The Open Targets Blog

SEPTEMBER 21, 2023

David Hulcoop, previously Strategy and Operations Director for the consortium, starts as Executive Director of Open Targets in October 2023. This involves scaling up the process of making a few grams of the compound in the lab to hundreds of tonnes in a factory, in an environmentally-friendly, cost-effective way.

Organic Chemistry 83

Organic Chemistry Process Chemistry Small Molecule Science 83

Metabolite Tales Blog

JULY 5, 2023

However, in the quest to tackle challenging disease targets with difficult drug binding sites, there is revived interest in developing this compound type to offer unique solutions. Current macrocycles in clinical use generally focus on treatment of infectious diseases, cancer and auto-immune disorders. Drug Hunter article, June 2023.

Metabolic Stability 52

Metabolic Stability Drugs FDA Approval Treatment 52

Metabolite Tales Blog

JULY 5, 2023

However, in the quest to tackle challenging disease targets with difficult drug binding sites, there is revived interest in developing this compound type to offer unique solutions. Current macrocycles in clinical use generally focus on treatment of infectious diseases, cancer and auto-immune disorders. Drug Hunter article, June 2023.

Metabolic Stability 52

Metabolic Stability Drugs FDA Approval Treatment 52