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Bile acids and the microbiome: revolutionising disease approaches

Drug Target Review

Bile acids are crucial signalling molecules that aid the regulation of the immune system and have essential metabolic functions, like controlling lipid and glucose metabolism. 2023 February 5 [2024 March 11]; 15(1). Biochemical Pharmacology. Bile acids as modulators of gut microbiota composition and function.

Disease 111
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Targeting the immunotherapy potential of cytokines IL-12 and IL-18 with new advancements in protein engineering

Drug Target Review

This suppressive mechanism involves a negative regulator – a protein called IL-18BP or IL-18 binding protein, that works as a “decoy receptor” by binding to IL-18 and preventing it from binding to its functional receptor. National Library of Medicine; [cited 2023 Jun 6]. References: M; LWR. Available from: [link]