The Pharma Data

DECEMBER 2, 2020

Centers for Disease Control and Prevention. Centers for Disease Control and Prevention. © 2020 HealthDay. Posted: December 2020. Below are newsworthy items compiled by the Healthday staff: CDC To Shorten Recommended Quarantine Period. The antibodies suggest exposure to the new coronavirus or one very similar to it.

Virus 52

Virus Disease Research 52

Drug Target Review

AUGUST 11, 2023

In a new development, a recent paper published in Biology Methods & Protocols by Oxford University Press has highlighted a promising avenue for enhancing vaccine efficacy against infectious pathogens like the COVID-19 virus. Since December 2019, SARS-CoV-2 (COVID-19) infection has become a worldwide urgent public health concern.

Vaccine 98

Vaccine Immune Response Bioinformatics Virus 98

The Pharma Data

SEPTEMBER 4, 2020

The main test used to diagnose coronavirus is so sensitive it could be picking up fragments of dead virus from old infections, scientists say. He believes the detection of traces of old virus could partly explain why the number of cases is rising while hospital admissions remain stable. Image copyright. Getty Images.

Virus 52

Virus Hospitals Disease Research 52

Broad Institute

JANUARY 30, 2024

Bhattacharyya wears many coats today, splitting his time between the Broad and the infectious disease ward at MGH, where a diagnostic method he developed at Broad is now being tested to see if it helps patients quickly receive the best antibiotics for their infections.

Hospitals 137

Hospitals Virus Medical Schools Science 137

The Pharma Data

AUGUST 3, 2021

The drug, which has undergone several clinical trials for human conditions but has not yet received approval to treat humans, inhibited the replication of SARS-CoV-2, the virus that causes COVID-19, in human cell cultures and in a mouse model, leading to much lower viral loads. The research team, including scientists from the U.S.

Virus 52

Virus Clinical Trials Drugs Laboratories 52

The Pharma Data

DECEMBER 29, 2020

Experts believe brain-related effects may be tied to the body’s immune response to the virus and possibly to vascular problems or surges of inflammation caused by the disease. WHO is working with scientists around the world to “better understand any and all changes to the virus” and their impact, he said.

Virus 52

Virus Hospitals Immune Response Doctors 52

The Pharma Data

DECEMBER 21, 2020

The team at the Walter Reed Army Institute of Research is checking genetic sequences of the mutated virus variant posted online by British researchers, CNN reported. Centers for Disease Control and Prevention. © 2020 HealthDay. Posted: December 2020. The CDC said more than 190.4 million doses to 45.3 million as of Nov.

Vaccine 52

Vaccine Packaging Laboratories Virus 52

The Pharma Data

NOVEMBER 18, 2020

Antimicrobial resistance occurs when microorganisms resist the effects of medications, making infections harder to treat and increasing the risk of disease spread, severe illness and death. HIV drug resistance is caused by changes in the genetic structure of HIV that affects the ability of drugs to block the replication of the virus.

Laboratories 52

Laboratories Therapies Virus Government 52

The Pharma Data

NOVEMBER 17, 2020

17, 2020 — From 2009 to 2018, there were increases in diseases-of-despair diagnoses, according to a study published online Nov. Diagnoses related to alcohol misuse, substance misuse, and suicide ideation/behaviors were defined as diseases of despair. © 2020 HealthDay. Posted: November 2020. TUESDAY, Nov.

Disease 52

Disease Virus Research Drugs 52

The Pharma Data

DECEMBER 31, 2020

Monthly News Roundup – December 2020. In studies, the vaccines were found to be 94% to 95% effective in preventing COVID-19 disease. The messenger RNA (mRNA) vaccines encode a form of the spike (S) protein of SARS-CoV-2 virus. The partial piece of the spike protein cannot cause COVID-19 disease.

FDA Approval 52

FDA Approval Vaccine FDA Treatment 52

The Pharma Data

DECEMBER 30, 2020

The year 2020 will certainly go down in history as the year of COVID-19. Gilead Sciences Makes Multiple Bets : When Gilead Sciences wasn’t working on remdesivir in COVID-19, the company seemed to be constantly flexing its M&A muscle over the course of 2020. It began in May with the $4.9

Science 52

Science Disease Pharmaceuticals Treatment 52

The Pharma Data

MARCH 13, 2022

People who gained immunity – either through vaccination or exposure – against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen’s omicron variant. Singapore biotechnology company. population.

Virus 52

Virus Immune Response Vaccine Research 52

Codon

AUGUST 26, 2024

When COVID-19 emerged in 2019, by contrast, mRNA vaccines developed by Pfizer and Moderna took just 326 days from the initial sequencing of the virus to gaining approval for emergency use. These drugs would be ideal tools to bridge the wait for a vaccine against a quickly-spreading virus.

RNA 85

RNA Virus DNA Vaccine 85

Drug Target Review

OCTOBER 26, 2023

1 Adeno-associated virus (AAV) vectors are the leading platform for in vivo gene delivery for the treatment of various human diseases. It has been well established that exposure to wild-type AAV results in priming of the immune system against the virus. Nature 578 , 229-236 (2020). References Doudna JA. Ylä-Herttuala S.

Engineering 105

Engineering Virus Therapies Immune Response 105

The Pharma Data

NOVEMBER 3, 2020

Centers for Disease Control and Prevention study collected data on more than 400,000 symptomatic women aged 15 to 44, of whom more than 23,000 were pregnant. ” Prime Minister Boris Johnson also had the virus in the spring. © 2020 HealthDay. Posted: November 2020. He was admitted to the hospital, but recovered.

Hospitals 52

Hospitals Laboratories Doctors Virus 52

The Pharma Data

MARCH 3, 2022

Today’s decision is a pivotal next step in our path towards potential regulatory approval for our maternal RSV vaccine candidate and is an important milestone in our efforts to help address the detrimental impact RSV disease has on infants,” said Kathrin U. Burden of RSV RSV is a contagious virus and a common cause of respiratory illness.

Virus 52

Virus Vaccine Clinical Trials Trials 52

Drug Target Review

JANUARY 26, 2024

These ACE2-coated particles could be tested as an anti-viral therapeutic, and as sensors for detecting virus particles. They also investigated the placement of ACE2 proteins onto nanoparticles for possible applications in rapid virus detection or infection treatment. 2020 March 30 [2024 January 22]; 581:215-220.

Production 114

Production DNA Virus Protein Expression 114

The Pharma Data

DECEMBER 2, 2020

3, 2020 09:00 UTC. MTX-COVAB was also found to have virus neutralizing potency (IC50= 40pM), which is comparable or better to that of the leading antibody therapies in development, and cross-neutralizes all clinically relevant virus mutants. Memo Therapeutics AG is a private company located in Bio-Technopark Zurich, Switzerland.

Disease 52

Disease Virus Treatment Therapies 52

The Pharma Data

DECEMBER 5, 2020

5, 2020 — A pair of new gene therapies promise a potentially lasting cure for sickle cell disease by subtly altering the genetic information in patients’ bone marrow cells, researchers report. Lewis Hsu, chief medical officer of the Sickle Cell Disease Association of America. SATURDAY, Dec.

Therapies 52

Therapies Disease Medical Schools Virus 52

The Pharma Data

APRIL 14, 2021

The product’s early Marek’s disease onset of immunity from five days of age provides full protection of broilers, layers and breeders against the most virulent Marek’s disease virus strains. Its purpose is to provide poultry producers with cutting-edge technology in terms of Marek’s disease protection.

Vaccine 52

Vaccine Disease Virus Engineering 52

The Pharma Data

DECEMBER 10, 2020

The FDA said Thursday that it has developed a test for COVID-19 in fecal matter, in an attempt to prevent the disease from being inadvertently transmitted during fecal transplantation. We know now that the viral RNA is found in stool and infectious virus as well. 1, 2019, until effective screening methods are implemented.”.

FDA 52

FDA Laboratories RNA Virus 52

The Premier Consulting Blog

JUNE 18, 2023

One exciting application of these technologies is the use of in silico trials in the development of novel therapies for rare diseases. However, with rare diseases there may be no available treatments that could serve as SoC or active control in a clinical trial and assigning patients to placebo may be unethical.

Drug Development 52

Drug Development Disease Clinical Trials Drugs 52

Broad Institute

MAY 30, 2023

By Andrea Tamayo May 30, 2023 Credit: Allison Dougherty, Broad Communications Isabella Teixeira-Soldano studies single cells to better understand disease progression. Our hope is that studying changes in gene expression will lead to a better understanding of the progression of these diseases and better ways of treating them.

Research 89

Research Medical Schools Doctors Science 89

The Pharma Data

DECEMBER 22, 2020

22, 2020 — A new study may prove reassuring for expectant moms: Pregnant women who are infected with COVID-19 during their third trimester appear unlikely to pass the infection to their fetuses. Researchers evaluated the levels of virus in respiratory, blood and placental tissue samples. TUESDAY, Dec.

Virus 52

Virus Vaccine Disease Hospitals 52

NIH Director's Blog: Drug Development

MARCH 18, 2021

With support from a 2020 NIH Director’s Pioneer Award, Veesler will study members of the order Chiroptera. These days, the Veesler lab has been hard at work to understand SARS-CoV-2 and the human immune response to the virus. 2020 Apr 16;181(2):281-292.e6. Or, more colloquially, bats. Veesler says bats are remarkable creatures.

Virus 52

Virus Immune Response Clinical Trials Treatment 52

The Pharma Data

DECEMBER 15, 2020

A healthy immune system defends the body against disease and other conditions. Autoimmune disease impacts different parts of the body, weakening functionality. Researchers are aware of more than 80 diseases that occur when the immune system attacks the body’s own organs, tissues and cells. It may be life-threatening.

Disease 52

Disease Clinical Trials Small Molecule Trials 52

The Pharma Data

JULY 21, 2021

Valneva SE (Nasdaq: VALN; Euronext Paris: VLA), a specialty vaccine company focused on the development and commercialization of prophylactic vaccines for infectious diseases with significant unmet medical need, and Pfizer Inc. Valneva and Pfizer entered into a collaboration agreement in April 2020 to co-develop VLA15 2. About VLA15.

Vaccine 52

Vaccine Disease Trials Protein Expression 52

The Pharma Data

AUGUST 15, 2021

Food and Drug Administration (FDA) has granted Fast Track designation to VTX-801, Vivet’s clinical-stage gene therapy for the treatment of Wilson Disease – a rare, genetic disorder that reduces the ability of the liver and other tissues to regulate copper levels, causing severe hepatic damage, neurological symptoms, and potentially death.

Disease 52

Disease FDA Treatment Clinical Trials 52

DrugBaron

NOVEMBER 9, 2020

The first death unequivocally caused by COVID was reported to the world on January 11 th 2020 – that’s just 303 days ago (even if it feels like a lifetime away). After all, the threat posed by cancer, heart disease, stroke, diabetes and Alzheimer’s, if less immediate is no less severe. But that cannot be the whole answer.

Vaccine 100

Vaccine Pharmaceutical Companies Government Pharmaceuticals 100

New Drug Approvals

DECEMBER 26, 2022

1 heavy chain (1-456) (human vh (homo sapiens ighv1-69*01(ighd)-ighj4*01 (90.1%)) (8.8.19) (1-126) -homo sapiens ighg1*03 Immunoglobulin g1, anti-(human respiratory syncytial virus fusion protein)(human monoclonal med18897.gamma.1-chain), 2020) Dosage regimens for and compositions including anti-rsv antibodies. 2020/0347120 A1).

Virus 52

Virus Clinical Trials Trials Disease 52

The Pharma Data

OCTOBER 29, 2020

30, 2020 /PRNewswire/ — Eli Lilly and Company (NYSE: LLY) and Incyte (NASDAQ: INCY) announced today new data for baricitinib (marketed as OLUMIANT ® ) will be presented at the annual Fall Clinical Dermatology meeting taking place virtually October 29-November 1, 2020. INDIANAPOLIS , Oct.

Therapies 52

Therapies Treatment Disease Clinical Trials 52

Codon

AUGUST 27, 2024

Doctors in training are told that when they hear hoofbeats, they should think horses, not zebras; rare diseases are the exception, not the rule. Sometimes, though, novel diseases do emerge, and as COVID-19 demonstrated, they can surprise us. This is the third essay of four in our pandemic mini-issue.

DNA 84

DNA Laboratories Hospitals Virus 84

The Pharma Data

NOVEMBER 18, 2020

18, 2020 — Children should be included in clinical trials for a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine at the earliest stages, according to a letter from the president of the American Academy of Pediatrics (AAP), on behalf of more than 67,000 pediatricians and pediatric medical and surgical subspecialists. .”

Vaccine 52

Vaccine Trials Immune Response Virus 52

The Pharma Data

DECEMBER 31, 2020

31, 2020 — Blood vessel damage and inflammation in the brains of deceased COVID-19 patients suggest the damage is not caused by the virus, but the body’s immune response to it. The researchers saw no signs of the virus in the tissue samples, which they said may mean that the damage was not caused by the virus itself.

Immune Response 52

Immune Response Virus Doctors Research 52

The Pharma Data

DECEMBER 22, 2020

22, 2020 — For Americans who are worried about the new coronavirus variant that is circulating in Britain, experts in the United States urge everyone to stay calm. “But again, the low mutation rate makes the adaptation of this virus to a vaccine less likely.” TUESDAY, Dec. ” What is a variant?

Virus 52

Virus Vaccine Immune Response Treatment 52

The Pharma Data

DECEMBER 21, 2020

21, 2020 — The new coronavirus variant in the United Kingdom that appears to spread faster is being studied by U.S. The team at the Walter Reed Army Institute of Research is checking genetic sequences of the mutated virus variant posted online by British researchers, CNN reported. © 2020 HealthDay. Posted: December 2020.

Research 52

Research Vaccine Virus Disease 52

Drug Target Review

SEPTEMBER 28, 2023

They needed reference materials for the disease in order to develop and validate diagnostic tests. For security reasons, at the time COVID-19 had to be grown in BSL-3 labs, which can be dangerous because they were handling the live virus. These are synthetic, not the live virus, so do not pose a risk of infection.

DNA 116

DNA Organic Chemistry Science Virus 116