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Lilly Delivers Strong Second-Quarter 2021 Financial Results, Updates 2021 Financial Guidance

The Pharma Data

Revenue in the second quarter of 2021 increased 23 percent, driven by volume growth of 22 percent. – Revenue from all key products grew in the quarter and 2021 year-to-date. . – Revenue from all key products grew in the quarter and 2021 year-to-date. – 2021 EPS guidance updated to be in the range of $6.73

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The challenges and trends of cell & gene therapies 

Drug Discovery World

Unsurprisingly, oncology remains the biggest focus for cell and gene therapy developers, accounting for 52% of clinical activity in 2021, according to ARM’s Regenerative Medicine: Disrupting the Status Quo report. Cancer is king . Despite this the industry is still expanding. New indications .

Therapies 130
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Organ-on-a-chip models in drug development

Drug Discovery World

Testing new modality drugs poses additional challenges The drug development pipeline is no longer predominantly composed of small molecule drugs. 2021) 6 evaluated the role of SPTBN1 in diet-induced liver diseases and cancer. Drug-induced liver injury (DILI) is the most common cause of acute liver failure in the western world 4.

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Organ-on-a-chip models in drug development

Drug Discovery World

Testing new modality drugs poses additional challenges The drug development pipeline is no longer predominantly composed of small molecule drugs. 2021) 6 evaluated the role of SPTBN1 in diet-induced liver diseases and cancer. Drug-induced liver injury (DILI) is the most common cause of acute liver failure in the western world 4.

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Pfizer and BioNTech Announce Data from Preclinical Studies of mRNA-based Vaccine Candidate Against COVID-19

The Pharma Data

Immunization of non-human primates (rhesus macaques) with BNT162b2, a nucleoside-modified messenger RNA (modRNA) candidate that expresses the SARS-CoV-2 spike glycoprotein, resulted in strong anti-viral effects against an infectious SARS-CoV-2 challenge. producing CD8+ T cell responses, which is thought to promote an anti-viral effect.

Vaccine 52
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Defense-Forward Biosecurity

Codon

When doctors sequenced the DNA and RNA found in Alice’s blood and synovial fluid—the liquid that surrounds and lubricates joints—they found abnormally low levels of genes encoding iron-storing proteins and high levels of epidermal growth factor receptor RNA.

DNA 84
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BioNTech announces first patient dosed in Phase 2 clinical trial of mRNA-based BNT111 in patients with advanced melanoma

The Pharma Data

BNT111 is the lead product candidate from BioNTech’s FixVac platform that targets a fixed combination of mRNA-encoded, tumor-associated antigens with the objective of triggering a strong and precise immune response against cancer and is fully owned by BioNTech. These results were published in Nature in July 2020.