Drug Discovery World

OCTOBER 11, 2023

Until recently, many large pharmaceutical companies had stopped antibiotic research entirely as the returns on investment were too low and regulatory requirements too stringent 5. Additionally, drugs like quinolones and rifampin disrupt the synthesis of nucleic acids, which are essential for bacterial DNA replication. Ventola CL.

Protein Production 147

Protein Production Pharmaceutical Companies Production DNA 147

Codon

FEBRUARY 13, 2024

Goodsell, RCSB Protein Data Bank and Scripps Research. Fast forward to 2023. 1 Yet even after more than two decades of research, media hype, and dozens of clinical trials and biotech start-ups that have come and gone, phage therapy has not scaled. Still, researchers are trying. Read it on our website here.

Therapies 118

Therapies Virus DNA Clinical Trials 118

Elrig

APRIL 29, 2024

With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. Miguel Gancedo Rodrigo Miguel Gancedo Rodrigo Research Investigator, Isomorphic Labs My name is Miguel, and I’m from Murcia, Spain.

Bioinformatics 59

Bioinformatics Molecular Biology Drugs Cell Based Assays 59

Codon

JULY 11, 2023

That’s because proteins are made, in the laboratory, using synthetic DNA and cells; and DNA is expensive. Our machine would make proteins without using any DNA or cells. All cells make proteins in two steps: DNA is transcribed into messenger RNA, which is then translated into protein.

RNA 64

RNA DNA Engineering Laboratories 64

Codon

JULY 11, 2023

That’s because proteins are made, in the laboratory, using synthetic DNA and cells; and DNA is expensive. Our machine would make proteins without using any DNA or cells. All cells make proteins in two steps: DNA is transcribed into messenger RNA, which is then translated into protein.

RNA 52

RNA DNA Engineering Laboratories 52

Codon

MARCH 12, 2023

Notes on Progress is a monthly roundup of papers and ideas about biology and the future. “The recombinant DNA breakthrough has provided us with a new and powerful approach to the questions that have intrigued and plagued man for centuries. Biology is a Burrito. A new base editor to edit mitochondrial DNA.

DNA 52

DNA Engineering RNA Therapies 52

Codon

AUGUST 10, 2023

Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). Journal of Molecular Biology (1961). Nucleic Acids Research (2010).

DNA 91

DNA Cell Biology Molecular Biology Engineering 91

Codon

AUGUST 10, 2023

Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Last edit: 13 September 2023 Progress in biology is arguably moving faster today than at any point in the course of human history. Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. & Ellis T.

DNA 52

DNA Cell Biology Engineering Molecular Biology 52