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Guide to using AAV vectors in gene therapy

Drug Discovery World

In 2023, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. For the AAV packaging service, what is the titer of the viral particles? Dr O’Hara also provided an AAV plasmid preparation case study. Why are those important?

Therapies 147
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Analysis Life Sciences Thank You Revised ICH viral safety guideline: NGS is in, animal use (mostly) out

Agency IQ

BY RACHEL COE, MSC | JAN 17, 2024 12:16 AM CST Quick background on cell line development Despite technological advancements in synthetic biology, all biological products today make use of harvested cellular material (or “substrate”) in one way or another. First, viral contaminants may be introduced from starting materials.

Virus 40
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Scaling Phage Therapy

Codon

doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.

Therapies 118