Codon

FEBRUARY 13, 2024

Regulators traditionally want to see a single, stable, well-characterized drug before giving the green light for it to be tested in a clinical trial, not dozens of different viruses; let alone ones that are best found in unappealing places like sewage , hospital waste, or bird poop.

Therapies 124

Therapies Virus DNA Clinical Trials 124

Alta Sciences

AUGUST 21, 2024

Internships at Altasciences: Q&A With Our Summer Interns nbartlett Thu, 08/22/2024 - 04:44 Internships at Altasciences are more than just a stepping stone—they’re a gateway to real-world-experience and professional growth, giving the next generation opportunities to help shape progress in the drug development industry.

International 40

International Laboratories Science Molecular Biology 40

Codon

APRIL 2, 2024

I was reading a lot of molecular biology papers about different systems, especially circadian clocks, and also a book called Biological Feedback , by Thomas and D’Ari, that sketched out really simple models for different kinds of feedback circuits. So many kinds of people have contributed to biology in different ways.

RNA 56

RNA Engineering Molecular Biology Synthetic Chemistry 56

Codon

JUNE 25, 2024

Sometimes cells don’t take up the DNA, or unforeseen issues with the modified sequence arise—such as off-target mutations, unexpected protein modifications, or disruptions to gene regulation—that send us back to the drawing board. ” Asimov Press (2024). These setbacks can extend the timeline from days to weeks.

DNA 75

DNA RNA Laboratories Research 75

Codon

JUNE 18, 2024

Even after a half-century of molecular biology research, scientists didn’t know until recently how gas vesicles physically trap gas while occluding water. For more than a century, scientists thought of gas vesicles as little more than a natural curiosity and, later, as a way for microbes to regulate buoyancy.

Engineering 67

Engineering Laboratories International Clinical Trials 67

Agency IQ

JANUARY 19, 2024

BY RACHEL COE, MSC | JAN 17, 2024 12:16 AM CST Quick background on cell line development Despite technological advancements in synthetic biology, all biological products today make use of harvested cellular material (or “substrate”) in one way or another. This bulk product contains both the final product (e.g.,

Virus 40

Virus Science Production FDA 40

Broad Institute

NOVEMBER 20, 2024

Scientists find a region of the mouse gut tightly regulated by the immune system By Allessandra DiCorato November 20, 2024 Breadcrumb Home Scientists find a region of the mouse gut tightly regulated by the immune system A spatial map of gene expression across the intestine reveals the organ’s remarkable adaptability.

Regulations 84

Regulations Immune Response Molecular Biology Disease 84

Drug Target Review

FEBRUARY 19, 2025

These challenges were the focus of a panel discussion at the 2024 Advanced Therapies Europe (ATE24) conference, led by two prominent experts: Dr Boris Greber, Head of R&D, iPSC at Catalent Cell & Gene Therapy in Europe, and Dr Frederic Cedrone, Vice President of Corporate Innovation at Catalent.

Therapies 59

Therapies Molecular Biology Regulations Packaging 59

Drug Target Review

DECEMBER 12, 2024

Any study of the genome is incomplete without considering the epigenomic framework within which genes are read and regulated. 2024 Sep 26 [cited 2024 Sep 27]; Available from: [link] Sheng CC, Hao J, Hong CC. Progress in molecular biology and translational science [Internet]. 2024 Jan 1 [cited 2024 Oct 22];185209.

Therapies 59

Therapies DNA Molecular Biology Immune Response 59

Codon

JANUARY 8, 2025

million in 2024, according to Cognitive Market Research. The same report suggested that in 2024, North America held a major market share, accounting for more than 40 percent of the global revenue, with a market size of $7,417.00 In ideal circumstances, our circadian rhythms work well and regulate our hormonal cycles and mood.

Science 60

Science Vaccine Engineering Disease 60

BMG Labtech

FEBRUARY 24, 2025

Protein nitration is one example that takes place on tyrosine residues which can have important consequences for the regulation of biological processes. Protein nitration assays are widely used in many research areas including but not limited to biochemistry , biotechnology , cell biology , microbiology , and molecular biology.

Small Molecule 52

Small Molecule Disease Licensing Licensing 52

Codon

DECEMBER 1, 2024

By Matthew Cobb The Central Dogma is a linchpin for understanding how cells work, and yet it is one of the most widely misunderstood concepts in molecular biology. That is pretty much exactly what happens in many microbes; gene regulation responds to environmental stimuli. ” Asimov Press (2024). Cite: Cobb, Matthew.

RNA 124

RNA DNA Molecular Biology Virus 124

Codon

NOVEMBER 1, 2024

I’ve chosen these two because I think they are the linchpin by which we’ll be able to build broadly useful AI models for cell and molecular biology. But looking ahead to the second bottleneck, what does it mean to say that biology is “complex”? Nature (2024). Credit: Dorkenwald S.

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DNA RNA Molecular Biology Laboratories 114