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We Need Better Benchmarks for Machine Learning in Drug Discovery

Practical Cheminformatics

The ability of a compound to enter the CNS can also be facilitated or hindered by certain disease states. In a 2022 review by Haddad of the CNS penetration of antibiotics, the percentage of Ceftriaxone in CSF relative to plasma varied between 0.5 Various experimental techniques have been applied to the measurement of CNS penetration.

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