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Streamlining Therapeutic Antibody Production with Innovative Workflow Solutions – Optimizing the Scale Up of Transient Expression

Fierce BioTech

Comparable Results: Achieve cell growth and protein expression levels similar to those obtained with smaller-scale shake flasks. On Demand Start Date Tue, 10/29/2024 - 09:00 Don’t miss this opportunity to enhance your scale-up processes with new solutions. Register now to secure your spot!

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A therapy candidate for fatal prion diseases turns off disease-causing gene

Broad Institute

By Greta Friar, Whitehead Institute June 27, 2024 Images of a mouse brain show the effect of a technology called CHARM in turning off the expression of a gene in the brain. Brain-wide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editor. Online June 27, 2024.

Disease 142
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Five Promising Treatment Areas in Early-Phase Drug Development in 2024

Alta Sciences

Five Promising Treatment Areas in Early-Phase Drug Development in 2024 aasimakopoulos Wed, 04/17/2024 - 15:52 Early-phase drug development is an ever-changing landscape, as emerging science leads to new promising areas of research for the treatment of human health issues.

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SARS-CoV-2: advancing the production of the ACE2 protein

Drug Target Review

To test whether the mouse-made human ACE2 proteins were functional, the researchers used numerous methods, which included demonstrating that a psuedovirus containing the Covid spike protein could bind to the receptors and infect cells. 2020 March 30 [2024 January 22]; 581:215-220. This study was published in Virology.

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ELRIG UK and The Protein Society Partner to Advance Protein Sciences in Drug Discovery

Elrig

Working together will enable the organisations to create a productive interdisciplinary forum that incorporates diverse research interests and experimental approaches, offering their drug discovery and protein science communities the opportunity to connect and share ideas.

Science 52
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Marina Saffold

Broad Institute

We hypothesized that these small molecules would similarly decrease the expression of chromatin proteins in hiPSC-derived astrocytes.

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Q&A: Single-cell and spatial proteomics reveal proteins’ nuanced roles in health and disease

Broad Institute

By Ari Navetta September 5, 2024 Credit: Allison Colorado, Broad Communications Claudia Ctortecka, a postdoctoral associate in the Proteomics Platform, works with proteomics samples in the lab.

Disease 85