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How big data analytics can make personalised care a reality

Drug Discovery World

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care. Given below is a summary of these practices along with some examples of real-world applications.

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Can Global Genomic Surveillance Forecast the Next Pandemic?

PLOS: DNA Science

Had we grown complacent in a world freed from a list of once-deadly infectious diseases, thanks largely to vaccines and other public health measures? As soon as the initial RNA genome sequence of the pathogen that would be named SARS-CoV-2 was published, CDC and other organizations began developing diagnostic tests.

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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

The paper is also nearly two years old at this point; the preprint was published in August 2021. link ) INSPECTR is a diagnostic tool to detect tiny amounts of viral RNA at room temperature. link ) A phase I trial of a personalized neoantigen vaccine showed that they could boost T-cells and help fight off pancreatic tumors.

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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

The paper is also nearly two years old at this point; the preprint was published in August 2021. link ) INSPECTR is a diagnostic tool to detect tiny amounts of viral RNA at room temperature. link ) A phase I trial of a personalized neoantigen vaccine showed that they could boost T-cells and help fight off pancreatic tumors.

DNA 52
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The Codon Guide to Synthetic Biology

Codon

Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Journal of Molecular Biology (2021). Nature (2021). Nature Biotechnology (2021). Nature Reviews Methods Primers (2021). Annual Review of Biochemistry (2021). & Charpentier E. Nature (2016).

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