Drug Discovery World

FEBRUARY 8, 2024

In 2023, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. Questions were fielded from the audience, which included: What analysis will be performed to evaluate host or other DNA contamination? Why are those important?

Therapies 147

Therapies Bioinformatics Packaging Molecular Biology 147

Alta Sciences

MARCH 1, 2024

Q&A With Dr. Norbert Makori and Pierre Jolicoeur: The Benefits of Combining Preclinical and Bioanalytical for Your Gene Therapy Studies pmjackson Fri, 03/01/2024 - 22:20 Recent advances in gene therapy have allowed for diseases to be approached differently. Q&A With Dr. We have a supply of NHPs to ensure prompt study start.

Therapies 52

Therapies Laboratories Molecular Biology RNA 52

Broad Institute

MAY 14, 2024

William Studier for development of widely used protein- and RNA-production platform By Corie Lok May 14, 2024 Breadcrumb Home Merkin Prize in Biomedical Technology awarded to F. By Broad Communications May 14, 2024 F. Studier will be honored in a prize ceremony held on September 17, 2024. Photo courtesy of BNL.

RNA 84

RNA Production Molecular Biology Laboratories 84

Drug Discovery World

APRIL 30, 2024

This novel approach allows for the modulation of mRNA biology to either increase or decrease protein production, offering the versatility to target a wide range of mechanisms of action (MOA),” Slonim states. At the start of 2024, the first patients in a clinical trial investigating an mRNA cancer therapy were dosed.

Therapies 130

Therapies RNA Vaccine Small Molecule 130

Codon

FEBRUARY 13, 2024

doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.

Therapies 118

Therapies Virus DNA Clinical Trials 118

Codon

JUNE 25, 2024

However, they plod along as they clone plasmids—the loops of DNA that biologists use to manipulate and study organisms—because propagating them relies, in part, on the pace at which cells grow and divide. Most medicines, including insulin and semaglutide (the weight loss drug), are made using DNA cloning. However, E.

DNA 70

DNA RNA Laboratories Engineering 70

Drug Discovery World

NOVEMBER 9, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Klaus Wagenbauer, PhD, Founder & CEO, Plectonic, on: ‘Programmable DNA-origami-based T cell engagers: PTE’.

Engineering 130

Engineering Therapies Protein Production Science 130