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Taking a new approach to tackle neurodegenerative diseases

Drug Discovery World

William Erhardt , President, Head of Development & Operations of biotech Oligomerix, tells Lu Rahman about the company’s differentiated approach to developing disease-modifying therapeutics for neurodegenerative diseases. . million in 2022 to 12.7 In the US alone, AD prevalence is expected to increase from 6.5

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What to expect from drug discovery and development in 2023

Drug Discovery World

The Market After over two years of the Covid-19 pandemic, 2022 year was somewhat of a return to normal for both the world at large and the pharmaceutical industry. As such, 2022 saw a marked fall in ROI for global pharmaceutical companies and their research and development activities. However, that is not to say it was an easy year.

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AI use in repurposing drugs for Covid-19

Drug Discovery World

There was an urgent need for quick and adaptable drug discovery in the context of a complex and poorly understood disease. Our goal was to quickly identify existing therapeutics that could be repurposed for Covid-19 treatment by screening a library of approved and late-stage development drugs against a disease model in our platform.

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Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

Cardiovascular diseases are the leading cause of death globally. A more recent analysis has illustrated how both assay validity and reproducibility correlate across a population of simulated screening and disease models 2. 3 argued that the choice of screening and disease models often depends on tradition or availability.

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Resources, services, and tools

Broad Institute

Resources, services, and tools By Maria Nemchuk July 26, 2022 Breadcrumb Home Resources, services, and tools Key scientific datasets and computational tools developed by our scientists and their collaborators. Learn more PRISM Rapid, high-throughput multiplexed compound screening in genomically characterized human cancer cell-line models.