The Strateos Blog: Drug Discovery

DECEMBER 13, 2021

We are excited to share that Strateos’ SVP of Strategy & Operations, Daniel Sipes, will be delivering a presentation entitled Accelerating Medicinal Chemistry Cycle Times Through Cloud-Accessible Smart Automated Labs at the upcoming 2022 Society for Laboratory Automation and Screening Conference & Exhibition between February 5-9th.

Biochemical Assays 52

Biochemical Assays Small Molecule Laboratories Science 52

Drug Target Review

JANUARY 5, 2024

Å resolution) 6 is now being targeted for small molecule inhibitor discovery and development, by exploiting emergent computational tools to identify potential candidate compounds in silico and then test these predicted inhibitors in in vitro biochemical assays. Journal of Biological Chemistry 298(8), 102167 (2022).

Small Molecule 59

Small Molecule Drugs Biochemical Assays Regulations 59

Practical Cheminformatics

AUGUST 3, 2023

In a 2022 review by Haddad of the CNS penetration of antibiotics, the percentage of Ceftriaxone in CSF relative to plasma varied between 0.5 Initially, I would recommend aqueous solubility, membrane permeability, in vitro metabolic stability, and biochemical assays.

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Drugs Biochemical Assays Metabolic Stability Screening Hits 93

Agency IQ

JUNE 26, 2023

Further, footnote 7 in the document explains: “Examples of such clinical laboratory tests are commonly used and well understood biochemical assays (e.g., One recent interesting case study on the issue: A December 2022 Advisory Committee meeting.

FDA 40

FDA Clinical Trials Laboratories Science 40

Agency IQ

APRIL 12, 2024

Assays are tests designed to assess various properties (like potency) of chemical or biological samples. Those who are taking the guidance in stride may have participated in a series of six town hall meetings conducted between September 2022 and August 2023.

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Production FDA Therapies Biochemical Assays 40