Drug Discovery World

APRIL 17, 2024

CAMP4 is exploiting these regulatory interactions to specifically control the expression of genes tied to disease. Our proprietary RAP Platform identifies the most impactful regRNA for a given gene and programmes anti-sense oligonucleotides (ASOs) to engage the regRNA and amplify mRNA production. Can you give some examples?

Science 147

Science RNA Disease Protein Expression 147

Drug Discovery World

APRIL 30, 2024

Whilst research into mRNA has been ongoing for decade, interest has sparked in recent years and research has begun to expand into areas of vaccinology, infectious diseases and other indications. Its job is to carry coding information that is essential to the translation and processing of functional proteins.

Therapies 130

Therapies RNA Vaccine Small Molecule 130

Broad Institute

MARCH 22, 2024

Messenger RNAs with multiple “tails” could lead to more effective therapeutics By Corie Lok March 22, 2024 Breadcrumb Home Messenger RNAs with multiple “tails” could lead to more effective therapeutics Scientists have engineered long lasting mRNAs that increased therapeutic protein production in cells and animals.

Engineering 140

Engineering Protein Production RNA Vaccine 140

Agency IQ

APRIL 12, 2024

Draft guidance on potency assays for CGT products garners extensive stakeholder input Late last year, the FDA published a draft update to its 2011 guidance on potency assays for cell and gene therapy products, unveiling a major shift in approach to the issue. for gene therapies that use viral or nonviral vectors).

Production 40

Production FDA Therapies Biochemical Assays 40

Drug Discovery World

NOVEMBER 9, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Alice Rothnie, DPhil, Senior Lecturer, Biochemistry, Aston University, on: ‘Membrane protein production using insect cells’.

Engineering 130

Engineering Protein Production Therapies Science 130

Drug Discovery World

NOVEMBER 8, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Claudia Rinnofner, PhD, Founder & CEO, myBIOS GmbH, on: “Novel strategies for protein production using Pichia pastoris”.

Engineering 162

Engineering Protein Expression Therapies Science 162

Drug Discovery World

NOVEMBER 13, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. These topics include: High-throughput (HTP) protein production and AI and automation in bioprocess development.

Engineering 147

Engineering Science Bioinformatics Vaccine 147