Drug Discovery World

APRIL 15, 2023

The American Association for Cancer Research (AACR) Annual Meeting is taking place at the Orange County Convention Center in Orlando, Florida from April 14-19, 2023. Tuesday, April 18, 2023, 9am ET Patient-derived TAC01-HER2 TAC T cells produced in Cocoon Platform are highly functional in models of solid tumors – Ling Wang, et al.

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Broad Institute

JUNE 28, 2023

By Broad Communications June 28, 2023 Video Inaugural Merkin Prize in Biomedical Technology awarded to Dr. Marvin Caruthers Dr. Marvin H. Merkin Prize in Biomedical Technology for developing an efficient, automated technology for synthesizing DNA. Caruthers of the University of Colorado, Boulder, has won the inaugural Richard N.

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Drug Discovery World

JUNE 5, 2023

The LSX World Congress 2023 took place at the Business Design Centre in London, UK in May 2023. What do employees expect from their leadership in terms of culture in 2023 and how can we adapt? That is what the business is doing now.” The post Comment: LSX World Congress 2023 appeared first on Drug Discovery World (DDW).

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Broad Institute

OCTOBER 23, 2023

By Makenzie Kohler October 23, 2023 People of South Asian ancestry around the world have more than double the risk of developing cardiometabolic diseases like diabetes, heart attack, and stroke compared to other populations. Some participants will receive a kit in the mail that they can use to send a saliva sample for DNA analysis.

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Drug Discovery World

MARCH 20, 2023

Scientists from Korea have developed a new biosensor that uses fluorescence resonance energy transfer (FRET) to detect DNA double-strand breaks in living specimens in real time. This biosensor has the potential to aid the development of new treatments for DNA damage-related diseases by revealing how our bodies repair damaged DNA.

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Broad Institute

OCTOBER 4, 2023

Marvin Caruthers for developing technology that efficiently synthesizes DNA The inaugural Richard N. Caruthers of the University of Colorado Boulder in a ceremony and symposium at the Broad Institute on September 21, 2023. Merkin Prize in Biomedical Technology was awarded to Marvin H.

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Drug Target Review

NOVEMBER 3, 2023

Organoid group (Hubrecht Institute) researchers, collaborating with researchers at the Princess Máxima Center and Maastricht University, used gut organoids to perform a systematic CRISPR screening of 1800 human transcription factors. 2018 February 8 [2023 November 1];172(4):650-65. The study was published in Science.

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Drugs.com

NOVEMBER 9, 2023

8, 2023 -- Everyone knows smoking to be a major cause of cancer. Now, exactly how tobacco smoke triggers tumor development just got a bit clearer, thanks to new Canadian research. WEDNESDAY, Nov. According to a team at the Ontario Institute for.

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Drug Discovery World

FEBRUARY 2, 2024

The company is building a pipeline of small molecule drugs targeting novel proteins across the DNA mismatch repair (MMR) pathway to generate next-generation immuno-oncology therapeutics to improve clinical outcomes for cancer patients. At AACR-NCI-EORTC in Boston in October 2023, the first disclosure of lead compound NP1867 was presented.

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Drug Discovery World

JUNE 10, 2024

Opening this state-of-the-art facility marks a pivotal moment in the field, as Molecular Devices, one of our key licensees, can now grow organoids at scale to meet the growing demands of researchers worldwide. “It In 2023, the Welsh Government unveiled a Manufacturing Plan for Wales to continue growing the country’s thriving industry.

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Broad Institute

AUGUST 25, 2023

TEST: The Stanley Center for Psychiatric Research - History By Maria Nemchuk August 25, 2023 Breadcrumb Home TEST: The Stanley Center for Psychiatric Research - History The Stanley Center was launched in 2007 with transformative support from the philanthropists Ted and Vada Stanley, through the Stanley Medical Research Institute.

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SCIENMAG: Medicine & Health

AUGUST 28, 2023

WACO, Texas (August 28 , 2023) – Scientific research requires patience. The rewards are not always immediate, and the technology needed does not always exist. Trakselis, Ph.D., professor and director of graduate affairs for the Department of Chemistry and Biochemistry at Baylor University, understands this.

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Broad Institute

AUGUST 31, 2023

Evolved prime editors are smaller and more efficient for therapeutic applications By Corie Lok August 31, 2023 Breadcrumb Home Evolved prime editors are smaller and more efficient for therapeutic applications Researchers have evolved the editing machine at the heart of the prime editing system, which can make a wide range of changes to the genome.

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Elrig

FEBRUARY 23, 2023

Synthetic biology, the answer to ageing, and more at Research & Innovation 2023 Synthetic biology, the answer to ageing, and more at Research & Innovation 2023 The life sciences and drug discovery landscape continues to advance at pace, delivering innovations with the potential to transform patients’ lives across the world.

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Drug Discovery World

OCTOBER 6, 2023

The top stories: mRNA pioneers Katalin Karikó and Drew Weissman receive Nobel prize The Nobel Assembly at Karolinska Institutet has awarded the 2023 Nobel Prize in Physiology or Medicine jointly to Katalin Karikó and Drew Weissman for their discoveries that enabled the development of mRNA vaccines against Covid-19.

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Drug Discovery World

FEBRUARY 8, 2024

In 2023, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. AAV is optimal for gene therapy due to its efficiency and safety in humans; however, AAV processes can present obstacles for researchers. Why are those important?

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Drug Discovery World

APRIL 8, 2024

The American Association of Cancer Research (AACR) Annual Meeting launched on Sunday 7 April in San Diego with an Opening Plenary Session showcasing cutting-edge technological advances opening new frontiers in cancer science.

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Drug Discovery World

APRIL 3, 2023

Galapagos and NovAliX have entered a strategic collaboration in which Galapagos’ research and discovery capabilities and exclusively related employees based in Romainville, France, will be transferred to NovAliX, a drug discovery-focused Contract Research Organisation.

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Broad Institute

JUNE 26, 2023

By Corie Lok June 26, 2023 Credit: Allison Colorado, Broad Communications Chanell Mangum is a research associate in the Broad's Optical Profiling Platform. I have been able to explain my research to senior scientists and also to middle school students since I started working at the Broad.

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Drug Discovery World

JUNE 14, 2023

BRCA1 and BRCA2 are human genes that produce proteins responsible for repairing damaged DNA and play an important role maintaining the genetic stability of cells. Available at: [link] Last accessed: June 2023. Available at: [link] Last accessed: June 2023. Cancer Research UK. Available at: [link] Last accessed: June 2023.

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The Pharma Data

APRIL 11, 2023

Bayer is progressing novel research around its prostate cancer treatment darolutamide. Both small molecule inhibitors in Immuno-Oncology are being jointly developed in a strategic research alliance with the German Cancer Research Center (DKFZ) in Heidelberg, Germany.

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Drug Discovery World

NOVEMBER 30, 2023

Using a technique they’ve dubbed “cancer shredding,” the researchers at Gladstone Institutes programmed CRISPR to zero-in on repeating DNA sequences present only in recurrent tumour cells – and then obliterate those cells by snipping away at them.

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Broad Institute

NOVEMBER 13, 2023

to advance technologies that could transform cancer care By Leah Eisenstadt November 14, 2023 Breadcrumb Home Gerstner Center for Cancer Diagnostics receives additional commitment from Louis V. The researchers are also developing, together with the labs of Sangeeta Bhatia and J. Gerstner, Jr., Gerstner, Jr.,

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Drug Discovery World

NOVEMBER 8, 2023

While traditional approaches to clinical trials have helped us manage some of these conditions to a certain extent, they alone may not provide us the velocity we need to accelerate the research and conquer these diseases, raising the possibility that technologies such as artificial intelligence (AI) may hold the answer.

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Fierce BioTech

OCTOBER 26, 2023

The company has developed a disruptive DNA synthesis platform that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip. The company has developed a disruptive DNA synthesis platform that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip.

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Drugs.com

OCTOBER 4, 2023

4, 2023 -- Going vegetarian is trendy and popular, along with being a healthy choice, but a large portion of those who say they want to stick with a plant-based diet don't. It might come down to your DNA, suggests new research that. WEDNESDAY, Oct.

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Drug Discovery World

FEBRUARY 6, 2024

Technologies like artificial intelligence (AI), machine learning (ML) and robotics/automation are enabling researchers to process enormous data sets and conduct preclinical investigations in record time, speeding up the process and offering greater accuracy. Universities are also using these digital technologies to advance their research.

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PLOS: DNA Science

MARCH 28, 2024

Research also took place in two facilities in Italy, with sponsorship from Italfarmaco S.p.A. million DNA bases. The exons are nestled amongst the much longer introns, which are DNA sequences that are not represented in the final protein. Researchers have been working on developing gene therapy for DMD for decades.

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Drug Discovery World

SEPTEMBER 7, 2022

The Institute of Cancer Research (ICR) has called the decision ‘disappointing’ and ‘frustrating’. Olaparib, which was initially developed to treat women with ovarian and breast cancer, is part of a family of drugs called PARP inhibitors that target and kill cancer cells with faulty DNA repair machinery.

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Drug Discovery World

SEPTEMBER 7, 2023

5 The Research to Accelerate Cures and Equity (RACE) for Children Act of 2017 authorised the Food and Drug Administration (FDA) to require paediatric clinical trials for new oncology drugs with relevant molecular targets and has a had a positive impact on the number of drugs approved in paediatric indications. Read more: $1.5

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Drug Discovery World

FEBRUARY 13, 2023

Yet, the overarching outlook for SLAS2023, taking place from February 25 – March 1, 2023 in San Diego, USA, appears to be a very optimistic one, with the Innovation Accelerated theme showcasing the sector’s get-up-and-go attitude. How can technology help drug discovery research get to market faster and at optimum efficiency?

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Drug Discovery World

MARCH 7, 2023

In 2023, the company revealed data from a Phase III trial which showed that its vaccine candidate DCVax-L more than doubled overall survival in glioblastoma patients. Dr Janette Thomas, CEO, Five Alarm Bio Five Alarm Bio is an anti-ageing therapeutics company, which completed a seed investment round in early 2023.

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Drug Discovery World

OCTOBER 25, 2022

A new laboratory specialising in genomics is set to open at the North Carolina Research Campus (NCRC) in Kannapolis, North Carolina. The Lab will offer the only undergraduate next-generation DNA sequencing (NGS) training in the United States.

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Drug Target Review

NOVEMBER 13, 2023

The instructions to form a cell are encoded in DNA strands, wrapped in proteins and RNA, and wound together into a 3D structure called chromatin. Researchers have long understood that Foxp3 is essential for regulatory T cell development, but only as an on-off switch for regulatory T cell genes.

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Drug Discovery World

MARCH 7, 2023

Both CureLab Oncology and CureLab Veterinary are developing therapies that employ plasmids (circular DNA encoding a gene called p62/SQSTM1). The two sister companies have developed an anti-cancer and anti-inflammatory drug that was contract-manufactured by Aldevron at the time Dr Ballantyne served there as chief scientific officer.

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Broad Institute

JUNE 28, 2023

How chromosome imbalances can drive cancer By Corie Lok June 28, 2023 Breadcrumb Home How chromosome imbalances can drive cancer An analysis of nearly 11,000 human cancers revealed how large chromosomal changes, called aneuploidies, can promote or slow the growth of tumors. Such large-scale changes in DNA have been difficult to study.

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Fierce BioTech

MAY 19, 2023

Download this executive summary to learn how a novel platform can provide clinicians and researchers with access to medical and genetic data that can support innovation in precision medicine. DNAnexus genetics Research Clinical Data Resource Type Whitepaper DNA nexus logo (1).png Download here!

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