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2024 predictions: Experts comment on monoclonal antibodies 

Drug Discovery World

DDW’s Megan Thomas speaks to experts from the drug discovery industry about their predictions on what 2024 holds for our sector. Amanda Halford, President Bioprocess, Cytiva “In 2024, the emphasis will remain on novel mAbs, specifically antibody drug conjugates. This is part of a series of predictions based on different themes.

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Therapeutic antibody potential in 2024

Drug Discovery World

DDW’s Megan Thomas speaks to industry experts and thought leaders about the potential for therapeutic antibodies in 2024. Artificial intelligence (AI) AI is on everyone’s minds as we head into 2024; of course, this is across not just the drug discovery spectrum but is particularly relevant to therapeutic antibodies.

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Tackling pain and mental health with plant-based medicines

Drug Discovery World

These confounding factors limit the opportunity for big pharma, especially considering the poor access to the complex small molecule pharmacophores known to have a link to the target disease and from which drug discovery programmes can be rolled out. RA: Could you discuss the concept of new-to-nature?

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Key industry partnerships advancing drug discovery

Drug Discovery World

We are excited to enter into this partnership with Shionogi, a company sharing the same patient centric values as Sobi and look forward to launching cefiderocol from 2024.” Dr Isaac Chan, an Assistant Professor in UT Southwestern’s Departments of Internal Medicine and Molecular Biology, will be the primary advisor for the collaboration.

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The future outlook for mRNA therapies

Drug Discovery World

It’s worth noting that the approach of small molecules interacting with mRNA biology represents a relatively new and potentially broader and more effective strategy. At the start of 2024, the first patients in a clinical trial investigating an mRNA cancer therapy were dosed. Sig Transduct Target Ther 2022;7:166.

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AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

Fascinated by the potential of AI in medical research, I transitioned to BenevolentAI in early 2023 as a Biology Project Leader. There, I supported AI-enabled DD efforts in their small molecule portfolio. Joining Isomorphic Labs in October 2024, I’m thrilled to be part of their mission to revolutionize DD through AI/ML.

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The role of anti-viral drug development in a new pandemic era

Drug Target Review

Advances in molecular biology have led to highly safe, efficient, and effective platforms, such as mRNA, that can be rapidly re-purposed for different pathogens, multiple pathogens, or new strains of evolving pathogens. 2023 [cited 2024 Jan 22]. 2023 [cited 2024 Jan 22]. 2019 [cited 2024 Jan 22]. 29, 2023] | U.S.