2022 FDA Approval Metabolic Stability Pharmaceuticals 
Metabolite Tales Blog
MAY 12, 2023
Now >20% of all commercialised medicines in the pharmaceutical industry contain a fluorine atom [2]. In 2021, almost one third of FDA approved drugs contained at least one fluorine. References [1] Metabolic and Pharmaceutical Aspects of Fluorinated Compounds. 2022), JBMR Plus, 6: e10557. Benjamin M.
Practical Cheminformatics
AUGUST 3, 2023
Most pharmaceutical compounds tend to have solubilities somewhere between 1 and 500 µM. In a 2022 review by Haddad of the CNS penetration of antibiotics, the percentage of Ceftriaxone in CSF relative to plasma varied between 0.5 Many have suggested that pharmaceutical companies should open more of their data to the community.
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