Drug Hunter

APRIL 23, 2023

log in: Username or E-mail Password Remember Me Forgot Password The post Drug Hunter Journal Club: March 2023 appeared first on Drug Hunter. BCCov “A covalent BTK ternary complex compatible with targeted protein degradation” Nat. Get ahead now by requesting a trial. already a member?

Targeted Protein Degradation 130

Targeted Protein Degradation Drugs Trials 130

Science Daily: Pharmacology News

SEPTEMBER 12, 2024

The study concluded that this movement of water was the cause of a mysterious, global seismic signal that lasted for nine days and puzzled seismologists in September 2023.

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Drug Discovery Today

SEPTEMBER 11, 2023

Professional excellence, positive environmental impact, process safety and societal benefit are among the key qualities being celebrated by the Institution of Chemical Engineers (IChemE) as it announces the finalists for its 2023 Global Awards.

Engineering 113

Engineering 113

Science Daily: Pharmacology News

MAY 14, 2024

Researchers have found that 2023 was the hottest summer in the Northern Hemisphere in the past two thousand years, almost four degrees warmer than the coldest summer during the same period.

Research 122

Research 122

keypoint

DECEMBER 4, 2023

Checkout the latest news & views from Keystone Symposia in our December 2023 Keypoint Newsletter, featuring Health Equity highlights, new 2-day meeting format, upcoming AI in Biomedicine virtual meeting & more!

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KIF1A

SEPTEMBER 2, 2023

2023 KAND Family & Scientific Engagement Conference Wrap-up A happy Labor Day weekend to our readers in the US! It’s hard to believe that a month ago KAND families were arriving in New York City from all around the world to participate in the KOALA trial-readiness study and attend our 2023 conference. Gallagher et al.

Disease 111

Disease Science Research Trials 111

KIF1A

NOVEMBER 4, 2023

2023, Cell Reports. Read the Press Release The post #ScienceSaturday: November 4, 2023 appeared first on KIF1A. elegans worms grow, certain neurons eliminate synapses near their cell body, and grow synapses further from their cell body. This process relies on moving material from old synapses to new ones. From Cuentas-Condori et al.

Treatment 111

Treatment Disease Research Science 111

KIF1A

OCTOBER 7, 2023

2023 Studies like these that reassess umbrella disorders for genetic contributions are a two-fold advantage; we can use overlap between disease subtypes to search for common therapeutic approaches, and use distinctions between subtypes to suss out the leads most likely to apply to our smaller community. Lischka et al.

Disease 111

Disease Treatment Regulations Therapies 111

Drug Hunter

JUNE 14, 2023

The post Molecules of the Month – May 2023 appeared first on Drug Hunter.

Drugs 130

Drugs 130

KIF1A

SEPTEMBER 9, 2023

2023 There were also discrepancies between Nup153 and KIF1A knockdowns that are worth further investigation: For example, Nup153 knockdown, but not KIF1A knockdown, caused RGPs to stall during cell division, indicating that Nup153 could be regulating other proteins at the nucleus. Falnikar et al. What’s a pre-print?

RNA 105

RNA Treatment Research Disease 105

Elrig

DECEMBER 19, 2023

The post ELRIG Drug Discovery 2023 meeting highlights first appeared on ELRIG. Relive Drug Discovery 23 with SelectScience’s hub that features exclusive content from the event.

Drugs 98

Drugs Science 98

KIF1A

SEPTEMBER 23, 2023

Check out Dr. Jayne Aiken’s talk from our 2023 Scientific & Family Engagement Conference. The post #ScienceSaturday: September 23, 2023 appeared first on KIF1A. Check out this #ScienceSaturday post to learn more. Read the Article Want to learn more about KIF1A work at the Holzbaur Lab?

Regulations 111

Regulations Disease Science Production 111

keypoint

SEPTEMBER 6, 2023

In June we concluded our 2023 season, which ran from August 2022 to June 2023, aligning with the academic year. It was a busy season, consisting of 60 meetings altogether, including 13 that had been rescheduled due to the pandemic.

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LifeSciVC

NOVEMBER 17, 2023

2023 couldn’t end fast enough for most of us in biopharma; its been a tough year in the capital markets, and the industry is facing it’s fair share of headwinds. This month we held our 2023 Annual General Meeting for our fund’s investors and our Atlas Venture Retreat with industry executives.

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Science Marketing Production Disease 97

Drugs.com

JUNE 21, 2024

FRIDAY, June 21, 2024 -- For the fourth year in a row, rates of gun injuries stayed above levels seen before the pandemic, a new government report shows.Race played a key role in who saw those higher rates of gun violence in 2023, the researchers.

Government 98

Government Research 98

keypoint

SEPTEMBER 6, 2023

The September 2023 issue of the Keypoint Newsletter features the latest news and views from Keystone Symposia, including our new Climate Initiatives, the new KS Career Connect Job Posting Site, Launch of the Post-doc arm of the Fellows Program, Recap of the 50th Anniversary Gala Celebration, and upcoming program highlights like Long-COVID, Next-Generation (..)

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Science Daily: Pharmacology News

JANUARY 14, 2024

Earth's average surface temperature in 2023 was the warmest on record, according to an analysis by NASA. Global temperatures last year were around 2.1 degrees Fahrenheit (1.2 degrees Celsius) above the average for NASA's baseline period (1951-1980), scientists from NASA's Goddard Institute for Space Studies (GISS) in New York reported.

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KIF1A

JULY 8, 2023

2023 The researchers first established a baseline by measuring how often cargo at intersections move straight ahead, turn toward the synapse, or pause. Read the Article The post #ScienceSaturday: July 8, 2023 appeared first on KIF1A. At the bottom we see a PLM neuron, where KIF1A carries cargo down the major neurite.

Therapies 98

Therapies Regulations FDA Treatment 98

Fierce BioTech

SEPTEMBER 27, 2023

Genesis 2023 Join industry leaders at Genesis 2023! Learn more: genesisconference.com rwatanabe Wed, 09/27/2023 - 09:26 Join industry leaders at Genesis 2023! Connect with key Life Science opinion leaders and stakeholders to debate key trends, instigate deals, and inform visions of the future.

Science 52

Science 52

Science Daily: Pharmacology News

DECEMBER 4, 2023

Global carbon emissions from fossil fuels have risen again in 2023 -- reaching record levels, according to new research.

Research 122

Research 122

KIF1A

JUNE 10, 2023

From Barmaver and Wagner (pre-print, 2023) In the figure above we see KIF1A, SFXN-1.2, The FDA will issue two separate decisions, one for each disease application: Sickle cell disease in December of 2023, and beta thalassemia in March of 2024. Read the Article The post #ScienceSaturday: June 10, 2023 appeared first on KIF1A.

Clinical Trials 98

Clinical Trials FDA Disease Regulations 98

Broad Institute

DECEMBER 13, 2023

2023 Cohort By Rose Circeo December 13, 2023 Breadcrumb Home Broad Biomedical Post-baccalaureate Scholars Program 2023 Cohort John Adeleye Townson University Healthcare Administration, B.S. Sheng Group, Stanley Center Rebecca Barrick Brandeis University Biochemistry, B.S.

Molecular Biology 52

Molecular Biology Cell Biology Science Engineering 52

KIF1A

SEPTEMBER 30, 2023

Read the Article The post #ScienceSaturday: September 30, 2023 appeared first on KIF1A. In addition to benefiting awarded sponsors, this pilot program will help create best practices of communication with the FDA during rare disease therapeutic development.

Disease 111

Disease FDA Clinical Trials Therapies 111

Science Daily: Pharmacology News

JANUARY 11, 2024

Record heat across the world profoundly impacted the global water cycle in 2023, contributing to severe storms, floods, megadroughts and bushfires, new research shows.

Research 111

Research 111

KIF1A

JULY 29, 2023

KIF1A in New York: The 2023 KAND Family & Scientific Engagement Conference We won’t be posting next Saturday, but not for a lack of science! Read the Article The post #ScienceSaturday: July 29, 2023 appeared first on KIF1A. KIF1A.ORG is actively working to build advocacy strategies for just this purpose, so stay tuned!

RNA 98

RNA Clinical Trials Disease Science 98

KIF1A

JULY 22, 2023

2023 Scientific findings need to be validated, replicated, and applied to new systems; this is the reason KIF1A.ORG has invested in our Treatment Accelerator Program. Read the Article The post #ScienceSaturday: July 22, 2023 appeared first on KIF1A. ” Chai et al.

Small Molecule 98

Small Molecule FDA Disease Treatment 98

KIF1A

JUNE 24, 2023

J Cell Biol 7 August 2023; 222 (8): e202208121. Read the Article The post #ScienceSaturday: June 24, 2023 appeared first on KIF1A. In the presence of zinc these cargo slowed and stopped more often, and these effects could be reversed by removing the zinc. Minckley et al. How does zinc inhibit cargo transport?

Regulations 98

Regulations Research Disease Science 98

KIF1A

JULY 15, 2023

2023, Neuron. Read the Article The post #ScienceSaturday: July 15, 2023 appeared first on KIF1A. By using machine learning, researchers can identify subtle movements that may be associated with epilepsy. By identifying short and subtle changes in movements, we may be able to characterize epileptic events with more precision.

Disease 98

Disease Treatment Research Therapies 98

KIF1A

SEPTEMBER 16, 2023

Read the Article The post #ScienceSaturday: September 16, 2023 appeared first on KIF1A. This is also important when newborns present as having a “common” disorder that may have a rare genetic component, like KIF1A in genetic cerebral palsy.

Regulations 105

Regulations RNA Disease Research 105

KIF1A

MAY 31, 2024

Reflecting on a Remarkable Year: KIF1A.ORG’s 2023 Annual Report Dear KAND Community, Let’s take a moment to reflect on the incredible journey we’ve shared in 2023. In February of 2023, Boston Children’s Hospital named Dr. Chung Chief of the Department of Pediatrics.

Treatment 52

Treatment Small Molecule International Research 52

Drugs.com

APRIL 25, 2024

births may be over, with 2023 numbers showing a decline in births.According to provisional data from the U.S. THURSDAY, April 25, 2024 -- The short post-pandemic uptick in U.S. Centers for Disease Control and Prevention, just under 3.6

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Disease 98

addgene Blog

JANUARY 23, 2024

I am proud of what we accomplished in 2023 and thrilled to be sharing our plans for 2024. With renewed energy and optimism that comes at the start of every new year, it is a wonderful opportunity to once again reflect on our achievements in the last year and share the exciting things to come in the new year.

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KIF1A

OCTOBER 14, 2023

You can find the entire colloquium recording below: See the Colloquium Agenda The post #ScienceSaturday: October 14, 2023 appeared first on KIF1A.

Disease 105

Disease Treatment Research Production 105

SCIENMAG: Medicine & Health

AUGUST 16, 2023

August 16, 2023–Distinguished global health leader Ibrahim Abubakar is the recipient of the 2023 Roux Prize for his dedication to improve health outcomes over the last three decades. SEATTLE, Wash.

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KIF1A

OCTOBER 28, 2023

See the Tournament Page The post #ScienceSaturday: October 28, 2023 appeared first on KIF1A. Proceeds will go to the KIF1A Rare Pediatric Disease Program at Boston Children’s Hospital , led by Dr. Wendy Chung.

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Disease Treatment Research Hospitals 105

KIF1A

OCTOBER 21, 2023

Read the Article The post #ScienceSaturday: October 21, 2023 appeared first on KIF1A. We know that our community benefits from a slew of doctors who have gone above and beyond to understand and help manage KAND cases; we also know that many times KAND families come to doctors as KAND experts.

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Regulations Doctors Disease Packaging 105

KIF1A

MAY 27, 2023

I am excited to attend the upcoming 2023 KAND Family and Scientific Engagement Conference in person, that will enable our community to reflect upon the progress and to design the next steps to address the KAND therapeutic development challenge collaboratively.

Science 94

Science Small Molecule Disease Research 94