Remove 2023 Remove Assay Development Remove DNA Remove Vaccine
article thumbnail

Early phase support for plasmid DNA supply to secure future manufacturing

Drug Discovery World

This paid-for advertorial by Catalent appeared in DDW Volume 24 – Issue 1, Winter 2022/2023 One significant challenge in the manufacturing of cell and gene therapies is the production of high-quality plasmid DNA (pDNA). Figure 1: The integrated development pathway for cell and gene therapies.

DNA 130
article thumbnail

The path to improved safety of gene-based products

Drug Discovery World

Gene-based therapeutics and vaccines hold immense potential for more efficient and personalised treatment and prevention of complex diseases. In these cases, injection of the viral vector vaccines induced the production of antibodies recognising platelet factor 4 (PF4) found on patients’ platelets 1.

article thumbnail

Advances in cell line development

Drug Discovery World

According to Grand View Research, the global cell line development market was valued at $4.81 billion in 2022, a figure that is expected to grow at a compound annual growth rate (CAGR) of 9.81% from 2023 to 2030 1. There are a lot of considerations to take when choosing a cell line. Bacterial cell lines such as E.

Vaccine 147