Drug Target Review

APRIL 26, 2023

Scientists from the Massachusetts Institute of Technology (MIT) and the University of Massachusetts Medical School (UMass), US, have collaborated to create a novel type of nanoparticle that can deliver messenger RNA that encodes for beneficial proteins to the lungs.

RNA 98

RNA Medical Schools Engineering DNA 98

PLOS: DNA Science

MAY 16, 2024

Many of the links below are to some of the 100+ DNA Science posts that I wrote during the pandemic. ” I’ve long thought that SARS-CoV-2, or an immediate viral predecessor, emerged years before 2019 – at least as far back as 2013. But I think about that time often, and the warning that it sounded.

Virus 98

Virus DNA RNA Vaccine 98

Codon

JULY 27, 2023

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. billion units of DNA code are transcribed into more than a hundred volumes, each a thousand pages long, in type so small as to be barely legible.” LEGO robot to make sucrose gradients.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JULY 27, 2023

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. billion units of DNA code are transcribed into more than a hundred volumes, each a thousand pages long, in type so small as to be barely legible.” LEGO robot to make sucrose gradients.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

MARCH 26, 2023

Link Experimental Tests of the Virtual Circular Genome Model for Nonenzymatic RNA Replication. Link U1 snRNP increases RNA Pol II elongation rate to enable synthesis of long genes. Link A DNA tumor virus globally reprograms host 3D genome architecture to achieve immortal growth. Link Probing metabolism in an E. Mimoso C.A.

DNA 52

DNA Engineering RNA Science 52

Codon

APRIL 23, 2023

Most people would take the two CRISPR gene-editing components (a Cas9 protein and guide RNA), package them up inside of a virus, and then inject the viruses into the skulls of mice. Unfortunately, they can also trigger immune responses, and they are not super efficient at gene-editing some parts of the brain.

Vaccine 52

Vaccine DNA Virus Engineering 52

Codon

APRIL 23, 2023

Most people would take the two CRISPR gene-editing components (a Cas9 protein and guide RNA), package them up inside of a virus, and then inject the viruses into the skulls of mice. Unfortunately, they can also trigger immune responses, and they are not super efficient at gene-editing some parts of the brain.

Vaccine 52

Vaccine DNA Virus Engineering 52