2022 - Drug Discovery Digest

The 2022 European drought: What was the role of climate change?

Science Daily: Pharmacology News

OCTOBER 21, 2024

The drought that lasted through the summer of 2022 was especially intense and caused the soil in many regions of Europe to dry out substantially. Public discussions about the causes repeatedly broached the question of the extent to which climate change intensified this extreme weather event.

Research

U.S. Maternal Deaths Declined in 2022

Drugs.com

MAY 2, 2024

THURSDAY, May 2, 2024 -- The number of American women who died at or soon after childbirth declined significantly in 2022, the latest government data shows, but the rate is still higher than pre-pandemic levels.The report from the U.S. National.

Government

U.S. Measles Cases Reach 125, Surpassing Recent Peak in 2022

Drugs.com

APRIL 22, 2024

government data shows.That is more cases than were reported in all of 2022, the most recent annual peak. MONDAY, April 22, 2024 -- Measles infections continue to spread across the country, with 125 cases now reported in 18 states, new U.S.

Government

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U.S. Suicide Numbers Hit New Record High in 2022

Drugs.com

NOVEMBER 29, 2023

suicide numbers reached a grim new high in 2022. WEDNESDAY, Nov. 29, 2023 -- U.S. The increase was most acute among women over the age of 24, according to provisional data from the U.S. Centers for Disease Control and Prevention. Overall, almost.

Disease

Massive 2022 eruption reduced ozone layer levels

Science Daily: Pharmacology News

NOVEMBER 20, 2023

The Hunga Tonga-Hunga Ha'apai volcano changed the chemistry and dynamics of the stratosphere in the year following the eruption, leading to unprecedented losses in the ozone layer of up to 7% over large areas of the Southern Hemisphere.

Small Molecule of the Year – 2022

Drug Hunter

APRIL 20, 2023

We asked the global drug discovery community to nominate and vote on their favorite molecule from 2022, and the results are in. The 2022 winner, with the most overall votes across the ten finalist molecules , is BMS’ oral, deuterated allosteric TYK2 inhibitor, deucravacitinib, the first new treatment for plaque psoriasis in nearly a decade.

Small Molecule

Small Molecule Clinical Trials Trials Licensing

CAR-T for lupus: the ‘tip of the iceberg’ for cell therapy in autoimmune disease

BioPharma Drive: Drug Pricing

JANUARY 30, 2024

Since a landmark paper in 2022, drugmakers have begun nearly a dozen trials of cell therapies for lupus, with more set to start. Here’s why their efforts are worth watching.

Therapies

Therapies Disease Trials

How Earth's most intense heat wave ever impacted life in Antarctica

Science Daily: Pharmacology News

SEPTEMBER 4, 2024

An atmospheric river brought warm, moist air to the coldest and driest corner of the planet in 2022, pushing temperatures 70 degrees above average. A new study reveals what happened to Antarctica's smallest animals.

Global life expectancy to increase by nearly 5 years by 2050 despite geopolitical, metabolic, and environmental threats

Science Daily: Pharmacology News

MAY 17, 2024

years in females between 2022 and 2050. The latest findings forecast that global life expectancy will increase by 4.9 years in males and 4.2 Increases are expected to be largest in countries where life expectancy is lower, contributing to a convergence of increased life expectancy across geographies.

Disease

Brightest gamma-ray burst of all time came from the collapse of a massive star

Science Daily: Pharmacology News

APRIL 12, 2024

In 2022, astronomers discovered the brightest gamma-ray burst (GRB) of all time. Now, astronomers confirm that a 'normal' supernova, the telltale sign of a stellar collapse, accompanied the GRB. The team also looked for signatures of heavy elements like gold and platinum in the supernova.

A virus could help save billions of gallons of wastewater produced by fracking

Science Daily: Pharmacology News

APRIL 30, 2024

An estimated 168 billion gallons of wastewater -- or produced water -- is generated annually by the Permian Basin fracking industry, according to a 2022 report. The major waste stream has proved both difficult and costly to treat because of the chemical complexity of the water.

Virus

Massive merger: Study reveals evidence for origin of supermassive black hole at galaxy's center

Science Daily: Pharmacology News

SEPTEMBER 6, 2024

The study builds on recent observations from the Event Horizon Telescope (EHT), which captured the first direct image of Sgr A* in 2022.

Research

Investigating newly discovered hydrothermal vents at depths of 3,000 meters off Svalbard

Science Daily: Pharmacology News

JUNE 28, 2024

During a 2022 expedition of the MARIA S. Hydrothermal vents can be found around the world at the junctions of drifting tectonic plates. But there are many hydrothermal fields still to be discovered. MERIAN, the first field of hydrothermal vents on the 500-kilometer-long Knipovich Ridge off the coast of Svalbard was discovered.

More Women Underwent Surgical Sterilization After Fall of Roe v. Wade

Drugs.com

SEPTEMBER 11, 2024

Wade was overturned in 2022, rates of surgical sterilization rose in those states most affected by the decision, new research shows. WEDNESDAY, Sept. 11, 2024 -- As fears of the consequences of an unintended pregnancy rose after Roe v. Rates of.

Research

Fall of Roe v. Wade Has Made Access to Ob/Gyns Tougher in Many States: Report

Drugs.com

JULY 18, 2024

Wade in June 2022, even more women have struggled to find reproductive care, a new report warns.Issued Thursday by the Commonwealth Fund, the report shows that women living. THURSDAY, July 18, 2024 -- Ever since the Supreme Court overturned Roe v.

Stroke Rates Are Rising, Especially Among the Young

Drugs.com

MAY 23, 2024

THURSDAY, May 23, 2024 -- The rate at which Americans under the age of 65 suffered a stroke rose by about 15% between 2011 and 2022, new government data shows.That was true even among the young: The rate of stroke jumped 14.6% among people ages 18.

Government

Almost All Counterfeit Oxycontin Pills Contain Fentanyl

Drugs.com

MAY 7, 2024

TUESDAY, May 7, 2024 -- Lab tests of counterfeit oxycodone (Oxycontin) pills seized by police in Rhode Island in 2022 found 99.3% also contained dangerous fentanyl. It was typically mixed with another potentially deadly drug, xylazine.Both.

Drugs

Video gaming improves mental well-being, landmark study finds

Science Daily: Pharmacology News

AUGUST 27, 2024

A pioneering study titled 'Causal effect of video gaming on mental well-being in Japan 2020-2022,' published in Nature Human Behaviour, has conducted the most comprehensive investigation to date on the causal relationship between video gaming and mental well-being.

Research

Ketamine Use Is on the Rise in U.S.

Drugs.com

JANUARY 20, 2025

adults increased 40% between 2021 and 2022, researchers say.That follows a nearly 82% increase in. MONDAY, Jan. 20, 2025 -- Many more Americans are turning to ketamine for kicks, a new study reports.Recreational use of the anesthetic drug among U.S.

Research

Research Drugs

U.S. Infant Deaths Rose After Fall of Roe v. Wade

Drugs.com

OCTOBER 21, 2024

Wade, a new study shows.The Dobbs ruling, handed down in July of 2022. MONDAY, Oct. 21, 2024 -- The United States experienced a small but significant rise in infant deaths in the months following the U.S. Supreme Court's decision overturned Roe v.

Big Rise in Emergencies Involving Synthetic Weed Among Kids, Adults

Drugs.com

MAY 8, 2024

poison centers regarding so-called synthetic cannabis jumped 88% between 2021 and 2022, as use of these legally sold products rose, research shows.Synthetic cannabis contain varying forms of the active. WEDNESDAY, May 8, 2024 -- Calls to U.S.

Production

Production Research

Humira leads ICER’s latest list of ‘unsupported’ price hikes

BioPharma Drive: Drug Pricing

DECEMBER 11, 2023

billion in 2022, according to the price watchdog’s latest yearly report. AbbVie’s blockbuster medicine topped a list of treatments that, combined, elevated U.S. healthcare spending by $1.3

Treatment

Holographic 3D printing has the potential to revolutionize multiple industries

Science Daily: Pharmacology News

OCTOBER 8, 2024

It builds on a method introduced in 2022 that described how sonochemical reactions in microscopic cavitations regions -- tiny bubbles -- create extremely high temperatures and pressure for trillionths of a second to harden resin into complex patterns. Researchers have developed a novel method of 3D printing that uses acoustic holograms.

Research

High Rates of Loneliness Seen Among Bisexual and Transgender People

Drugs.com

JUNE 20, 2024

adults from 2022 finds the highest rates of. THURSDAY, June 20, 2024 -- Transgender and bisexual adults have rates of loneliness that are much higher than that of cisgender and heterosexual people, new data shows.Federal health data on U.S.

Cancer mortality continues to drop despite rising incidence in women

Science Daily: Pharmacology News

JANUARY 16, 2025

The new findings show the cancer mortality rate declined by 34% from 1991 to 2022 in the United States, averting approximately 4.5 The American Cancer Society (ACS) today released Cancer Statistics, 2025, the organization's annual report on cancer facts and trends. million deaths.

Disease

Steady Rise in U.S. Cases of Tick-Borne Babesiosis Disease

Drugs.com

OCTOBER 9, 2024

9, 2024 -- Cases of a tick-borne parasitic disease have steadily increased in recent years, a new study shows.Rates of babesiosis increased an average 9% a year in the United States between 2015 and 2022, researchers reported in. WEDNESDAY, Oct.

Disease

Disease Research

Number of Americans With Type 2 Diabetes Jumped by 20% in a Decade

Drugs.com

AUGUST 22, 2024

21, 2024 -- Type 2 diabetes increased by nearly 20% in the United States between 2012 and 2022, with age, race, income level, obesity and lack of exercise all playing a role in the metabolic disease’s spread, a new study r. THURSDAY, Aug.

Rates of Anxiety, Depression Rising Among Americans, Especially the Young

Drugs.com

NOVEMBER 7, 2024

adults, especially younger folks, continues to rise, the latest federal data shows.Nearly 1 in every 5 (18.2%) adults reported anxiety issues in 2022, up from 15.6% THURSDAY, Nov. 7, 2024 -- Rates of anxiety and depression among U.S.

U.S. Births Continue to Fall, Dropping by 17% Since 2007

Drugs.com

AUGUST 20, 2024

births falling by 2% last year compared to 2022, continuing a decades-long decline.Overall, annual U.S. TUESDAY, Aug. 20, 2024 -- Final government data finds the number of U.S. birth numbers have fallen by 17% since peaking in 2007, according to.

Government

The heat index -- how hot it really feels -- is rising faster than temperature

Science Daily: Pharmacology News

MARCH 20, 2024

Researchers showed in 2022 that heat index calculations by NOAA based on analyses from the 1970s don't adequately reflect the heat stress humans feel during the extremes of heat and humidity accompanying climate change.

Research

U.S. Life Expectancy Rose Overall, But Overdose Deaths Still Set Records

Drugs.com

MARCH 21, 2024

THURSDAY, March 21, 2024 -- As the pandemic wound down, life expectancy in the United States began to bounce back in 2022, although deaths among children increased and drug overdose deaths continued to reach record highs, new government research.

Government

Government Research Drugs

Stigma, Shame Hit Many Gay Men Affected by Mpox Outbreak

Drugs.com

APRIL 19, 2024

FRIDAY, April 19, 2024 -- A British study finds that beyond the physical pain and turmoil of an mpox diagnosis, many of the mostly gay and bisexual men infected during the 2022 outbreak faced stigma, homophobia and shame. Mpox is spread largely.

Gross-to-Net Bubble Update: 2022 Pricing Realities at 10 Top Drugmakers

Drug Channels

JUNE 13, 2023

When rebates and discounts were factored in, brand-name drug prices again declined—or grew slowly—in 2022. But for now, the 2022 data provide fresh inconvenient facts for the drug pricing flat earthers (#DPFE). You can find links to each company’s data below. However, some companies had net price gains. See the second chart below.

Pharmaceuticals

Pharmaceuticals Drugs

In Mississippi, a Huge Jump in Cases of Babies Born With Syphilis

Drugs.com

SEPTEMBER 21, 2023

21, 2023 -- The United States is experiencing an alarming wave of congenital syphilis, and one southern state saw a 1,000% rise in babies born with the infection between 2016 and 2022. THURSDAY, Sept. The number of babies born with the infection in.

Bird Flu Is Spreading: What You Need To Know

Drugs.com

FEBRUARY 2, 2025

2, 2025 -- A rapidly-spreading H5N1 avian influenza, otherwise known as bird flu, has been devastating bird flocks and showing signs of spreading to other mammals.Since 2022, more than 147 million birds in the U.S. SUNDAY, Feb. have been affected.

NASA's Fermi finds new feature in brightest gamma-ray burst yet seen

Science Daily: Pharmacology News

JULY 25, 2024

In October 2022, astronomers were stunned by what was quickly dubbed the BOAT -- the brightest-of-all-time gamma-ray burst (GRB). Now an international science team reports that data from NASA's Fermi Gamma-ray Space Telescope reveals a feature never seen before.

International

International Science

Gross-to-Net Bubble Update: 2022 Pricing Realities at 10 Top Drugmakers (rerun)

Drug Channels

OCTOBER 4, 2023

When rebates and discounts were factored in, brand-name drug prices again declined—or grew slowly—in 2022. But for now, the 2022 data provide fresh inconvenient facts for the drug pricing flat earthers (#DPFE). You can find links to each company’s data below. However, some companies had net price gains. See the second chart below.

Pharmaceuticals

Pharmaceuticals Drugs

Poll Finds Many Young Workers Feeling Stressed, Isolated

Drugs.com

JUNE 14, 2024

The 2022 Work in America survey, conducted by the American Psychological Association (APA), found that young adults are. FRIDAY, June 14, 2024 -- Many younger workers feel stressed, isolated and unappreciated at their jobs, a new survey has found.

Diphtheria-Like Germ Can Be Passed Between People and Pets

Drugs.com

JUNE 13, 2024

The respiratory illnesses occurred in 2022 and 2023 and. THURSDAY, June 13, 2024 -- The first two cases of a diphtheria-like illness being transmitted in the United States between people and their pets have been reported in Utah and Colorado.

Homeless Americans' Death Rate Rises on Hot Days

Drugs.com

OCTOBER 15, 2024

15, 2024 -- As temperatures soar in some of America's hottest spots, death rates among local homeless people rise as well, new research shows.Data from 2015 through 2022 finds a big bump in deaths among unhoused people in Clark County. TUESDAY, Oct.

Research

More Than Half of Heat Deaths Can Be Blamed on Global Warming: Study

Drugs.com

OCTOBER 29, 2024

29, 2024 -- Researchers looking at the sweltering European summer of 2022 estimated that more than half of the heat-linked deaths occurring on the continent would not have happened if human-led climate change wasn't in place."Without. TUESDAY, Oct.

Research

Drug-Linked Infant Deaths Doubled in U.S. in 4 Years

Drugs.com

JUNE 5, 2024

WEDNESDAY, June 5, 2024 -- As an epidemic of drug abuse cuts it way through America, none are left unharmed, even the very young.New data finds that the rate of infants dying from drug-related reasons more than doubled between 2018 and 2022.In.

Drugs

U.S. Drowning Deaths Rising Again After Years of Decline

Drugs.com

MAY 14, 2024

More than 4,500 people died from drowning each year in 2020 through 2022, 500 more per. TUESDAY, May 14, 2024 (HeathDay News) -- Following decades of declines, drowning deaths are once again climbing in the United States, new government data shows.

Government

Early Deaths From Heart Disease Rising in Rural U.S.

Drugs.com

NOVEMBER 12, 2024

rural areas by about 21% between 2010 and 2022, researchers report in the Journal. TUESDAY, Nov. 11, 2024 -- More people in rural America are dying from heart disease, a new study says.Heart disease deaths increased among 25- to 64-year-olds in U.S.

Disease

Disease Research

The 2022 European drought: What was the role of climate change?

U.S. Maternal Deaths Declined in 2022

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Trending Sources

U.S. Measles Cases Reach 125, Surpassing Recent Peak in 2022

Webinars

U.S. Suicide Numbers Hit New Record High in 2022

Massive 2022 eruption reduced ozone layer levels

Small Molecule of the Year – 2022

CAR-T for lupus: the ‘tip of the iceberg’ for cell therapy in autoimmune disease

How Earth's most intense heat wave ever impacted life in Antarctica

Global life expectancy to increase by nearly 5 years by 2050 despite geopolitical, metabolic, and environmental threats

Brightest gamma-ray burst of all time came from the collapse of a massive star

A virus could help save billions of gallons of wastewater produced by fracking

Massive merger: Study reveals evidence for origin of supermassive black hole at galaxy's center

Investigating newly discovered hydrothermal vents at depths of 3,000 meters off Svalbard

More Women Underwent Surgical Sterilization After Fall of Roe v. Wade

Fall of Roe v. Wade Has Made Access to Ob/Gyns Tougher in Many States: Report

Stroke Rates Are Rising, Especially Among the Young

Almost All Counterfeit Oxycontin Pills Contain Fentanyl

Video gaming improves mental well-being, landmark study finds

Ketamine Use Is on the Rise in U.S.

U.S. Infant Deaths Rose After Fall of Roe v. Wade

Big Rise in Emergencies Involving Synthetic Weed Among Kids, Adults

Humira leads ICER’s latest list of ‘unsupported’ price hikes

Holographic 3D printing has the potential to revolutionize multiple industries

High Rates of Loneliness Seen Among Bisexual and Transgender People

Cancer mortality continues to drop despite rising incidence in women

Steady Rise in U.S. Cases of Tick-Borne Babesiosis Disease

Number of Americans With Type 2 Diabetes Jumped by 20% in a Decade

Rates of Anxiety, Depression Rising Among Americans, Especially the Young

U.S. Births Continue to Fall, Dropping by 17% Since 2007

The heat index -- how hot it really feels -- is rising faster than temperature

U.S. Life Expectancy Rose Overall, But Overdose Deaths Still Set Records

Stigma, Shame Hit Many Gay Men Affected by Mpox Outbreak

Gross-to-Net Bubble Update: 2022 Pricing Realities at 10 Top Drugmakers

In Mississippi, a Huge Jump in Cases of Babies Born With Syphilis

Bird Flu Is Spreading: What You Need To Know

NASA's Fermi finds new feature in brightest gamma-ray burst yet seen

Gross-to-Net Bubble Update: 2022 Pricing Realities at 10 Top Drugmakers (rerun)

Poll Finds Many Young Workers Feeling Stressed, Isolated

Diphtheria-Like Germ Can Be Passed Between People and Pets

Homeless Americans' Death Rate Rises on Hot Days

More Than Half of Heat Deaths Can Be Blamed on Global Warming: Study

Drug-Linked Infant Deaths Doubled in U.S. in 4 Years

U.S. Drowning Deaths Rising Again After Years of Decline

Early Deaths From Heart Disease Rising in Rural U.S.

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