Drug Discovery World

JANUARY 21, 2024

Most drugs under development today are designed to do the same thing: inhibit the function of proteins that contribute to disease. But this strategy misses a vast therapeutic opportunity: addressing the many diseases that are caused by insufficient levels or impaired function of otherwise beneficial proteins,” Bushell explains. “By

Vaccine 130

Vaccine Computational Chemistry Animal Testing Engineering 130

Broad Institute

JUNE 27, 2024

By Greta Friar, Whitehead Institute June 27, 2024 Images of a mouse brain show the effect of a technology called CHARM in turning off the expression of a gene in the brain. CHARMs are an elegant solution to the problem of silencing disease genes, and they have the potential to have an important position in the future of genetic medicines.”

Disease 142

Disease Therapies Engineering Clinical Trials 142

PLOS: DNA Science

APRIL 4, 2024

A Compelling Need I was delighted to discover that the inspiration for Lume is a rare, recessive genetic disease, trimethylaminuria (TMAU), aka “fish odor syndrome.” ” But, tellingly, “Neither the law nor FDA regulations require specific tests to demonstrate the safety of individual products or ingredients.”

Disease 88

Disease Testimonials Production FDA 88

Codon

JULY 21, 2024

These rats, known as AA or P-lines, serve as animal models of alcoholism, exhibiting high alcohol-seeking behavior, withdrawal symptoms, and a predisposition to co-abuse ethanol and nicotine. Of course, AA and P-line rats are not the only research animals bred for the study of disease. 1 Subscribe to Asimov Press.

Research 113

Research Engineering Science Disease 113