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Transforming high-throughput screening with mass spectrometry

Drug Discovery World

Trapped ion mobility spectrometry: Improving the specificity of MALDI-MS-based HTS . The ability of MALDI-enabled TOF and QTOF systems to discriminate between analytes and sample matrix background components based on their specificity is, like other MS techniques, dependent upon the mass resolution. References . Attene-Ramos and M.

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Measure Cell Metabolism with Microplate Readers | BMG LABTECH

BMG Labtech

DNA, proteins, polysaccharides, etc.). Cells require energy for this process. 2 Organisms are categorised based on their anabolism and according to the source used by cells to build-up molecules. An active metabolism is a sign of viable cells and can be hence exploited by viability assays (fig.12)