Remove 2024 Remove Disease Remove Drug Development Remove Molecular Biology
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Medicinal Chemistry In The Age Of Artificial Intelligence

LifeSciVC

We are constantly reminded how we are in the midst of an artificial intelligence revolution of the drug development process which promises to completely transform how we develop drugs with increases in productivity of an order of magnitude or more.

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How 3D genomics can accelerate personalised medicine

Drug Discovery World

Importantly, only a small fraction of the human genome codes for proteins; the majority (~ 98%) consists of non-coding DNA, which plays a critical role in gene regulation, cellular identity, and disease susceptibility. Therefore, it is highly likely that deciphering the mechanism of action of enhancers is key to understanding human disease.

DNA 130
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Europe: Where is the drug discovery innovation?

Drug Discovery World

Even before this, however, Amsterdam was established as an important centre for drug development. The company is now investigating a promising gene therapy for Huntingdon’s disease in a Phase I/II trial, with patients already showing signs of preserved neurological function. The CDD will sponsor and manage KWF-supported trials.

Drugs 147
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Key industry partnerships advancing drug discovery

Drug Discovery World

Makoto Inoue, President and Representative Director of Otsuka Pharmaceutical commented: “Otsuka is committed to the development of drugs for rare diseases such as autosomal dominant polycystic kidney disease (ADPKD). His research focuses on immunotherapies for patients with breast cancer.

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Tackling pain and mental health with plant-based medicines

Drug Discovery World

RA: What advantages does a plant-based approach bring to drug development? These confounding factors limit the opportunity for big pharma, especially considering the poor access to the complex small molecule pharmacophores known to have a link to the target disease and from which drug discovery programmes can be rolled out.

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What is the largest CRO in the US?

Vial

Leading Global CROs To advance new therapies, pharma, biotech, and medical device sponsors engage CROs to help navigate the complex landscape of drug development and regulatory pathways and to manage clinical trials efficiently, ethically, and in compliance with good clinical practice ( GCP ) standards. from 2024 to reach US$129.8

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The future outlook for mRNA therapies

Drug Discovery World

Messenger RNA (mRNA) has come into focus within the drug discovery and development as an exciting tool to deliver genetic information. Whilst research into mRNA has been ongoing for decade, interest has sparked in recent years and research has begun to expand into areas of vaccinology, infectious diseases and other indications.

Therapies 130