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Improving quality control for CAR T cell therapies

Drug Discovery World

CAR T cells are made by transfecting T cells with a transgene that encodes the CAR protein using either a virus, a transposon system, or mRNA. MOI is the ratio between virus concentration and cell concentration, and with ddPCR assays, the researchers found that as MOI increased, so did copy number.

Therapies 246
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Pfizer Investor Day Features Significant Number of Pipeline Advances for COVID-19 Programs and Across Numerous Therapeutic Areas

The Pharma Data

27 key programs highlighted, including assets that could potentially contribute revenue by 2025 and others in the 2026-2028 time frame. An update on Pfizer’s potential first-in-class maternal vaccine candidate for the prevention of respiratory syncytial virus (RSVpreF). BNT162 mRNA-based Vaccine Program. for RSV A and 18.0

Vaccine 52