Drug Target Review

SEPTEMBER 4, 2023

There have been several studies that have reported the ability of infectious disease agents to be drug resistant. Infectious agent includes bacteria, virus, fungi, and parasites, and they are capable of causing disease in a living organism. 7,13 The use of Plants extract is important in drug discovery.

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Codon

AUGUST 26, 2024

When COVID-19 emerged in 2019, by contrast, mRNA vaccines developed by Pfizer and Moderna took just 326 days from the initial sequencing of the virus to gaining approval for emergency use. These drugs would be ideal tools to bridge the wait for a vaccine against a quickly-spreading virus.

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Chemical Biology and Drug Design

NOVEMBER 13, 2023

SARS-CoV-2 is responsible for the coronavirus disease of 2019 (COVID-19) which is one of the most widespread and powerful infections affecting human lungs. WHO proclaimed the outbreak of the Ebola virus disease (EVD), in 2014 that killed hundreds of people in West Africa.

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Broad Institute

AUGUST 31, 2023

Related News Next generation prime editing systems move closer to possible therapeutic applications New CRISPR genome editing system offers a wide range of versatility in human cells Prime editing technologies allow scientists to precisely edit the genome in a variety of ways and could one day be used to treat genetic diseases.

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The Pharma Data

APRIL 25, 2021

Nirsevimab demonstrate d protect ion against respiratory syncytial virus disease in healthy infants in Phase 3 trial. Respiratory Syncytial Virus (RSV) is the leading cause of hospitalization in all infants. 1 – 5. RSV is the most common cause of LRTI and the leading cause of hospitalizations in all infants.

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Broad Institute

JANUARY 30, 2024

Bhattacharyya wears many coats today, splitting his time between the Broad and the infectious disease ward at MGH, where a diagnostic method he developed at Broad is now being tested to see if it helps patients quickly receive the best antibiotics for their infections. million deaths attributed directly to resistant infections.

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Drug Target Review

OCTOBER 26, 2023

1 Adeno-associated virus (AAV) vectors are the leading platform for in vivo gene delivery for the treatment of various human diseases. It has been well established that exposure to wild-type AAV results in priming of the immune system against the virus. Adeno-associated virus vector as a platform for gene therapy delivery.

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The Pharma Data

SEPTEMBER 3, 2020

Johnson & Johnson Announces that Janssen’s COVID-19 Investigational Vaccine Candidate Prevents Severe Clinical Disease in Pre-clinical Studies. Johnson & Johnson Announces that Janssen’s COVID-19 Investigational Vaccine Candidate Prevents Severe Clinical Disease in Pre-clinical Studies.

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Drug Target Review

JANUARY 3, 2024

Most healthy people recover completely from the infection, but norovirus can be life-threatening in infants, the elderly and in those with underlying diseases. This is because this blocks the transmission chain, preventing the virus from spreading from cell to cell. 2019 November 4 [2023 December 18]; 34:11-26.

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The Pharma Data

NOVEMBER 20, 2020

Centers for Disease Control and Prevention shows. It found that about 14% (34 million) of adults smoked cigarettes in 2019, the same rate as in 2017 and 2018. About 4.5% (11 million) of adults were current e-cigarette users in 2019, compared with 3.2% The rate was 16% in 2016, the Associated Press reported. in 2018 and 2.8%

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Codon

JANUARY 21, 2024

Today, refined versions of these human challenge studies have become standard practice in testing vaccines for vector-borne diseases (e.g., yellow fever, malaria, and dengue), evaluating new drugs or treatments, and studying pathogenesis, the process by which a disease develops. How are disease targets selected for challenge trials?

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The Pharma Data

NOVEMBER 13, 2020

Centers for Disease Control and Prevention analysis finds. The death toll of 207,500 in 2019 was 50% higher than just three years earlier, The New York Times reported. No measles deaths were reported in the United States in 2019, but the country had the highest number of cases since 1992. © 2020 HealthDay.

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The Pharma Data

NOVEMBER 13, 2020

13, 2020 — Measles cases reached their highest number in 23 years in 2019, according to research from the World Health Organization and U.S. Centers for Disease Control and Prevention published in the Nov. Increases were reported in all WHO regions during 2017 to 2019. FRIDAY, Nov. ” More Information.

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Quanticate

JUNE 16, 2020

The leading cause of death in patients with coronavirus disease 2019 (COVID-19), caused by the virus ‘severe acute respiratory syndrome coronavirus 2’ (SARS‑CoV‑2), is respiratory failure from acute respiratory distress syndrome. [1]

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The Pharma Data

OCTOBER 19, 2020

New Guidance: The FDA issued and implemented new guidance, Enforcement Policy for Modifications to FDA-Cleared Molecular Influenza and RSV Tests During the Coronavirus Disease 2019 (COVID-19) Public Health Emergency. The assay targets on coronavirus-specific nanobodies and tests affinity and efficacy to prevent the virus infection. .

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The Pharma Data

MARCH 24, 2021

Strong R&D commitment to developing therapeutics against SARS-CoV-2 virus. Boehringer Ingelheim stepped up its investments in R&D significantly in 2020 in pursuit of innovative medicines and therapies for diseases for which no satisfactory treatments are available. billion EUR (2019: 3.78 billion EUR (2019: 2.72

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Codon

OCTOBER 13, 2024

Through genetic engineering, researchers have developed Golden Rice which can help address the problem of vitamin A deficiency , cotton that produces its own insecticide , virus-resistant papayas , and more. One of these is “citrus canker,” a bacterial disease that causes the fruits to develop necrotic lesions.

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PLOS: DNA Science

JUNE 13, 2024

The virus SARS-CoV-2 emerged in Wuhan, home of a premiere research institute that focuses on viruses. An altered virus could have escaped. Evidence that the virus emerged, or escaped, from the wildlife trade is lacking. Her points: 1. Coincidence? I’ve never thought so.

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The Pharma Data

FEBRUARY 24, 2022

Medicago, a biopharmaceutical company headquartered in Quebec City, and GlaxoSmithKline (GSK) today announced that Health Canada has granted approval for COVIFENZ®, COVID-19 vaccine, (plant-based virus-like particles [VLP], recombinant, adjuvanted). This vaccine is indicated for active immunization to prevent coronavirus disease 2019 (COVID?19)

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The Pharma Data

JANUARY 11, 2021

Pfizer and BioNTech reported that their COVID-19 vaccine appears to be effective against a key mutation in new variants of the SARS-CoV-2 virus that causes COVID-19. Centers for Disease Control and Prevention (CDC) to provide genomic sequencing of SARS-CoV-2 samples. A study published by the U.S. Other Industry News. and now 501.V2,

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Codon

FEBRUARY 27, 2024

Patient YY’s neighbors quickly started to become infected, passing on the virus in turn. While the consensus that emerged among experts was that the virus spread primarily via airborne transmission , it also made use of another route: fomite transmission. million people in 2019. 1 Subscribe to receive Asimov Press essays.

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The Pharma Data

FEBRUARY 1, 2021

They spent about an hour at the Huanan Seafood Market, which was the site of an outbreak of the virus in December 2019, the Associated Press reported. Initially, experts suspected the new coronavirus came from wild animals sold at the market, but the site has been largely ruled out as a source of the virus.

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The Pharma Data

SEPTEMBER 30, 2021

We anticipate to sharing developments from our leading vaccines pipeline which underscore our ongoing commitment to uncovering insights which will help prevent severe infectious diseases at every stage of life, especially in diseases with an unmet need like respiratory syncytial virus.”. Poster presentation number 1137.

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DrugBank

NOVEMBER 4, 2024

A study from Oxford University demonstrated that in 2019, 1.27 This decline in R&D is attributed to scientific challenges associated with identifying new antibiotic targets and the relatively low return on investment compared to other therapeutic areas like oncology or rare diseases.  million deaths associated with it.

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The Pharma Data

AUGUST 16, 2021

Vaccination is our most effective means of preventing COVID-19 infection – especially severe disease and hospitalization – and its profound impact on protecting lives is indisputable. We continuously strive to stay at least one step ahead of the virus. today announced that they have submitted Phase 1 data to the U.S.

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The Pharma Data

DECEMBER 2, 2020

Centers for Disease Control and Prevention. 13, 2019, which is more than a month earlier than previously thought. Centers for Disease Control and Prevention. Below are newsworthy items compiled by the Healthday staff: CDC To Shorten Recommended Quarantine Period.

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The Pharma Data

AUGUST 31, 2020

Detects, confirms and differentiates HIV-1 and HIV-2 infections providing clinicians with critical diagnostic data for personalised management of patients with HIV – from appropriate counseling on disease differences to targeted therapy. Centers for Disease Control and Prevention (CDC) estimated in 2018 that 1.2

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NIH Director's Blog: Drug Development

JUNE 30, 2020

It’s now clear that nearly everyone who recovers from coronavirus disease 2019 (COVID-19) produces antibodies that specifically target SARS-CoV-2, the novel coronavirus that causes the infection. Not surprisingly, all volunteers had produced antibodies in response to the virus. Yet many critical questions remain.

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The Pharma Data

OCTOBER 28, 2020

In the overall patient group with detectable virus at baseline, the average daily reduction in viral load through day 7 was a 0.36 About REGN-COV2 REGN-COV2 is a combination of two monoclonal antibodies (REGN10933 and REGN10987) and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19.

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The Pharma Data

MARCH 25, 2021

TAK-003 is Being Studied for the Prevention of Dengue Due to any Dengue Virus Serotype in Individuals Ages Four to 60. With limited options to prevent the disease, there is a pressing need for widely available dengue vaccines. About TAK-003. 4,5 Efficacy varied by serotype.

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The Pharma Data

DECEMBER 10, 2020

The FDA said Thursday that it has developed a test for COVID-19 in fecal matter, in an attempt to prevent the disease from being inadvertently transmitted during fecal transplantation. 1, 2019, until effective screening methods are implemented.”. We know now that the viral RNA is found in stool and infectious virus as well.

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PLOS: DNA Science

OCTOBER 12, 2023

In the final chapter of my 2012 book The Forever Fix: Gene Therapy and the Boy Who Saved It , I predicted that the technology would soon expand well beyond the rare disease world. Gene therapy clearly hasn’t had a major impact on health care, offering extremely expensive treatments for a few individuals with rare diseases.

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The Pharma Data

JANUARY 4, 2021

King has battled a series of health problems in life, including a near-fatal stroke in May 2019 and a heart procedure. Centers for Disease Control and Prevention has said that Covid-19 vaccines “are not interchangeable,” and that “the safety and efficacy of a mixed-product series have not been evaluated. .

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The Pharma Data

SEPTEMBER 17, 2020

The new Elecsys Anti-SARS-CoV-2 S test can quantitatively measure the level of antibodies against SARS-CoV-2 in patients who have been exposed to the virus. 3 Knowing a given population’s seroprevalence is important in understanding how to contain the spread of the virus, as well as how to safely ease lockdown restrictions.

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PerkinElmer

FEBRUARY 28, 2022

In early 2019, no one could have predicted that a novel coronavirus would sweep around the globe and cause one of the most significant health crises of recent times. Fast-forward to today, and thousands of scientists have turned their attention to studying SARS-CoV-2, the virus responsible for the current COVID-19 pandemic.

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The Pharma Data

JANUARY 3, 2021

InspirMed is a newly established subsidiary of TLC specializing in the development of inhalable liposome formulation programs, such as TLC19 for the treatment of Coronavirus disease 2019 (COVID-19) as well as other programs for severe acute and chronic pulmonary diseases. Cautionary Note on Forward-Looking Statements.

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The Pharma Data

AUGUST 27, 2020

The study found that obese people with the virus were twice as likely to end up in hospital and 74% more likely to be transferred to an intensive care unit. The research was conducted by the University of North Carolina (UNC), the Saudi Health Council and the World Bank. They were also 48% more at risk of dying than non-obese people. .

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