The Pharma Data

DECEMBER 29, 2020

Experts believe brain-related effects may be tied to the body’s immune response to the virus and possibly to vascular problems or surges of inflammation caused by the disease. WHO is working with scientists around the world to “better understand any and all changes to the virus” and their impact, he said.

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The Pharma Data

NOVEMBER 18, 2020

HIV drug resistance is caused by changes in the genetic structure of HIV that affects the ability of drugs to block the replication of the virus. Between 2004 and 2020, 57 countries implemented surveys of HIV drug resistance using WHO-recommended methods (see map below), and 17 countries have plans to conduct surveys. among adults and.

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The Pharma Data

DECEMBER 2, 2020

It’s not known if these infections were in people who caught the virus in other countries, or whether the infections led to wider community transmission, said the authors of the study that has been accepted for publication in the journal Clinical Infectious Diseases. © 2020 HealthDay. Posted: December 2020.

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The Pharma Data

DECEMBER 21, 2020

The team at the Walter Reed Army Institute of Research is checking genetic sequences of the mutated virus variant posted online by British researchers, CNN reported. © 2020 HealthDay. Posted: December 2020. The new coronavirus variant in the UK that appears to spread faster is being studied by U.S. All rights reserved.

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The Pharma Data

MARCH 13, 2022

People who gained immunity – either through vaccination or exposure – against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen’s omicron variant. population. The samples were stored after the researchers measured the T cell response.

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The Pharma Data

AUGUST 3, 2021

The drug, which has undergone several clinical trials for human conditions but has not yet received approval to treat humans, inhibited the replication of SARS-CoV-2, the virus that causes COVID-19, in human cell cultures and in a mouse model, leading to much lower viral loads. The research team, including scientists from the U.S.

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The Pharma Data

JANUARY 11, 2021

Food and Drug Administration said the test from California company Curative could produce false negatives, leading people with the virus to unknowingly spread it, the Associated Press reported. Last week, the U.S. The test is used by at least three of the largest U.S. cities, the AP reported.

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PLOS: DNA Science

MAY 16, 2024

A Novel Virus Appears In retrospect, everything unfolded with astonishing speed. A few days after New Years, 2020, I heard BBC News report the first cases, in China. Whenever and wherever the virus emerged, CDC officially alerted clinicians to the new, deadly respiratory illness on January 8, 2020.

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The Pharma Data

DECEMBER 31, 2020

Monthly News Roundup – December 2020. The messenger RNA (mRNA) vaccines encode a form of the spike (S) protein of SARS-CoV-2 virus. The vaccine teaches the cells to make a piece of the spike protein, which triggers an immune response to help prevent illness if later exposed to the virus. Posted: December 2020.

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Drug Target Review

OCTOBER 26, 2023

1 Adeno-associated virus (AAV) vectors are the leading platform for in vivo gene delivery for the treatment of various human diseases. It has been well established that exposure to wild-type AAV results in priming of the immune system against the virus. Nature 578 , 229-236 (2020). Nature Reviews Genetics 21 , 255-272 (2020).

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The Pharma Data

DECEMBER 30, 2020

The year 2020 will certainly go down in history as the year of COVID-19. Gilead Sciences Makes Multiple Bets : When Gilead Sciences wasn’t working on remdesivir in COVID-19, the company seemed to be constantly flexing its M&A muscle over the course of 2020. It began in May with the $4.9

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Drug Target Review

AUGUST 11, 2023

In a new development, a recent paper published in Biology Methods & Protocols by Oxford University Press has highlighted a promising avenue for enhancing vaccine efficacy against infectious pathogens like the COVID-19 virus. The role of extracellular vesicles in COVID-19 virus infection [Internet]. Available from: [link]

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Codon

AUGUST 26, 2024

When COVID-19 emerged in 2019, by contrast, mRNA vaccines developed by Pfizer and Moderna took just 326 days from the initial sequencing of the virus to gaining approval for emergency use. These drugs would be ideal tools to bridge the wait for a vaccine against a quickly-spreading virus.

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Drug Target Review

JANUARY 26, 2024

These ACE2-coated particles could be tested as an anti-viral therapeutic, and as sensors for detecting virus particles. They also investigated the placement of ACE2 proteins onto nanoparticles for possible applications in rapid virus detection or infection treatment. 2020 March 30 [2024 January 22]; 581:215-220.

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The Pharma Data

MARCH 3, 2022

If approved by the FDA, this maternal immunization has the potential to be the first vaccine candidate to help protect infants in their vulnerable first months of life from disease caused by this highly-contagious virus. Burden of RSV RSV is a contagious virus and a common cause of respiratory illness. Pfizer Inc.

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Broad Institute

JANUARY 30, 2024

He has also emerged in recent years as a skilled and relatable science communicator, renowned for his efforts at Broad and beyond during the COVID-19 pandemic to unpack the fast-moving research on the new virus in an accessible way and give practical advice about masking, vaccines, and other public health measures.

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NIH Director's Blog: Drug Development

MARCH 18, 2021

With support from a 2020 NIH Director’s Pioneer Award, Veesler will study members of the order Chiroptera. These days, the Veesler lab has been hard at work to understand SARS-CoV-2 and the human immune response to the virus. 2020 Apr 16;181(2):281-292.e6. Or, more colloquially, bats. Veesler says bats are remarkable creatures.

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The Pharma Data

DECEMBER 10, 2020

We know now that the viral RNA is found in stool and infectious virus as well. Therefore, Carlson said, “we advised no use of fecal donations from after Dec. 1, 2019, until effective screening methods are implemented.”. There were no methods for testing for COVID in stool,” he said. “We Infection in the GI tract is likely.”

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The Pharma Data

DECEMBER 7, 2020

7, 2020 — Scientists say they may be getting closer to creating a universal flu vaccine. In an early-stage clinical trial with 65 volunteers in the United States, an experimental vaccine triggered strong immune responses to a wide range of flu virus strains and subtypes. © 2020 HealthDay. Posted: December 2020.

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The Pharma Data

DECEMBER 30, 2020

30, 2020 — The first recorded case of a faster-spreading variant of the new coronavirus has been detected in a 20-year-old man in Colorado, Gov. The young man carries a variant of the virus that is thought to be more contagious — but not more lethal — than variants previously circulating globally this year.

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The Pharma Data

DECEMBER 31, 2020

31, 2020 — Blood vessel damage and inflammation in the brains of deceased COVID-19 patients suggest the damage is not caused by the virus, but the body’s immune response to it. The researchers saw no signs of the virus in the tissue samples, which they said may mean that the damage was not caused by the virus itself.

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NIH Director's Blog: Drug Discovery

NOVEMBER 5, 2020

Because SARS-CoV-2 is so highly infectious, basic researchers without access to specially designed biosafety facilities may be limited in their ability to study the virus. While the quantum dots may bind and enter human cells just like the virus, they can’t cause an infection. 2020 Sep 22;14(9):12234-12247.

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The Pharma Data

JANUARY 6, 2021

The announcement, following a $98 million IPO in October 2020, comes as the company advances several programs through its pipeline. In addition to its lead program, which began Phase I testing in 2020, the company expects to nominate three clinical candidates in 2021.

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The Pharma Data

NOVEMBER 18, 2020

18, 2020 — Children should be included in clinical trials for a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine at the earliest stages, according to a letter from the president of the American Academy of Pediatrics (AAP), on behalf of more than 67,000 pediatricians and pediatric medical and surgical subspecialists. .”

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The Pharma Data

DECEMBER 22, 2020

22, 2020 — A new study may prove reassuring for expectant moms: Pregnant women who are infected with COVID-19 during their third trimester appear unlikely to pass the infection to their fetuses. Researchers evaluated the levels of virus in respiratory, blood and placental tissue samples. ” © 2020 HealthDay.

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The Pharma Data

DECEMBER 22, 2020

22, 2020 — For Americans who are worried about the new coronavirus variant that is circulating in Britain, experts in the United States urge everyone to stay calm. “But again, the low mutation rate makes the adaptation of this virus to a vaccine less likely.” ” © 2020 HealthDay. TUESDAY, Dec.

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The Pharma Data

DECEMBER 16, 2020

16, 2020 — A World Health Organization team of experts will examine samples and medical data from China to try to find out where the new coronavirus first made the leap from animals to people. © 2020 HealthDay. . © 2020 HealthDay. Posted: December 2020. WHO Team Seeks to Pinpoint Source of COVID-19. WEDNESDAY, Dec.

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New Drug Approvals

DECEMBER 26, 2022

1 heavy chain (1-456) (human vh (homo sapiens ighv1-69*01(ighd)-ighj4*01 (90.1%)) (8.8.19) (1-126) -homo sapiens ighg1*03 Immunoglobulin g1, anti-(human respiratory syncytial virus fusion protein)(human monoclonal med18897.gamma.1-chain), 2020) Dosage regimens for and compositions including anti-rsv antibodies. 2020/0347120 A1).

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The Pharma Data

DECEMBER 23, 2020

23, 2020 — A COVID-19 outbreak in Antarctica means that the new coronavirus is now spreading on every continent. Until then, Antarctica had been the only continent that was free of the virus, CNN reported. © 2020 HealthDay. Posted: December 2020. WEDNESDAY, Dec. CNN Article. All rights reserved. More News Resources.

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The Pharma Data

DECEMBER 17, 2020

17, 2020 — As a rule, COVID-19 spreads rapidly in most groups, but new research suggests that schools and day care centers appear to be the exception. ” But for schools to be safe, they need a lot of help, support and equipment to keep the virus from spreading, Hobbs said. © 2020 HealthDay. . © 2020 HealthDay.

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The Pharma Data

DECEMBER 15, 2020

15, 2020 — The U.S. Preventive Services Task Force (USPSTF) concludes that screening adults and adolescents at increased risk for hepatitis B virus (HBV) infection has moderate net benefit. © 2020 HealthDay. Posted: December 2020. Professional. USPSTF Recommends Hep B Screen for At-Risk Teens, Adults. TUESDAY, Dec.

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The Pharma Data

DECEMBER 21, 2020

21, 2020 — The new coronavirus variant in the United Kingdom that appears to spread faster is being studied by U.S. The team at the Walter Reed Army Institute of Research is checking genetic sequences of the mutated virus variant posted online by British researchers, CNN reported. © 2020 HealthDay. Posted: December 2020.

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The Pharma Data

NOVEMBER 16, 2020

16, 2020 — Scientists are reporting early success with an experimental herpes vaccine that uses a genetically modified version of the virus. The gene edit prevents the virus from performing its normal evasive maneuver: hiding out in nervous system cells in order to elude the immune system. © 2020 HealthDay.

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The Pharma Data

DECEMBER 2, 2020

3, 2020 17:00 UTC. Under his leadership, the Company has demonstrated the potential of virus-based immunotherapies and developed world class innovative therapies that could be game-changers in the field of cancer treatment. Sandrine has been Chief Financial Officer of Institut Mérieux since March 2020. Trangene’s Invir.IO

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The Pharma Data

DECEMBER 23, 2020

While the overall understanding of the condition is as novel as the virus that causes it, a recent survey from the U.K.’s This is proving very difficult, however, for the ever-expanding group of people dealing with the chronic and debilitating symptoms of what is commonly being called “Long Haul COVID” or “Long COVID.”.

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The Pharma Data

DECEMBER 28, 2020

28, 2020 — Travelers flying to the United States from the United Kingdom will now need a negative COVID-19 test no more than 72 hours before leaving Britain, the U.S. The test is needed to guard against the spread of a new form of the virus found in the United Kingdom that may be 70 percent more contagious than other forms of COVID-19.

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The Pharma Data

JUNE 25, 2021

The outcome confirms that only one single case was attributable to the original SARS-CoV-2 virus. “In addition, the variant-rich environment underlines the importance of developing next-generation vaccines as new virus variants continue to emerge.” More than half of the cases (57%) were caused by Variants of Concern.

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