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Obstacles and innovations of macrocyclic drug development

Drug Target Review

Cell , 185(19):35203532, 2022. Cyclic Peptide Design, Chapter 2: Strategies to Enhance Metabolic Stabilities. Considering the impact drug-like properties have on the chance of success. Drug Discovery Today , 18(13-14):659666, 2013. Bhardwaj G, OConnor J, Rettie S, et al. Hoang HN, Hill TA, Fairlie DP. Springer, 2019.