying the right target for rare diseases

Drug Target Review

Most rare diseases are caused by a single gene defect, but severity can vary considerably among patients. Modifier genes can help explain that variability and can alter or even prevent disease onset and progression, making them appealing therapeutic targets. However, the identification of these genes is challenging.

Disease 111
article thumbnail

Genetic tracing at the Huanan Seafood market further supports COVID animal origins

Science Daily: Pharmacology News

A new study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC).

Marketing 135
article thumbnail

Prime editing efficiently corrects cystic fibrosis mutation in human lung cells

Broad Institute

A three-drug cocktail known as Trikafta has greatly improved patient quality of life since its development in 2019, but can cause cataracts and liver damage and must be taken daily at a cost of about $300,000 per year. There are more than 2,000 known variants of the CFTR gene, 700 of which cause disease.