Drug Target Review

AUGUST 10, 2023

A breakthrough study conducted by researchers at the Keck School of Medicine of USC has shown a remarkable finding: during moments of stress, cancer cells undergo a transformative process. A crucial protein within these cells migrates to the nucleus, effectively reprogramming them to exhibit increased mobility and invasiveness.

Cell Biology 52

Cell Biology Small Molecule Regulations Engineering 52

Drug Target Review

NOVEMBER 1, 2023

2 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. 1-5 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. He is a researcher at University of Oldenburg, Germany. 2017;2017:1–15.

Clinical Trials 134

Clinical Trials Small Molecule Trials Pharmacokinetics 134

Drug Discovery World

NOVEMBER 8, 2023

On Day 1, Tuesday 14 November 2023, the tracks include: Display of biologics, antibody-based cancer therapies, safety and efficacy of bispecific antibodies, modulating the tumour microenvironment, optimisation and developability, and cell line and systems engineering. from engineered peptide and antibody libraries’.

Engineering 162

Engineering Protein Expression Therapies Science 162

Precision for Medicine

APRIL 7, 2023

This provides value to researchers executing clinical trials, particularly those developing novel therapeutics and vaccines, where sample processing requires geographical proximity to the trial site and samples need to be processed within hours of collecting them from patients.

Laboratories 52

Laboratories Clinical Research Clinical Trials Cell Biology 52

Drug Discovery World

APRIL 16, 2023

DDW’s Megan Thomas rounds up highlights from Sunday 16 April at AACR 2023, from promising trial results for a personalised mRNA-based cancer vaccine to winners of lifetime achievement awards. Phyllis Pettit Nassi, MSW, is the Associate Director, Research and Science, Special Populations at the Huntsman Cancer Institute.

Clinical Trials 130

Clinical Trials Vaccine Trials Science 130

The Pharma Data

OCTOBER 27, 2021

million expansion will bring high quality seeds to worldwide markets faster, providing solutions for growers and meeting consumer demands / The seven-hectare global Product Design Center in San Nicolás includes state-of-the-art lab space for cell biology research and greenhouses for seed production.

Cell Biology 40

Cell Biology Production Laboratories Marketing 40

Drug Target Review

OCTOBER 31, 2023

When I was studying cell biology, looking at how cells divide, I couldn’t fathom how math could possibly fit into that. My undergraduate studies focused on biochemistry and cell biology, so very much STEM-based, but my professors and mentors noticed my penchant for critical thinking which led me to consider law.

Cell Biology 107

Cell Biology Pharmaceuticals Science International 107

Drug Discovery World

NOVEMBER 13, 2023

On Day 3, Thursday 16 November 2023, the tracks include: the second part of machine learning for protein engineering, antibodies against membrane protein targets, engineering bispecific antibodies, next-generation immunotherapies, protein stability and formulation, and protein process development.

Engineering 147

Engineering Science Bioinformatics Vaccine 147

KIF1A

MAY 24, 2023

It’s an investment in the long-term success of rare disease research, even if it doesn’t provide an immediate clinical on-ramp. Rebecca Shi of Stanford University, who worked to create a research laboratory course for undergraduates in the Stanford Biology department for the Spring 2023 semester.

Disease 98

Disease Laboratories Research Science 98

Drug Discovery World

OCTOBER 12, 2023

ELRIG’s Drug Discovery 2023 will be taking place at ACC Liverpool, UK from 18-19 October 2023, focusing on the importance of a diverse life science ecosystem. Such approaches may include cellular technologies for drug discovery, such as a 3D screening model, a topic which will be discussed at Drug Discovery 2023.

Drugs 147

Drugs Science Cell Biology Therapies 147

Broad Institute

NOVEMBER 2, 2023

Q&A: How generative AI could help accelerate biomedical research By Corie Lok November 2, 2023 Breadcrumb Home Q&A: How generative AI could help accelerate biomedical research A machine learning and AI expert discusses how generative AI could be used not just to write emails and computer code, but also to analyze biological data.

Research 125

Research Engineering Science Cell Biology 125

Broad Institute

OCTOBER 11, 2023

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. Omar Avila Monge puts samples — immune cells isolated from tumors treated with the PTPN2 inhibitor — into a centrifuge.

Research 137

Research Immune Response Clinical Trials Cell Biology 137

Drug Discovery World

JANUARY 19, 2023

This paid-for advertorial by Sphere Fluidics appeared in the SLAS 2023 Supplement, Volume 24 – Issue 1, Winter 2022/2023 Modern drug development has expanded from chemist-made substances to biologics and cell-based therapies. Now, two and a half decades later, a new approach inspired by nature is making the news: cell therapy.

Treatment 130

Treatment Cell Biology Therapies Drugs 130

Drug Target Review

NOVEMBER 17, 2023

The relative ease and lower cost of manufacture (potentially a few thousand dollars) compared to autologous T cell therapies (hundreds of thousands of dollars), coupled with their functional attributes and safety profile, make NK cells an attractive therapeutic option for cancer patients, but surprisingly this is not universally recognised.

Therapies 117

Therapies Cell Biology Clinical Trials Trials 117

Broad Institute

FEBRUARY 29, 2024

Senior Research Scientist Michal Lipinski is a senior research scientist at the Spatial Technology Platform of the Broad Institute of MIT and Harvard, where he works under the supervision of Sami Farhi. Nat Methods. 2021;18(11):1352-1362. doi:10.1038/s41592-021-01264-7 Michal Lipinski, Ph.D. Lipinski earned his Ph.D.

Cell Biology 52

Cell Biology Disease Science Research 52

Drug Target Review

JUNE 29, 2023

Could you share an example of a specific project or some research that you have worked on and the impact it has had in your field? How has your research in STEM contributed to advancements or improvements in your field, and what potential future applications or implications do you foresee based on your work?

Therapies 114

Therapies Science Production Cell Biology 114

Drug Target Review

APRIL 12, 2024

Controlling the amount of RNP entering each cell is challenging, leading to uncertainty about the ratio of RNP that reaches any specific cell. Importantly for the researcher, there is no assurance that the RNP, once inside the cells, will reliably enter their nuclei. References [1] [link]. [1] 1] Rosen, H.

Cell Biology 105

Cell Biology FDA Approval FDA Research 105

Drug Target Review

APRIL 12, 2024

Controlling the amount of RNP entering each cell is challenging, leading to uncertainty about the ratio of RNP that reaches any specific cell. Importantly for the researcher, there is no assurance that the RNP, once inside the cells, will reliably enter their nuclei. References 1 [link]. 2 Rosen, H.

Cell Biology 98

Cell Biology FDA Approval FDA Research 98

Elrig

APRIL 29, 2024

With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. Miguel Gancedo Rodrigo Miguel Gancedo Rodrigo Research Investigator, Isomorphic Labs My name is Miguel, and I’m from Murcia, Spain.

Bioinformatics 59

Bioinformatics Molecular Biology Drugs Cell Based Assays 59

The Pharma Data

MARCH 11, 2021

Second, the biorevolution is driving innovation in all of Bayer’s divisions – with major progress in cell biology, gene editing and data science. through 2023. In light of increased R&D investment, the Pharmaceuticals Division is expected to achieve an EBITDA margin before special items of 32 to 34 percent through 2023.

Science 52

Science Pharmaceuticals Licensing Licensing 52

Codon

APRIL 9, 2023

This is Codon Digest, my weekly roundup of research, news, and industry highlights about the future of biology. Nucleic Acids Research. Nature Cell Biology. Nucleic Acids Research. Read Truncated CD19 as a selection marker for the isolation of stem cell derived β-cells. Nature Methods.

Therapies 52

Therapies RNA Engineering Vaccine 52

DrugBank

JUNE 27, 2023

As researchers increased their ability to gather large amounts of genetic data, they gained the ability to study the genome as a whole, giving rise to the field of genomics. However, it does highlight the challenge in sufficiently defining a “condition,” both for research and clinical practice.  Hallgrimsson, B.,

Disease 89

Disease Treatment Drugs DNA 89

Broad Institute

JULY 28, 2023

Neurobiology & Organismal Biology By Maria Nemchuk July 28, 2023 Breadcrumb Home Neurobiology & Organismal Biology Takao Hensch, Harvard/Boston Children’s Hospital Takao Hensch Takao Hensch Takao Hensch , Ph.D. Conte Center for Basic Mental Health Research at Harvard. He currently directs an NIMH Silvio O.

Medical Schools 52

Medical Schools Hospitals Regulations Research 52

Codon

AUGUST 10, 2023

Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). . & Weiss R.

DNA 98

DNA Cell Biology Molecular Biology Engineering 98

Codon

AUGUST 10, 2023

Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Last edit: 13 September 2023 Progress in biology is arguably moving faster today than at any point in the course of human history. Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. & Weiss R.

DNA 52

DNA Cell Biology Engineering Molecular Biology 52

Codon

APRIL 16, 2023

Codon Digest is my weekly roundup of research, news, and industry highlights about engineered biology. AI + Bio *Emergent autonomous scientific research capabilities of large language models. Nature Cell Biology. Read *Open-endedness in synthetic biology: a route to continual innovation for biological design.

Engineering 52

Engineering DNA RNA Science 52