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TACACICLIB, AUR-102, AURIGENE

New Drug Approvals

As such, it has been proposed that inhibiting CDK7 would provide a potent means of inhibiting cell cycle progression, which may be especially relevant given that there is compelling evidence from gene knockout studies in mice for lack of an absolute requirement for CDK2, CDK4 and CDK6 for the cell cycle at least in most cell types (M alumbres et al.,

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Advanced 3D cell-based technologies

Drug Target Review

This major shift to the orthodox tradition of using animal experiments in drug testing dates back the Aristotle’s time and cemented 80 years ago with initial federal mandate of drug safety regulation of 1938. From 3D cell culture to organs-on-chips. Trends in Cell Biology. 2010;328(5986):1662-8. 2011;21(12):745-54.

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Codon Digest: Injected Gene Editors

Codon

Read Safety and pharmacokinetics of escalating doses of neutralising monoclonal antibody CAP256V2LS administered with and without VRC07-523LS in HIV-negative women in South Africa (CAPRISA 012B): a phase 1, dose-escalation, randomised controlled trial. An open-source FACS automation system for high-throughput cell biology.

DNA 52