Drug Discovery World

SEPTEMBER 14, 2023

Europe has one of the highest rates of bladder cancer in the world 1 , with more than 203,000 patients diagnosed in 2020 alone 2. Prognostic value and clinical significance of FGFR genomic alterations (GAs) in metastatic urothelial cancer patients. Expert Review of Clinical Pharmacology. J Clin Med. 2022;11(15): 4483.

Treatment 130

Treatment Clinical Pharmacology FDA Approval Therapies 130

Drug Target Review

MAY 7, 2024

In 2020, 78 percent of orphan drugs and biologics approved were targeted therapies. At Debiopharm, he has overseen both preclinical and clinical pharmacology of assets from phase I to III.

Disease 59

Disease Clinical Trials Clinical Pharmacology Trials 59

The Pharma Data

MAY 2, 2022

Data from the completed studies of zuranolone in the LANDSCAPE and NEST clinical development programs, including data from the ongoing open-label SHORELINE Study in MDD, as well as data from the completed clinical pharmacology studies, will comprise the full submission package. Food & Drug Administration.

Treatment 52

Treatment Clinical Pharmacology Drugs Biosimilars 52

The Pharma Data

NOVEMBER 8, 2020

9, 2020 00:00 UTC. HK) (“Pharmaron”), a fully integrated contract research and manufacturing organization offering laboratory, CMC and clinical development services for the life science industry, announced today that it has acquired 100% of the equity of Absorption Systems for up to US$137.5 Limited (Stock Code: 300759.SZ/3759.HK)

Clinical Pharmacology 40

Clinical Pharmacology Laboratories Science Pharmaceuticals 40

Metabolite Tales Blog

JULY 5, 2023

With metabolic stability in mind, we take a look at the metabolism of some FDA approved synthetic macrocyclic drugs, and a few of those that were/are in clinical development where metabolism data was available. link] [13] A user’s guide to lorlatinib. Nagasaka et al., Critical Reviews in Oncology/Hematology, 151, 102969, [link]. [16]

Metabolic Stability 52

Metabolic Stability Drugs FDA Approval Treatment 52

Metabolite Tales Blog

JULY 5, 2023

With metabolic stability in mind, we take a look at the metabolism of some FDA approved synthetic macrocyclic drugs, and a few of those that were/are in clinical development where metabolism data was available. link] [13] A user’s guide to lorlatinib. Nagasaka et al., Critical Reviews in Oncology/Hematology, 151, 102969, [link]. [16]

Metabolic Stability 52

Metabolic Stability Drugs FDA Approval Treatment 52

Agency IQ

SEPTEMBER 15, 2023

However, the Coronavirus Aid, Relief, and Economic Security (CARES) Act) of 2020 included provisions to overhaul OTC drug regulation. FDA’s clinical pharmacology analysis challenged previous in vitro estimates of bioavailability for orally administered phenylephrine. The two sides saw nearly every finding in a different light.

Science 40

Science FDA Clinical Trials Pharmacy 40