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Sygnature Discovery completes acquisition of SB Drug Discovery to further strengthen its market-leading capabilities

Sygnature Discovery

Sygnature Discovery (“Sygnature”) is delighted to announce the acquisition of SB Drug Discovery, a world leading provider of ion channel and receptor drug discovery research delivering cell line generation and compound screening solutions in neuroscience and other therapeutic indications. SB is based in Glasgow and employs 55 people.

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Taking a new approach to tackle neurodegenerative diseases

Drug Discovery World

Using its proprietary compound screening platform, Oligomerix discovers and develops differentiated, oral, small molecule inhibitors of tau self-association that are easy to administer and cost-effective. . million in 2022 to 12.7 Volume 23 – Issue 4, Fall 2022. million by 2050.” . About the author .

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What to expect from drug discovery and development in 2023

Drug Discovery World

The Market After over two years of the Covid-19 pandemic, 2022 year was somewhat of a return to normal for both the world at large and the pharmaceutical industry. As such, 2022 saw a marked fall in ROI for global pharmaceutical companies and their research and development activities. However, that is not to say it was an easy year.

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AI use in repurposing drugs for Covid-19

Drug Discovery World

They cannot be easily scaled or broadly applied to other therapeutic programs or disease areas, and the data generated from any compound screens will be narrowly focused on the target hypothesis. DDW Volume 24 – Issue 1, Winter 2022/2023 The post AI use in repurposing drugs for Covid-19 appeared first on Drug Discovery World (DDW).

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Resources, services, and tools

Broad Institute

Resources, services, and tools By Maria Nemchuk July 26, 2022 Breadcrumb Home Resources, services, and tools Key scientific datasets and computational tools developed by our scientists and their collaborators. Learn more PRISM Rapid, high-throughput multiplexed compound screening in genomically characterized human cancer cell-line models.

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Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

Manual patch-clamping of single cells has become a mainstay of functional electrophysiology, often used to follow up after novel hit compounds are identified by non-functional fluorescence or ligand binding methods, which are considerably higher in their throughput. 2022) Nature Reviews Drug Discovery, 21: 915–931. Scannell et al.

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