Drug Discovery World

OCTOBER 20, 2023

In July 2023, Phesi released data showing that, in the first half of 2023, 31% of trials at Phase II had been cancelled. The clinical trials industry is facing a chronic challenge,” commented CEO and founder of Phesi, Dr Gen Li. Protocol amendments slow down clinical development and are extremely costly.

Clinical Trials 162

Clinical Trials Trials Marketing Drugs 162

Cytel

OCTOBER 27, 2023

Since its launch in 2021, Project Optimus has been reforming the dose optimization and dose selection paradigm in oncology drug development. To address this challenge, the FDA Oncology Center of Excellence initiated Project Optimus. With consensus of multiple stakeholders on “why” the change is needed, the speakers focused on “how.”

Clinical Trials 64

Clinical Trials Trials Clinical Pharmacology Clinical Development 64

Drug Discovery World

JUNE 1, 2023

A market research report published in late June 2018 by HTF market Intelligence Consulting suggested that the ADC market in China would grow exponentially by 2023 4. This appears to be supported by the number of Chinese collaborations, approvals and expansions in 2023 alone.

Marketing 245

Marketing FDA Approval Licensing Licensing 245

Broad Institute

NOVEMBER 2, 2023

Bayer and Broad Institute extend cancer therapy research collaboration By Corie Lok November 2, 2023 Breadcrumb Home Bayer and Broad Institute extend cancer therapy research collaboration Long-standing industry-academia collaboration has already resulted in three clinical oncology candidates.

Therapies 106

Therapies Research Small Molecule Clinical Trials 106

Drug Discovery World

MAY 6, 2024

Even before this, however, Amsterdam was established as an important centre for drug development. In a boost to cancer research for both regions, in November 2023, Cancer Research UK and the KWF Dutch Cancer Society (KWF) announced a multi-project strategic partnership. The CDD will sponsor and manage KWF-supported trials.

Drugs 147

Drugs Molecular Biology Science Clinical Trials 147

Drug Discovery World

MARCH 7, 2023

Powers taught for more than six years at the National Institutes of Health, on medical product development and commercialisation, and at Georgetown Law School as an adjunct professor. Dr Janette Thomas, CEO, Five Alarm Bio Five Alarm Bio is an anti-ageing therapeutics company, which completed a seed investment round in early 2023.

International 246

International Science Pharmaceuticals DNA 246

Drug Discovery World

APRIL 13, 2023

With RWD, fewer patients require direct enrolment in randomised clinical trials. This enables broader patient inclusion and saves a significant amount of time throughout the clinical development process, while facilitating improved access to new drugs in new markets for the global patient population.

Clinical Trials 130

Clinical Trials Trials FDA Laboratories 130

Drug Discovery World

NOVEMBER 9, 2023

At CDR-Life, we believe that our antibody-based, modular, T-cell engager platform, which is directed against MHC-peptide targets, has excellent drug properties and is potentially superior to the soluble TCR-based T-cell engagers that are currently in clinical development.

Engineering 162

Engineering Clinical Trials Licensing Licensing 162

Drug Target Review

FEBRUARY 1, 2024

But commitment to neuroscience drug development is critically important given the significant unmet medical needs and the ways in which patients, caregivers, and families suffer. In other cases, well-established biomarker profiles enable patient enrichment strategies in early-stage clinical development.

Therapies 104

Therapies Drug Development Disease Clinical Development 104

Conversations in Drug Development Trends

FEBRUARY 22, 2023

What will have the greatest impact on rare disease patients in 2023? Katie Nichols, senior project manager at Worldwide Clinical Trials, has been dedicated to rare disease research for seven years, seeing the impact firsthand that the progression of rare disease research has on rare disease communities. So, I decided to pivot.

Disease 52

Disease Clinical Trials Trials Treatment 52

Drug Discovery World

FEBRUARY 12, 2024

Dr Pandora Pound , Fellow Oxford Centre for Animal Ethics explores the hinderances of animal testing in pharma and why new technologies such AI, genomics and synthetic biology c an further drug development. Published online September 27, 2023. Troubador Publishing; 2023. Clinical Development Success Rates 2006-2015.;

Animal Testing 147

Animal Testing Disease Trials Research 147

Vial

MARCH 1, 2024

Introduction Contract research organizations (CROs) are essential in pharmaceutical research and development (R&D). By geographical region, the global CRO services market in 2023 was dominated by North America. billion in 2023 attributable to its laboratory products and biopharma services segment (53.8% of total revenue).

Clinical Trials 52

Clinical Trials Clinical Research Laboratories Trials 52

PPD

NOVEMBER 30, 2023

As we approach the end of 2023, it’s time to reflect on the past 12 months and how advances in drug development shaped the pharma and biotech industries. These shifts are a prelude to further change and progress in the clinical trial landscape in 2024. Five Predictions for the Drug Development Industry in 2024 1.

Clinical Trials 98

Clinical Trials Trials Clinical Research Drug Development 98

Conversations in Drug Development Trends

JANUARY 24, 2024

However, they lack awareness of specific clinical trials that may be relevant to their patients, and they don’t always feel they have the knowledge to explain certain aspects of clinical trials confidently to patients and their family members. Enrolling adequate populations will be required to advance these programs.

Trials 75

Trials Disease Clinical Trials Clinical Research 75

Vial

APRIL 10, 2024

The increasing costs associated with in-house drug development have prompted biotech and pharmaceutical companies to increasingly outsource to contract research organization s (CROs) for assistance. The company reported a revenue of $11,116 million for the first nine months of 2023, marking a 4.2%

Clinical Trials 52

Clinical Trials Trials Compliance Clinical Research 52

Labcorp Drug Development

FEBRUARY 3, 2023

Welcome to the February 2023 Labcorp Drug Development Decentralized Clinical Trial (DCT) blog. With Rare Disease Day coming soon on February 28, we are going to focus on how patients, sites and investigators can benefit by improving the design and execution of rare disease trials. What is Rare Disease Day?

Trials 52

Trials Disease Clinical Trials Drug Development 52

Drug Discovery World

OCTOBER 16, 2023

From the Beatson Institute for Cancer Research in Glasgow, to Edinburgh Drug Discovery in the University of Edinburgh’s Institute for Genetics and Cancer (IGC). At ELRIG’s Scottish Research and Drug Development Forum meeting, DDW’s Diana Spencer provided a snapshot of drug discovery in Scotland.

Drugs 189

Drugs Science Therapies Targeted Protein Degradation 189

Vial

FEBRUARY 29, 2024

Contract research organizations (CROs) are an integral partner of the drug development process, as they play a pivotal role supporting clinical trial conduct for pharmaceutical, biotechnology, and medical device sponsor companies. between 2023 and 2032. By 2032, this value is expected to reach US$108 billion.

Clinical Trials 52

Clinical Trials Trials Clinical Research Marketing 52

PPD

NOVEMBER 14, 2023

In this complex environment, functional service partnership (FSP) models have become a solution of choice for pharmaceutical and biotech companies navigating the challenges of clinical development. This comes as the demand for qualified clinical research associates (CRAs) is expected to increase by more than 36% in the next decade.

Clinical Research 52

Clinical Research Clinical Development International Engineering 52

PPD

NOVEMBER 21, 2023

The drug development industry is constantly adapting and evolving to bring novel therapeutics to market to improve the lives of patients across the globe. While the drug development industry experienced setbacks during the COVID-19 pandemic, the field  is again gaining momentum reminiscent of its pre-pandemic pace.

Clinical Development 52

Clinical Development Clinical Trials Trials Clinical Research 52

LifeSciVC

JANUARY 16, 2024

By Aimee Raleigh, Principal at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Just in time for new years’ reflections and resolutions, this year’s JPM felt like a refreshing burst of enthusiasm for a sector that has seen its challenges in 2022 and 2023 but also some green shoots.

Small Molecule 139

Small Molecule Trials Therapies Disease 139

Alta Sciences

OCTOBER 30, 2023

Top 10 Life Science Resources pmjackson Mon, 10/30/2023 - 16:16 There’s a lot of life science content out there, which is why we’ve curated a selection of our expert insights, tips, case studies, and scientific and regulatory information for you. Catch up on what you may have missed below! Watch the video. Listen here. Read or listen now.

Science 52

Science Clinical Trials Pharmacokinetics Pharmacy 52

LifeSciVC

OCTOBER 18, 2023

By Bob Clarke, CEO of Kinaset Therapeutics, as part of the From The Trenches feature of LifeSciVC As we enter the final leg of 2023, navigating the investment market in biotech continues to be fraught with twists and turns. So, what are investors looking for? I mean it’s easy, right? Where are investments going in the current market?

Clinical Development 63

Clinical Development Marketing Clinical Trials Production 63

PPD

JUNE 22, 2023

Sponsors and clinical research organizations (CROs) alike are facing competitive recruiting from limited talent pools. These challenges were echoed in a 2022 industry survey conducted by the PPD clinical research business of Thermo Fisher Scientific. We are committed to operational excellence across drug development.

Clinical Research 52

Clinical Research Clinical Trials Trials Drug Development 52

The Pharma Data

MARCH 28, 2022

Dupixent peak sales ambition raised to more than €13 billion Chronic obstructive pulmonary disease 2023 pivotal readouts provide potential for additional Dupixent sales ambition upgrade 13 potential new medicines currently in the clinic to treat chronic inflammatory diseases, with 17 readouts expected by the end of 2024.

Small Molecule 52

Small Molecule Clinical Development Disease Science 52

Drug Discovery World

JANUARY 23, 2023

Dr Julie Warner is Vice President of Regulatory Affairs at global drug development consultancy, Boyds.

Clinical Trials 130

Clinical Trials FDA Drug Development Compliance 130

Drug Discovery World

MARCH 29, 2023

On January 31 2023, an internally circulated version of the European Commission’s overhaul of the EU’s pharma legislation was leaked, and published by Politico 1.

Clinical Trials 130

Clinical Trials Biosimilars Pharma Companies Production 130

FDA Law Blog: Drug Discovery

JANUARY 4, 2023

The purpose of these town halls are to discuss topics related to OTAT-regulated products, engage with product development stakeholders, and to provide information to help stakeholders to help advance drug development. Other Questions.

Therapies 59

Therapies Engineering Production FDA 59

PPD

OCTOBER 31, 2023

Our 2023 industry trends report found that an increasing number of sponsors have begun to gravitate toward the FSP model, with respondents now saying FSP engagements represent 26% of their clinical work on average. Moreover, FSP models allow drug developers to outsource individual functional services to gain efficiency and flexibility.

International 52

International Clinical Research Clinical Development Research 52

Alta Sciences

APRIL 17, 2024

Five Promising Treatment Areas in Early-Phase Drug Development in 2024 aasimakopoulos Wed, 04/17/2024 - 15:52 Early-phase drug development is an ever-changing landscape, as emerging science leads to new promising areas of research for the treatment of human health issues. Asia, and Europe.

Drug Development 52

Drug Development Treatment FDA Approval Therapies 52

Agency IQ

JULY 21, 2023

The paper recommends a risk-based approach that weighs patient safety and integrity of development data. BY KIRSTEN MESSMER, PHD, RAC JUL 18, 2023 11:07 PM CDT Regulatory background In April 2021, the E.U. An earlier report highlighted three key areas for international regulatory consideration when employing AI in drug development.

Science 40

Science Clinical Trials Regulations Trials 40

Vial

MARCH 27, 2024

Increasing Demand for Contract Research Organization (CRO) Support CROs are pivotal to the successful execution of clinical trials, offering a tailored resource of expertise, services, and logistical support that can significantly streamline the process for sponsors. from 2024 to 2030.

Clinical Trials 52

Clinical Trials Trials International Compliance 52

Agency IQ

FEBRUARY 12, 2024

Furthermore, the Consortium would also work to develop standardized approaches to nonclinical testing as well as a set of standardized analytical methods, which could be used to assess product quality and manufacturing processes and controls.

FDA 40

FDA Therapies Clinical Trials Virus 40

The Premier Consulting Blog

JUNE 18, 2023

This has opened new opportunities in pharmaceutical drug development, such as the ability to evaluate large complex databases and to integrate information in useful ways. One exciting application of these technologies is the use of in silico trials in the development of novel therapies for rare diseases.

Drug Development 52

Drug Development Disease Clinical Trials Drugs 52

FDA Law Blog: Drug Discovery

NOVEMBER 2, 2023

Lewis, Senior Regulatory Device & Biologics Expert — On October 20, 2023, FDA announced the availability of the final guidance authored by CBER titled “Voluntary Consensus Standards Recognition Program for Regenerative Medicine Therapies.” Tobolowsky & Richard A. It finalized a draft guidance published in 2022.

Therapies 59

Therapies FDA Production Regulations 59

Alta Sciences

JUNE 9, 2023

Accelerating Global Drug Development Timelines With Ethnobridging rmaloney Mon, 06/12/2023 - 16:07 HTML Safe Strategy to Save Time and Money Avoid repeating Phase I studies for drugs intended for the Asian market. Speak with an expert today to discuss your next clinical program. Watch the webinar.

Drug Development 40

Drug Development Clinical Trials Biosimilars Pharmacokinetics 40

Conversations in Drug Development Trends

DECEMBER 5, 2023

Vendors that seamlessly integrate with CROs, delivering services in a timely manner, regardless of which phase the clinical trial is in, can significantly help maintain drug development timelines.

Clinical Trials 52

Clinical Trials Trials Clinical Development Pharmaceuticals 52