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Drug discovery hotspots: India’s Genome Valley

Drug Discovery World

Although pharmaceutical companies had previously been risk-averse and investment in R&D was lower than other countries, leading organisations are looking to increase research spending to 10-12% over the next few years, with biologics and novel chemical entities dominating 4.

Vaccine 130
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Could NfL accelerate drug development for neurodegenerative diseases?

Drug Discovery World

It has been used experimentally in international trials 1 , but researchers are hopeful that further use and evaluation in the UK will accelerate drug development for hard-to-treat neurodegenerative diseases. Biomarkers of Neurodegenerative Diseases: Biology, Taxonomy, Clinical Relevance, and Current Research Status. Biomedicines.

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Women in Stem with Dr Rachel Lagiakos

Drug Target Review

Coupling my desire to be a scientist with my keen sense of adventure, I moved to Alaska out of high school to begin my undergraduate studies in chemistry, applying myself to my STEM classes whilst also climbing mountains and chasing Northern Lights.

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Welcome to new Director David Hulcoop

The Open Targets Blog

David Hulcoop, previously Strategy and Operations Director for the consortium, starts as Executive Director of Open Targets in October 2023. After completing my PhD in organic chemistry at the University of Cambridge, I went to Canada as a Leverhulme Trust postdoctoral fellow. I’m a chemist by training.

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What to expect from PEGS Europe 2023: Day 1

Drug Discovery World

On Day 1, Tuesday 14 November 2023, the tracks include: Display of biologics, antibody-based cancer therapies, safety and efficacy of bispecific antibodies, modulating the tumour microenvironment, optimisation and developability, and cell line and systems engineering. from engineered peptide and antibody libraries’.

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Antibody Drug Conjugates: windows of opportunity

Drug Target Review

Patient advocacy groups, such as Friends of Cancer Research, are also encouraging regulators to ensure drug developers in the oncology space invest in the optimisation of dosing regimens to help better balance efficacy and safety and thereby deliver more effective patient outcomes. 2022 Nov 14 [cited 2023 Apr 6];40(11):1255–63.

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What to expect from PEGS Europe 2023: Day 3

Drug Discovery World

On Day 3, Thursday 16 November 2023, the tracks include: the second part of machine learning for protein engineering, antibodies against membrane protein targets, engineering bispecific antibodies, next-generation immunotherapies, protein stability and formulation, and protein process development.