2024 Disease DNA Protein Expression 
Drug Discovery World
SEPTEMBER 25, 2024
Mylotarg was ahead of its time in many ways: its novel structure of an antibody to target diseased cells, plus a cancer-killing payload attached via a special linker, is the blueprint for the antibody-drug conjugates (ADCs) that followed. Challenges for ADCs There are, of course, challenges for ADCs.
Broad Institute
OCTOBER 4, 2023
Related links Merkin Prize Inaugural Merkin Prize in Biomedical Technology awarded to Dr. Marvin Caruthers for developing technology that efficiently synthesizes DNA The inaugural Richard N. Nominations for the 2024 Merkin Prize opened on September 6, 2023 and close on December 6, 2023 at 11:59 pm ET.
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Drug Discovery World
APRIL 17, 2024
Recently, research published by Dr Richard (Rick) Young (Whitehead Institute) describes the key mechanism of how these regRNAs regulate gene expression. CAMP4 is exploiting these regulatory interactions to specifically control the expression of genes tied to disease. What diseases are you currently targeting?
Drug Target Review
JANUARY 26, 2024
To find a DNA fragment that contained the intact ACE2 gene, complete with its embedded regulatory information, they searched libraries of cloned DNA fragments generated as part of the Human Genome Project. 2020 March 30 [2024 January 22]; 581:215-220. This study was published in Virology. Reference 1 Fan S, Ge J, Lan J, et al.
Broad Institute
JUNE 27, 2024
By Greta Friar, Whitehead Institute June 27, 2024 Images of a mouse brain show the effect of a technology called CHARM in turning off the expression of a gene in the brain. Credit: Neumann EN, Bertozzi TM, et al. Credit: Neumann EN, Bertozzi TM, et al.
Drug Discovery World
APRIL 30, 2024
Whilst research into mRNA has been ongoing for decade, interest has sparked in recent years and research has begun to expand into areas of vaccinology, infectious diseases and other indications. Its job is to carry coding information that is essential to the translation and processing of functional proteins.
Alta Sciences
APRIL 17, 2024
Five Promising Treatment Areas in Early-Phase Drug Development in 2024 aasimakopoulos Wed, 04/17/2024 - 15:52 Early-phase drug development is an ever-changing landscape, as emerging science leads to new promising areas of research for the treatment of human health issues.
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